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Published in: International Urogynecology Journal 4/2005

01-08-2005 | Original Article

Lower urinary tract symptoms after total and subtotal hysterectomy: results of a randomized controlled trial

Authors: Helga Gimbel, Vibeke Zobbe, Birthe Margrethe Andersen, Thomas Filtenborg, Kristian Jakobsen, Helle Christina Sørensen, Kim Toftager-Larsen, Katrine Sidenius, Nini Møller, Ellen Merete Madsen, Mogens Vejtorp, Helle Clausen, Annie Rosgaard, John Villumsen, Christian Gluud, Bent S. Ottesen, Ann Tabor

Published in: International Urogynecology Journal | Issue 4/2005

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Abstract

The aim of this Danish multicenter trial was to compare the proportion of women with lower urinary tract symptoms after total abdominal hysterectomy (TAH) and subtotal abdominal hysterectomy (SAH) for benign uterine disorders. A total of 319 women were randomized to TAH (n=158) or SAH (n=161). Women were followed up for 1 year by strict data collection procedures, including postal questionnaires. Results were analyzed by intention-to-treat analyses. Urinary incontinence was found less often among TAH women than among SAH women. This was due to a larger reduction of the number of women with stress and urinary incontinence in the TAH group. No other differences were found between the two operation methods. The number of women with urinary incontinence and frequency was reduced from study entry for follow-up, while double/triple voiding was increased. Incontinent women had significantly lower quality of life scores than continent women.
Literature
1.
go back to reference Gimbel H, Settnes A, Tabor A (2001) Hysterectomy on benign indication in Denmark 1988–1998. A register based trend analysis. Acta Obstet Gynecol Scand 80:267–272CrossRefPubMed Gimbel H, Settnes A, Tabor A (2001) Hysterectomy on benign indication in Denmark 1988–1998. A register based trend analysis. Acta Obstet Gynecol Scand 80:267–272CrossRefPubMed
2.
go back to reference Vuorma S, Terperi J, Hurskainen R, Keskimäki I, Kujansuu E (1998) Hysterectomy trends in Finland in 1987–1995—a register based analysis. Acta Obstet Gynecol Scand 77:770–776CrossRefPubMed Vuorma S, Terperi J, Hurskainen R, Keskimäki I, Kujansuu E (1998) Hysterectomy trends in Finland in 1987–1995—a register based analysis. Acta Obstet Gynecol Scand 77:770–776CrossRefPubMed
3.
go back to reference Sills ES, Saini J, Applegate MS, McGee M III, Gretz HF III (1998) Supracervical and total abdominal hysterectomy trends in New York State: 1990–1996. J Urban Health 75:903–910PubMed Sills ES, Saini J, Applegate MS, McGee M III, Gretz HF III (1998) Supracervical and total abdominal hysterectomy trends in New York State: 1990–1996. J Urban Health 75:903–910PubMed
4.
go back to reference Bridgman SA, Dunn KM (2000) Has endometrial ablation replaced hysterectomy for the treatment of dysfunctional uterine bleeding? National figures. Br J Obstet Gynaecol 107:531–534 Bridgman SA, Dunn KM (2000) Has endometrial ablation replaced hysterectomy for the treatment of dysfunctional uterine bleeding? National figures. Br J Obstet Gynaecol 107:531–534
5.
go back to reference Sommer P, Bauer T, Nielsen KK, Kristensen ES, Hermann GG, Steven K et al (1990) Voiding patterns and prevalence of incontinence in women: a questionnaire survey. Br J Urol 66:12–15PubMed Sommer P, Bauer T, Nielsen KK, Kristensen ES, Hermann GG, Steven K et al (1990) Voiding patterns and prevalence of incontinence in women: a questionnaire survey. Br J Urol 66:12–15PubMed
6.
go back to reference Samuelson E, Victor A, Tibblin G (1997) A population study of urinary incontinence and nocturia among women aged 20–59 years: prevalence, well-being and wish for treatment. Acta Obstet Gynecol Scand 76:74–80PubMed Samuelson E, Victor A, Tibblin G (1997) A population study of urinary incontinence and nocturia among women aged 20–59 years: prevalence, well-being and wish for treatment. Acta Obstet Gynecol Scand 76:74–80PubMed
7.
