Skip to main content
Top
Published in: Knee Surgery, Sports Traumatology, Arthroscopy 11/2014

01-11-2014 | Knee

Treatment for Staphylococcus aureus infection following open wedge high tibial osteotomy using antibiotic-impregnated calcium phosphate cement

Authors: Kazushige Seki, Akihito Sakka, Atsunori Tokushige, Takashi Imagama, Masanori Mutou, Toshihiko Taguchi

Published in: Knee Surgery, Sports Traumatology, Arthroscopy | Issue 11/2014

Login to get access

Abstract

This report describes a case of Staphylococcus aureus infection following open wedge high tibial osteotomy, which was successfully treated with by implant removal and replacement with antibiotic-impregnated calcium phosphate cement along with external fixation. The infection occurred 7 months after primary surgery and was treated by implant removal, debridement, external fixation, and application of vancomycin impregnated calcium phosphate cement to fill the defect. Subsequently, the infection resolved completely, and the osteotomy healed with no correction loss. Compared with conventional bone cement, calcium phosphate cement might be an optimal material for certain cases of infection after open wedge high tibial osteotomy because of its higher antibiotic retention, biocompatibility, osteoconductivity, and compatibility with heatlabile antibiotics.
Level of evidence V.
Literature
1.
go back to reference Chae DJ, Shetty GM, Wang KH, Montalban AS Jr, Kim JI, Nha KW (2011) Early complications of medial opening wedge high tibial osteotomy using autologous tricortical iliac bone graft and T-plate fixation. Knee 18:278–284PubMedCrossRef Chae DJ, Shetty GM, Wang KH, Montalban AS Jr, Kim JI, Nha KW (2011) Early complications of medial opening wedge high tibial osteotomy using autologous tricortical iliac bone graft and T-plate fixation. Knee 18:278–284PubMedCrossRef
2.
go back to reference Dewilde TR, Dauw J, Vandenneucker H, Bellemans J (2013) Opening wedge distal femoral varus osteotomy using the Puddu plate and calcium phosphate bone cement. Knee Surg Sports Traumatol Arthrosc 21:249–254PubMedCrossRef Dewilde TR, Dauw J, Vandenneucker H, Bellemans J (2013) Opening wedge distal femoral varus osteotomy using the Puddu plate and calcium phosphate bone cement. Knee Surg Sports Traumatol Arthrosc 21:249–254PubMedCrossRef
3.
go back to reference Hidaka N, Yamano Y, Kadoya Y, Nishimura N (2002) Calcium phosphate bone cement for treatment of distal radius fractures: a preliminary report. J Orthop Sci 7:182–187PubMedCrossRef Hidaka N, Yamano Y, Kadoya Y, Nishimura N (2002) Calcium phosphate bone cement for treatment of distal radius fractures: a preliminary report. J Orthop Sci 7:182–187PubMedCrossRef
4.
go back to reference Ivarsson I, Myrnerts R, Gilquist J (1990) High tibial osteotomy for medial osteoarthritis of the knee. A 5–7 and an 11–13 year follow-up. J Bone Joint Surg Br 72:238–244PubMed Ivarsson I, Myrnerts R, Gilquist J (1990) High tibial osteotomy for medial osteoarthritis of the knee. A 5–7 and an 11–13 year follow-up. J Bone Joint Surg Br 72:238–244PubMed
5.
go back to reference Jenny K, Jenny H, Morscher E (1985) Indications surgical technic and results of transcondylar tibia osteotomy in gonarthrosis. Experiences based on a follow-up study of 783 tibia osteotomies. Orthopade 14:161–171PubMed Jenny K, Jenny H, Morscher E (1985) Indications surgical technic and results of transcondylar tibia osteotomy in gonarthrosis. Experiences based on a follow-up study of 783 tibia osteotomies. Orthopade 14:161–171PubMed
6.
go back to reference Koshino T (1982) The treatment of spontaneous osteonecrosis of the knee by high tibial osteotomy with and without bone grafting or drilling of the lesion. J Bone Joint Surg Am 64:47–58PubMed Koshino T (1982) The treatment of spontaneous osteonecrosis of the knee by high tibial osteotomy with and without bone grafting or drilling of the lesion. J Bone Joint Surg Am 64:47–58PubMed
7.
go back to reference Lazarettos J, Efstathopoulos N, Papagelopoulos PJ, Savvidou OD, Kanellakopoulou K, Giamarellou H, Giamarellos-Bourboulis EJ, Nikolaou V, Kapranou A, Papalois A, Papachristou G (2004) A bioresorbable calcium phosphate delivery system with teicoplanin for treating MRSA osteomyelitis. Clin Orthop Relat Res 423:253–258PubMedCrossRef Lazarettos J, Efstathopoulos N, Papagelopoulos PJ, Savvidou OD, Kanellakopoulou K, Giamarellou H, Giamarellos-Bourboulis EJ, Nikolaou V, Kapranou A, Papalois A, Papachristou G (2004) A bioresorbable calcium phosphate delivery system with teicoplanin for treating MRSA osteomyelitis. Clin Orthop Relat Res 423:253–258PubMedCrossRef
8.
