Top

International Urogynecology Journal

Published in:

Open Access 01-08-2009 | Original Article

The association between diabetes mellitus and urinary incontinence in adult women

Authors: Yenal Izci, Pınar Topsever, T. Müge Filiz, Nursan Dede Çınar, Cefariye Uludağ, Toine Lagro-Janssen

Published in: International Urogynecology Journal | Issue 8/2009

Abstract

Introduction and hypothesis

The purpose of the study was to investigate the relationship of diabetes mellitus and urinary incontinence in adult women.

Methods

We conducted a cross-sectional, comparative study with a case-control design. One thousand three hundred eighty-one women (aged 20–87 years) attending six Primary Healthcare Centers in Turkey were enrolled in this study, after giving their informed consent. Subjects were dichotomized into cases and controls according to presence of diabetes mellitus (DM) and were matched for the confounding factors age, body mass index (BMI), and reproductive history.

Results

Nine hundred ten women were included: 273 diabetics and 637 non-diabetics. Diabetes was shown to be associated with a 2.5-fold risk increase for urinary incontinence (UI), and age and BMI were weakly associated with UI. UI was significantly more prevalent in diabetic women: 41% diabetic and 22.1% non-diabetic women reported UI (p < 0.001). Age, BMI, and DM were revealed as independent determinants of UI in adult women. Urge incontinence was more prevalent in non-diabetic women, whereas stress and mixed incontinence were more prevalent among diabetic women.

Conclusions

DM is the most important independent determinant of UI.

Tuomelihto J, Lindström J, Eriksson JG et al (2001) Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance. N Engl J Med 344:1343–1350CrossRef

Teunissen D, van Weel C, Lagro-Janssen T (2005) Urinary incontinence in older people living in the community: examining help-seeking behavior. Br J Gen Pract 55:776–782PubMed

Teunissen D, van den Bosch W, van Weel C, Lagro-Janssen T (2006) “It can always happen”: the impact of urinary incontinence on elderly men and women. Scan J Prim Health Care 24:166–173CrossRef

Hunskaar S, Lose G, Sykes D, Voss S (2004) The prevalence of urinary incontinence in women in four European countries. Br J Urol 93:324–330

Minassian VA, Drutz HP, Al-Badr A (2003) Urinary incontinence as a worldwide problem. Int J Gynaecol Obstet 82:327–338PubMedCrossRef

Ozerdogan N, Beji NK, Yalcin O (2004) Urinary incontinence: its prevalence, risk factors and effects on the quality of life of women living in a region of Turkey. Gynecol Obstet Invest 58:145–50 (Abstract only)PubMedCrossRef

Kocak I, Okyay P, Dundar M, Erol H, Beser E (2005) Female urinary incontinence in the west of Turkey: prevalence, risk factors and impact on quality of life. Eur Urol 48:634–41PubMedCrossRef

Maral I, Ozkardes H, Peskircioglu L, Bumin MA (2001) Prevalence of stress urinary incontinence in both sexes at or after age 15 years: a cross-sectional study. J Urol 165:408–12PubMedCrossRef

Filiz TM, Topsever P, Uludag C, Gorperioglu S, Cinar N (2007) Effects of age and urinary incontinence severity on generic SF-36 quality of life measurements in Sakarya, Turkey. Turk Klin J Med Science 27:189–194

10.

Lifford KL, Curhan GC, Hu FB, Barbiere RL, Grodstein F (2005) Type 2 diabetes mellitus and risk of developing urinary incontinence. J Am Geriatr Soc 53:1851–1857PubMedCrossRef

11.

Brown JS (2005) Urinary incontinence: an important and underrecognized complication of type 2 diabetes mellitus. J Am Geriatr Soc 53:2028–2029PubMedCrossRef

12.

Jackson SL, Scholes D, Boyko EJ, Abraham L, Fihn SD (2005) Urinary incontinence and diabetes in postmenopausal women. Diabetes Care 28(7):1730–1738PubMedCrossRef

13.

Brown JS, Vittinghoff E, Lin F, Nyberg LM, Kusek JW, Kanaya AM (2006) Prevalence and Risk factors of urinary incontinence in women with type 2 diabetes and impaired fasting glucose. Diabetes Care 26(6):1307–1312CrossRef

14.