go back to reference Simeonova Z, Milsom I, Kullendorff M, Molander U, Bengtsson C (1999) The prevalence of urinary incontinence and its influence on the quality of life in women from an urban Swedish population. Acta Obstet Gynecol Scand 78:546–551CrossRefPubMed Simeonova Z, Milsom I, Kullendorff M, Molander U, Bengtsson C (1999) The prevalence of urinary incontinence and its influence on the quality of life in women from an urban Swedish population. Acta Obstet Gynecol Scand 78:546–551CrossRefPubMed
8.
9.
go back to reference Milsom I, Ekelund P, Molander U, Arvidsson L, Areskoug B (1993) The influence of age, parity, oral contraception, hysterectomy and menopause on the prevalence of urinary incontinence in women. J Urol 149:1459–1462PubMed Milsom I, Ekelund P, Molander U, Arvidsson L, Areskoug B (1993) The influence of age, parity, oral contraception, hysterectomy and menopause on the prevalence of urinary incontinence in women. J Urol 149:1459–1462PubMed
10.
go back to reference Thom DH, van den Eeden SK, Brown JS (1997) Evaluation of parturition and other reproductive variables as risk factors for urinary incontinence in later life. Obstet Gynecol 90:983–939CrossRefPubMed Thom DH, van den Eeden SK, Brown JS (1997) Evaluation of parturition and other reproductive variables as risk factors for urinary incontinence in later life. Obstet Gynecol 90:983–939CrossRefPubMed
11.
go back to reference Møller LA, Lose G, Jørgensen T (2000) Risk factors for lower urinary tract symptoms in women 40 to 60 years of age. Obstet Gynecol 96:446–451CrossRefPubMed Møller LA, Lose G, Jørgensen T (2000) Risk factors for lower urinary tract symptoms in women 40 to 60 years of age. Obstet Gynecol 96:446–451CrossRefPubMed
12.
go back to reference Mommsen S, Foldspang A (1994) Body mass index and adult female urinary incontinence. World J Urol 12:319–322CrossRefPubMed Mommsen S, Foldspang A (1994) Body mass index and adult female urinary incontinence. World J Urol 12:319–322CrossRefPubMed
13.
go back to reference Brown JS, Seeley DG, Fong J, Black DM, Ensrud KE, Grady D (1996) Urinary incontinence in older women: who is at risk? Study of Osteoporotic Fractures Research Group. Obstet Gynecol 87:715–721CrossRefPubMed Brown JS, Seeley DG, Fong J, Black DM, Ensrud KE, Grady D (1996) Urinary incontinence in older women: who is at risk? Study of Osteoporotic Fractures Research Group. Obstet Gynecol 87:715–721CrossRefPubMed
14.
go back to reference Graham CA, Mallett VT (2001) Race as a predictor of urinary incontinence and pelvic organ prolapse. Am J Obstet Gynecol 185:116–120CrossRefPubMed Graham CA, Mallett VT (2001) Race as a predictor of urinary incontinence and pelvic organ prolapse. Am J Obstet Gynecol 185:116–120CrossRefPubMed
15.
go back to reference Brown JS, Sawaya G, Thorn DH, Grady D (2000) Hysterectomy and urinary incontinence: a systematic review. Lancet 356:535–539CrossRefPubMed Brown JS, Sawaya G, Thorn DH, Grady D (2000) Hysterectomy and urinary incontinence: a systematic review. Lancet 356:535–539CrossRefPubMed
16.
go back to reference Gimbel H, Zobbe V, Andersen BM, Filtenborg T, Gluud C, Tabor A (2003) Danish Hysterectomy Group. Randomised controlled trial of total versus subtotal hysterectomy with one-year follow up results. BJOG 110:1088–1098PubMed Gimbel H, Zobbe V, Andersen BM, Filtenborg T, Gluud C, Tabor A (2003) Danish Hysterectomy Group. Randomised controlled trial of total versus subtotal hysterectomy with one-year follow up results. BJOG 110:1088–1098PubMed
17.