go back to reference Magyar G, Ahl TL, Vibe P, Toksvig-Larsen S, Lindstrand A (1999) Open-wedge osteotomy by hemicallotasis or the closed-wedge technique for osteoarthritis of the knee. A randomized study of 50 operations. J Bone Joint Surg Br 81:444–448PubMedCrossRef Magyar G, Ahl TL, Vibe P, Toksvig-Larsen S, Lindstrand A (1999) Open-wedge osteotomy by hemicallotasis or the closed-wedge technique for osteoarthritis of the knee. A randomized study of 50 operations. J Bone Joint Surg Br 81:444–448PubMedCrossRef
9.
go back to reference Reischl N, Wahl P, Jacobi M, Clerc S, Gautier E, Jakob RP (2009) Infections after high tibial open wedge osteotomy: a case control study. Arch Orthop Trauma Surg 129:1483–1487PubMedCrossRef Reischl N, Wahl P, Jacobi M, Clerc S, Gautier E, Jakob RP (2009) Infections after high tibial open wedge osteotomy: a case control study. Arch Orthop Trauma Surg 129:1483–1487PubMedCrossRef
10.
go back to reference Sasaki T, Ishibashi Y, Katano H, Nagumo A, Toh S (2005) In vitro elution of vancomycin from calcium phosphate cement. J Arthroplasty 20:1055–1059PubMedCrossRef Sasaki T, Ishibashi Y, Katano H, Nagumo A, Toh S (2005) In vitro elution of vancomycin from calcium phosphate cement. J Arthroplasty 20:1055–1059PubMedCrossRef
11.
go back to reference Song EK, Seon JK, Park SJ, Jeong MS (2010) The complications of high tibial osteotomy. Closing-versus opening-wedge methods. J Bone Joint Surg Br 92:1245–1252PubMedCrossRef Song EK, Seon JK, Park SJ, Jeong MS (2010) The complications of high tibial osteotomy. Closing-versus opening-wedge methods. J Bone Joint Surg Br 92:1245–1252PubMedCrossRef
12.
go back to reference Spahn G (2003) Complications in high tibial (medial opening wedge) osteotomy. Arch Orthop Trauma Surg 124:649–653PubMedCrossRef Spahn G (2003) Complications in high tibial (medial opening wedge) osteotomy. Arch Orthop Trauma Surg 124:649–653PubMedCrossRef
13.
go back to reference Staubli AE, De Simoni C, Babst R, Lobenhoffer P (2003) TomoFix: a new LCP-concept for open wedge osteotomy of the medial proximal tibia—early results in 92 cases. Injury 34(Suppl 2):55–62CrossRef Staubli AE, De Simoni C, Babst R, Lobenhoffer P (2003) TomoFix: a new LCP-concept for open wedge osteotomy of the medial proximal tibia—early results in 92 cases. Injury 34(Suppl 2):55–62CrossRef
14.
go back to reference Takahashi T, Wada Y, Tanaka M, Iwagawa M, Ikeuchi M, Hirose D, Yamamoto H (2000) Dome-shaped proximal tibial osteotomy using percutaneous drilling for osteoarthritis of the knee. Arch Orthop Trauma Surg 120:32–37PubMed Takahashi T, Wada Y, Tanaka M, Iwagawa M, Ikeuchi M, Hirose D, Yamamoto H (2000) Dome-shaped proximal tibial osteotomy using percutaneous drilling for osteoarthritis of the knee. Arch Orthop Trauma Surg 120:32–37PubMed
15.
go back to reference Urabe K, Naruse K, Hattori H, Hirano M, Uchida K, Onuma K, Park HJ, Itoman M (2009) In vitro comparison of elution characteristics of vancomycin from calcium phosphate cement and polymethylmethacrylate. J Orthop Sci 14:784–793PubMedCrossRef Urabe K, Naruse K, Hattori H, Hirano M, Uchida K, Onuma K, Park HJ, Itoman M (2009) In vitro comparison of elution characteristics of vancomycin from calcium phosphate cement and polymethylmethacrylate. J Orthop Sci 14:784–793PubMedCrossRef
16.
go back to reference Valkering KP, van de Bekerom MP, Kappelhoff FM, Albers GH (2009) Complications after tomofix medial opening wedge high tibial osteotomy. J Knee Surg 22:218–225PubMedCrossRef Valkering KP, van de Bekerom MP, Kappelhoff FM, Albers GH (2009) Complications after tomofix medial opening wedge high tibial osteotomy. J Knee Surg 22:218–225PubMedCrossRef
17.
go back to reference Viskontas DG, MacLeod MD, Sanders DW (2006) High tibial osteotomy with use of the Taylor Spatial Frame external fixator for osteoarthritis of the knee. Can J Surg 49:245–250PubMedPubMedCentral Viskontas DG, MacLeod MD, Sanders DW (2006) High tibial osteotomy with use of the Taylor Spatial Frame external fixator for osteoarthritis of the knee. Can J Surg 49:245–250PubMedPubMedCentral
Metadata
Title
Treatment for Staphylococcus aureus infection following open wedge high tibial osteotomy using antibiotic-impregnated calcium phosphate cement
Authors
Kazushige Seki
Akihito Sakka
Atsunori Tokushige
Takashi Imagama
Masanori Mutou
Toshihiko Taguchi
Publication date
01-11-2014
Publisher
Springer Berlin Heidelberg
Published in
Knee Surgery, Sports Traumatology, Arthroscopy / Issue 11/2014
Print ISSN: 0942-2056
Electronic ISSN: 1433-7347
DOI
https://doi.org/10.1007/s00167-013-2460-9

Other articles of this Issue 11/2014

Knee Surgery, Sports Traumatology, Arthroscopy 11/2014 Go to the issue