Smith DB (2006) Urinary incontinence and diabetes (review). J WOCN 33(6):619–623

15.

Ebbesen MH, Hannestad YS, Midthjell K, Hunskaar S (2007) Diabetes and urinary incontinence—prevalence data from Norway. Acta Obstet Gynecol Scan 86:1256–1262CrossRef

16.

Lewis CM, Schrader R, Many A, Mackay M, Rogers RG (2005) Diabetes and urinary incontinence in 50- to 90-year-old women: a cross-sectional population-based study. Am J Obstet Gynecol 193:2154–2158PubMedCrossRef

17.

Brown JS, Wing R, Barrett-Connor E, Nyberg LM, Kusek JW, Orchard TJ et al (2006) Lifestyle intervention is associated with lower prevalence of urinary incontinence—the diabetes prevention program. Diabetes Care 29:385–390PubMedCrossRef

18.

Danforth KN, Townsend MK, Lifford K, Curhan GC, Resnick NM, Grodstein F (2006) Risk factors for urinary incontinence among middle-aged women. Am J Obstet Gynecol 194:339–345PubMedCrossRef

19.

van Gerwen M, Schellevis F, Lagro-Janssen ALM (2007) Comorbidities associated with urinary incontinence: a case-control study from the Second Dutch National Survey of General Practice. JABFM 20:608–610PubMedCrossRef

20.

Kuh D, Cardozo L, Hardy R (1999) Urinary incontinence in middle aged women: childhood enuresis and other lifetime risk factors in a British prospective cohort. J Epidemiol Community Health 53:453–458PubMedCrossRef

21.

Kebapci N, Yenilmez A, Efe B, Entok E, Demirustu C (2007) Bladder dysfunction in type 2 diabetic patients. Neurourol Urodyn 26:814–819PubMedCrossRef

22.

Hill SR, Fayyad AM, Jones GR (2008) Diabetes mellitus and female lower urinary tract symptoms: a review. Neurourol Urodyn 27(5):362–7PubMedCrossRef

23.

Haslam J (2006) Stress urinary incontinence, whose problem is it? J Community Nurs 20:17–20

24.

Subak LL, Whitcomb E, Shen H, Saxton J, Vittinghoff E, Brown JS (2005) Weight loss: a novel and effective treatment for urinary incontinence. J Urol 174:190–195PubMedCrossRef

25.

Filiz TM, Uludag C, Cinar N, Gorperioglu S, Topsever P (2006) Risk factors for urinary incontinence in Turkish women: a cross-sectional study. Saudi Med J 27(11):1688–1692PubMed

26.

Hägglund D, Walker-Engström ML, Larson G, Leppert J (2003) Reasons why women with long-term urinary incontinence do not seek professional help: a cross-sectional population-based cohort study. Int Urogynecol J 14:296–304CrossRef

Title: The association between diabetes mellitus and urinary incontinence in adult women
Authors: Yenal Izci
Pınar Topsever
T. Müge Filiz
Nursan Dede Çınar
Cefariye Uludağ
Toine Lagro-Janssen
Publication date: 01-08-2009
Publisher: Springer-Verlag
Published in: International Urogynecology Journal / Issue 8/2009
Print ISSN: 0937-3462
Electronic ISSN: 1433-3023
DOI: https://doi.org/10.1007/s00192-009-0888-8

Keynote webinar | Spotlight on medication adherence

Springer Medicine

The association between diabetes mellitus and urinary incontinence in adult women

Abstract

Introduction and hypothesis

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Introduction and hypothesis

Methods

Results

Conclusions

Please log in to get access to this content

Other articles of this Issue 8/2009

Caldesmon expression is decreased in women with anterior vaginal wall prolapse: a pilot study

Outcome of obstetric anal sphincter injuries (OASIS)—role of structured management

Vaginal noise: prevalence, bother and risk factors in a general female population aged 45–85 years

Complications of vaginal mesh: our experience

Holmium laser treatment of a vesical calculus secondary to TVT procedure

Novel approach for correction of urethral prolapse using a retropubic sling with urethral fixation