go back to reference Rannestad T, Eikeland O-J, Helland H, Qvarnström U (2001) The quality of life in women suffering from gynecological disorders is improved by means of hysterectomy: absolute and relative differences between pre- and postoperative measures. Acta Obstet Gynecol Scand 80:46–51CrossRefPubMed Rannestad T, Eikeland O-J, Helland H, Qvarnström U (2001) The quality of life in women suffering from gynecological disorders is improved by means of hysterectomy: absolute and relative differences between pre- and postoperative measures. Acta Obstet Gynecol Scand 80:46–51CrossRefPubMed
18.
go back to reference Grimby A, Milsom I, Molander U, Wiklund I, Ekelund P (1993) The influence of urinary incontinence on the quality of life in elderly women. Age Ageing 22:82–89PubMed Grimby A, Milsom I, Molander U, Wiklund I, Ekelund P (1993) The influence of urinary incontinence on the quality of life in elderly women. Age Ageing 22:82–89PubMed
19.
go back to reference Robinson D, Pearce KF, Preisser JS, Dugan E, Suggs PK, Cohen SJ (1998) Relationship between patient reports of urinary incontinence and quality of life measures. Obstet Gynecol 91:224–228CrossRefPubMed Robinson D, Pearce KF, Preisser JS, Dugan E, Suggs PK, Cohen SJ (1998) Relationship between patient reports of urinary incontinence and quality of life measures. Obstet Gynecol 91:224–228CrossRefPubMed
20.
go back to reference Lalos O, Bjerle P (1986) Bladder wall mechanics and micturition before and after subtotal and total hysterectomy. Eur J Obstet Gynecol Reprod Biol 21:143–150CrossRefPubMed Lalos O, Bjerle P (1986) Bladder wall mechanics and micturition before and after subtotal and total hysterectomy. Eur J Obstet Gynecol Reprod Biol 21:143–150CrossRefPubMed
21.
go back to reference Thakar R, Manyonda I, Stanton S, Ayers S, Clarkson P, Robinson G (2002) Outcomes after total versus subtotal abdominal hysterectomy. N Engl J Med 347:1318–1325CrossRefPubMed Thakar R, Manyonda I, Stanton S, Ayers S, Clarkson P, Robinson G (2002) Outcomes after total versus subtotal abdominal hysterectomy. N Engl J Med 347:1318–1325CrossRefPubMed
22.
go back to reference Learman LA, Summitt RL Jr, Varner RE, McNeeley SG, Goodman-Gruen D, Richter HE, Lin F, Showstack J, Ireland CC, Vittinghoff E, Hulley SB, Washington AE et al (2003) A randomized comparison of total or supracervical hysterectomy: surgical complications and clinical outcomes. Obstet Gynecol 102:453–462CrossRefPubMed Learman LA, Summitt RL Jr, Varner RE, McNeeley SG, Goodman-Gruen D, Richter HE, Lin F, Showstack J, Ireland CC, Vittinghoff E, Hulley SB, Washington AE et al (2003) A randomized comparison of total or supracervical hysterectomy: surgical complications and clinical outcomes. Obstet Gynecol 102:453–462CrossRefPubMed
23.
go back to reference Lauridsen L, Jensen VC (1961) Total contra subtotal hysterektomi [Total contra subtotal hysterectomy]. Ugeskr Læger 123:298–307PubMed Lauridsen L, Jensen VC (1961) Total contra subtotal hysterektomi [Total contra subtotal hysterectomy]. Ugeskr Læger 123:298–307PubMed
24.
go back to reference Iosif CS, Bekassy Z, Rydhström H (1988) Prevalence of urinary incontinence in middle-aged women. Int J Gynaecol Obstet 26:255–259CrossRefPubMed Iosif CS, Bekassy Z, Rydhström H (1988) Prevalence of urinary incontinence in middle-aged women. Int J Gynaecol Obstet 26:255–259CrossRefPubMed
25.
go back to reference Kilkku P (1985) Supravaginal uterine amputation versus hysterectomy with reference to subjective bladder symptoms and incontinence. Acta Obstet Gynecol Scand 64:375–379PubMed Kilkku P (1985) Supravaginal uterine amputation versus hysterectomy with reference to subjective bladder symptoms and incontinence. Acta Obstet Gynecol Scand 64:375–379PubMed
26.
