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01-05-2008 | Original Article

Painful bladder syndrome/interstitial cystitis and vulvodynia: a clinical correlation

Authors: Kenneth Peters, Benjamin Girdler, Donna Carrico, Ibrahim Ibrahim, Ananias Diokno

Published in: International Urogynecology Journal | Issue 5/2008

Abstract

Vulvodynia affects 25% of women with painful bladder syndrome/interstitial cystitis (PBS/IC). The objective of our study was to clinically evaluate the association of PBS/IC and vulvodynia and possible contributing factors. To our knowledge, this has not been reported. Seventy women with PBS/IC were evaluated from December 2005 to December 2006 with a comprehensive history and exam. Two groups were formed—those with vulvodynia and those without vulvodynia for comparison. Of the women, 51.4% had vulvodynia and 48.6% did not have vulvodynia using our operative definition. Average levator pain levels were significantly greater in those with vulvodynia. There was no significant difference in the total number of lifetime pelvic surgeries, history of sexually transmitted infections (STIs), vaginitis, or abuse history between groups. The correlation of vulvodynia and PBS/IC may have been underestimated. Research needs to explore the link between precipitating factors, symptoms, and effective treatment options for PBS/IC and vulvodynia.

Hanno PM (2006) Painful bladder syndrome/interstitial cystitis and related disorders. In: Wein AJ, Kavoussi LR, Novick AC, Partin AW, Peters CA (eds) Campbell’s urology. 9th edn. Saunders Elsevier, Philadelphia, pp 1–57 Chapter 10

Haefner HK, Collins ME, Davis GD, Edwards L, Foster DC, Hartmann ED, Kaufman RH, Lynch PJ, Margesson LJ, Moyal-Barracco M, Piper CK, Reed BD, Stewart EG, Wilkinson EJ (2005) The vulvodynia guideline. J Low Genit Tract Dis 9(1):40–51PubMedCrossRef

Pukall CF, Binik YM, Khalife S, Amsel R, Abbott FV (2002) Vestibular tactile and pain thresholds in women with vulvar vestibulitis syndrome. Pain 96:163–175PubMedCrossRef

Reed BD (2006) Vulvodynia: diagnosis and management. Am Fam Phys 73(7):1231–1239

Bergeron S, Binik YM, Khalife S, Pagidas K, Glazer HI (2001) Vulvar vestibulitis syndrome: reliability of diagnosis and evaluation of current diagnostic criteria. Obstet Gynecol 98:45–51PubMedCrossRef

Alagiri M, Chottiner S, Ratner V, Slade D, Hanno PM (1997) Interstitial cystitis: unexplained associations with other chronic disease and pain syndromes. Urology 49(Suppl 5A):52–57PubMedCrossRef

Goetsch MF (1991) Vulvar vestibulitis: Prevalence and historic features in a general gynecologic practice population. Am J Obstet Gynecol 164(6 pt 1):1609–1614PubMed

Reed BD, Crawford S, Couper M, Cave C, Haefner HK (2004) Pain at the vulvar vestibule: a web–based survey. J Low Genit Tract Dis. 8:48–57PubMedCrossRef

Harlow BL, Stewart EG (2003) A population-based assessment of chronic unexplained vulvar pain: have we underestimated the prevalence of vulvodynia? J Am Med Women’s Assoc 58:82–88

10.

Travell JG, Simons DG (1992) Myofascial pain and dysfunction—the trigger point manual vol. 2. Williams & Wilkins, Baltimore, pp 112–126

11.

Mathias SD, Kuppermann M, Liberman RF, Lipschutz RC, Steege JF (1996) Chronic pelvic pain: prevalence, health-related quality of life, and economic correlates. Obstet Gynecol 87(3):321–327PubMedCrossRef

12.

Lowenstein L, Vardi Y, Deutsch M, Friedman M, Gruenwald I, Granot M, Sprecher E, Yarnitsky D (2004) Vulvar vestibulitis severity—assessment by sensory and pain testing modalities. Pain 107:47–53PubMedCrossRef

13.

Edwards L, Mason M, Phillips M, Norton J, Boyle M (1997) Childhood sexual and physical abuse. Incidence in patients with vulvodynia. J Reprod Med 42(3):135–139PubMed

14.

Reed BD, Haefner HK, Punch MR, Roth RS, Gorenflo DW, Gillespie BW (2000) Psychosocial and sexual functioning in women with vulvodynia and chronic pelvic pain: a comparative evaluation. J Reprod Med 45:624–632PubMed

15.

Harlow BL, Stewart EG (2005) Adult-onset vulvodynia in relation to childhood violence victimization. Am J Epidemiol 161:871–880PubMedCrossRef

16.

Office on Women’s Health—US Dept. of Health and Human Services-2005 Statistics. http://healthstatus2010.com accessed 6-26-07

17.

The Commonwealth Fund, Health Concerns Across a Woman’s Lifespan: 1998 Survey of Women’s Health, May 1999

18.

Glazer HI, Rodke G, Swencionis C, Hertz R, Young AW (1995) Treatment of vulvar vestibulitis syndrome with electromyographic biofeedback of pelvic floor musculature. J Reprod Med 40:283–290PubMed

19.

Peters KM, Carrico DJ, Kalinowski SE, Ibrahim IA, Diokno AC (2007) Prevalence of pelvic floor dysfunction in patients with interstitial cystitis. Urology 70:16–18PubMedCrossRef

20.

Leppert P, Turner M. Vulvodynia: toward understanding a pain syndrome. Proceedings from the Workshop April 14–15, 2003, US Dept HHS-NIH; p 1–42

21.

Bornstein J, Goldschmid N, Sabo E (2004) Hyperinnervation and mast cell activation may be used as histopathologic diagnostic criteria for vulvar vestibulitis. Gynecol Obstet Investig 58:171–178CrossRef

22.

Theoharides TC, Kempuraj D, Sant GR (2001) Mast cell involvement in interstitial cystitis: a review of human and experimental evidence. Urology 57(suppl 6A):47–55PubMedCrossRef

23.

Theoharides TC (2004) Panic disorder, interstitial cystitis, and mast cells. J Clin Psychopharmacol 24(4):361–364PubMedCrossRef

24.

Green M, Filippou A, Sant G, Theoharides TC (2004) Expression of intercellular adhesion molecules in the bladder of patients with interstitial cystitis. Urol 63:688–693PubMedCrossRef

25.

Edwards L (2003) New concepts in vulvodynia. Am J Obstet Gynecol 189:S24–S30PubMedCrossRef

26.

Reissing ED, Brown C, Lord MJ, Binik YM, Khalife S (2005) Pelvic floor muscle functioning in women with vulvar vestibulitis syndrome. J Psychosom Obstet Gynaecol 26(2):107–113PubMedCrossRef

27.

Wein A, Hanno P (2002) Targets for therapy of the painful bladder. Urology 59(Suppl 5A):69–72

Title: Painful bladder syndrome/interstitial cystitis and vulvodynia: a clinical correlation
Authors: Kenneth Peters
Benjamin Girdler
Donna Carrico
Ibrahim Ibrahim
Ananias Diokno
Publication date: 01-05-2008
Publisher: Springer-Verlag
Published in: International Urogynecology Journal / Issue 5/2008
Print ISSN: 0937-3462
Electronic ISSN: 1433-3023
DOI: https://doi.org/10.1007/s00192-007-0501-y

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Painful bladder syndrome/interstitial cystitis and vulvodynia: a clinical correlation

Abstract

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