go back to reference Kilkku P, Hirvonen T, Gronroos M (1981) Supra-vaginal uterine amputation vs. abdominal hysterectomy: the effect on urinary symptoms with special reference to pollakisuria, nocturia and dysuria. Maturitas 3:197–204PubMed Kilkku P, Hirvonen T, Gronroos M (1981) Supra-vaginal uterine amputation vs. abdominal hysterectomy: the effect on urinary symptoms with special reference to pollakisuria, nocturia and dysuria. Maturitas 3:197–204PubMed
27.
go back to reference Ruoss CF (1995) Supravaginal hysterectomy—a less invasive procedure. J Obstet Gynecol 15:406–409 Ruoss CF (1995) Supravaginal hysterectomy—a less invasive procedure. J Obstet Gynecol 15:406–409
28.
go back to reference Kujansuu E, Teisala K, Punnonen R (1989) Urethral closure function after total and subtotal hysterectomy measured by urethrocystometry. Gynecol Obstet Invest 27:105–106PubMed Kujansuu E, Teisala K, Punnonen R (1989) Urethral closure function after total and subtotal hysterectomy measured by urethrocystometry. Gynecol Obstet Invest 27:105–106PubMed
29.
go back to reference Gimbel H, Zobbe V, Ottesen B, Tabor A (2002) Randomized clinical trial of total versus subtotal hysterectomy: validation of the trial questionnaire. Acta Obstet Gynecol Scand 81:968–974CrossRefPubMed Gimbel H, Zobbe V, Ottesen B, Tabor A (2002) Randomized clinical trial of total versus subtotal hysterectomy: validation of the trial questionnaire. Acta Obstet Gynecol Scand 81:968–974CrossRefPubMed
30.
go back to reference Jackson S, Donovan J, Brookes S, Eckford S, Swithinbank L, Abrams P (1996) The Bristol Female Lower Urinary Tract Symptoms questionnaire: development and psychometric testing. Br J Urol 77:805–812PubMed Jackson S, Donovan J, Brookes S, Eckford S, Swithinbank L, Abrams P (1996) The Bristol Female Lower Urinary Tract Symptoms questionnaire: development and psychometric testing. Br J Urol 77:805–812PubMed
31.
go back to reference Bernstein I, Sejr T, Abel I, Andersen JT, Fischer-Rasmussen W, Klarskov P, Lose G, Madsen H, Mortensen S, Tetzschner T, Walter S (1996) Assessment of lower urinary tract symptoms in women by a self-administered questionnaire: test-retest reliability. Int Urogynecol J Pelvic Floor Dysfunct 7:37–47PubMed Bernstein I, Sejr T, Abel I, Andersen JT, Fischer-Rasmussen W, Klarskov P, Lose G, Madsen H, Mortensen S, Tetzschner T, Walter S (1996) Assessment of lower urinary tract symptoms in women by a self-administered questionnaire: test-retest reliability. Int Urogynecol J Pelvic Floor Dysfunct 7:37–47PubMed
32.
go back to reference Ryhammer AM, Laurberg S, Djurhuus JC, Hermann AP (1998) No relationship between subjective assessment of urinary incontinence and pad test weight gain in a random population sample of menopausal women. J Urol 159:800–803CrossRefPubMed Ryhammer AM, Laurberg S, Djurhuus JC, Hermann AP (1998) No relationship between subjective assessment of urinary incontinence and pad test weight gain in a random population sample of menopausal women. J Urol 159:800–803CrossRefPubMed
33.
go back to reference Simons AM, Yoong WC, Buckland S, Moore KH (2001) Inadequate repeatability of the one-hour pad-test: the need for a new incontinence outcome measure. Br J Obstet Gynaecol 108:315–319CrossRef Simons AM, Yoong WC, Buckland S, Moore KH (2001) Inadequate repeatability of the one-hour pad-test: the need for a new incontinence outcome measure. Br J Obstet Gynaecol 108:315–319CrossRef
34.
go back to reference Homma Y, Ando T, Yoshida M, Kageyama S, Takei M, Kimto K, Ishizuka O, Gotoh M, Hashimoto T (2002) Voiding and incontinence frequencies: variability of diary data and required diary length. Neurourol Urodyn 23:204–209CrossRef Homma Y, Ando T, Yoshida M, Kageyama S, Takei M, Kimto K, Ishizuka O, Gotoh M, Hashimoto T (2002) Voiding and incontinence frequencies: variability of diary data and required diary length. Neurourol Urodyn 23:204–209CrossRef
35.
go back to reference Summit RL, Bent AE (1996) Genuine stress incontinence: an overview. In: Ostergaard DR, Bent AE (eds) Urogynecology and urodynamics. Theory and practice. Williams and Wilkins, Baltimore, pp 493–505 Summit RL, Bent AE (1996) Genuine stress incontinence: an overview. In: Ostergaard DR, Bent AE (eds) Urogynecology and urodynamics. Theory and practice. Williams and Wilkins, Baltimore, pp 493–505
36.
go back to reference Mouritsen L, Rasmussen A (1993) Bladder neck mobility evaluated by vaginal ultrasonography. Br J Urol 7:166–171 Mouritsen L, Rasmussen A (1993) Bladder neck mobility evaluated by vaginal ultrasonography. Br J Urol 7:166–171
37.
go back to reference Käser O, Iklé FA, Hirsch HA (1985) Atlas of gynecological surgery. Georg Thieme Verlag, Stuttgart, p 7.4 Käser O, Iklé FA, Hirsch HA (1985) Atlas of gynecological surgery. Georg Thieme Verlag, Stuttgart, p 7.4
38.
go back to reference Demirci F, Ozden S, Alpay Z, Demirci ET (1999) The effect of abdominal hysterectomy on bladder neck and urinary incontinence. Aust N Z J Obstet Gynecol 39:239–242 Demirci F, Ozden S, Alpay Z, Demirci ET (1999) The effect of abdominal hysterectomy on bladder neck and urinary incontinence. Aust N Z J Obstet Gynecol 39:239–242
39.
go back to reference Penttinen J, Lindholm EL, Kaar K, Kauppila A (1989) Successful colposuspension in stress incontinence reduces bladder neck mobility and increases pressure transmission to the urethra. Arch Gynecol Obstet 244:233–238CrossRefPubMed Penttinen J, Lindholm EL, Kaar K, Kauppila A (1989) Successful colposuspension in stress incontinence reduces bladder neck mobility and increases pressure transmission to the urethra. Arch Gynecol Obstet 244:233–238CrossRefPubMed
40.
go back to reference Mouritsen L (2001) Effect of vaginal devices on bladder neck mobility in stress incontinent women. Acta Obstet Gynecol Scand 80:428PubMed Mouritsen L (2001) Effect of vaginal devices on bladder neck mobility in stress incontinent women. Acta Obstet Gynecol Scand 80:428PubMed
41.
go back to reference Haylen BT, Law MG, Frazer M, Schulz S (1999) Urine flow rates and residual urine volumes in urogynecology patients. Int Urogynecol J Pelvic Floor Dysfunct 10:378–383CrossRefPubMed Haylen BT, Law MG, Frazer M, Schulz S (1999) Urine flow rates and residual urine volumes in urogynecology patients. Int Urogynecol J Pelvic Floor Dysfunct 10:378–383CrossRefPubMed
Metadata
Title
Lower urinary tract symptoms after total and subtotal hysterectomy: results of a randomized controlled trial
Authors
Helga Gimbel
Vibeke Zobbe
Birthe Margrethe Andersen
Thomas Filtenborg
Kristian Jakobsen
Helle Christina Sørensen
Kim Toftager-Larsen
Katrine Sidenius
Nini Møller
Ellen Merete Madsen
Mogens Vejtorp
Helle Clausen
Annie Rosgaard
John Villumsen
Christian Gluud
Bent S. Ottesen
Ann Tabor
Publication date
01-08-2005
Publisher
Springer-Verlag
Published in
International Urogynecology Journal / Issue 4/2005
Print ISSN: 0937-3462
Electronic ISSN: 1433-3023
DOI
https://doi.org/10.1007/s00192-005-1291-8

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