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Knee Surgery, Sports Traumatology, Arthroscopy

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01-01-2014 | Knee

The effects of defect size, orientation, and location on subchondral bone contact in oval-shaped experimental articular cartilage defects in a bovine knee model

Authors: David C. Flanigan, Joshua D. Harris, Peter M. Brockmeier, Rebecca L. Lathrop, Robert A. Siston

Published in: Knee Surgery, Sports Traumatology, Arthroscopy | Issue 1/2014

Abstract

Purpose

Chondral defects of the knee may lead to pain and disability, often requiring surgical intervention. The purpose of this study was to identify how size, location, and orientation influences subchondral bone contact within oval-shaped chondral defects.

Methods

Full-thickness defects were created in twelve bovine knees. Defect orientation was randomized between coronal and sagittal planes on both the medial and lateral femoral condyles (MFC and LFC). In extension, knees were statically loaded to 1,000 N. Area measurements were recorded using Tekscan sensors and I-Scan software. A MATLAB program computed defect area and the area within the defect demonstrating subchondral bone contact.

Results

Defect area, location, and orientation each had a significant effect on subchondral bone contact (p < 0.001), and significant interactions were found between defect area and both location and orientation. The size threshold (cm²) at which significant contact occurred on the subchondral bone within the defect was smallest for LFC/coronal defects (0.73 cm²), then LFC/sagittal (1.14 cm²), then MFC/coronal (1.61 cm²), and then MFC/sagittal (no threshold reached).

Conclusions

Intra-articular location and orientation of a femoral condyle chondral defect, in addition to area, significantly influence femoral subchondral bone contact within the defect and the threshold at which subchondral bone contact occurs within the defect. The parameters of defect location and shape orientation supplement current surgical algorithms to manage knee articular cartilage surgery. This may indicate different cartilage restorative procedures based on the effect on the subchondral bone from the defect geometry itself and the selected cartilage surgery.

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Title: The effects of defect size, orientation, and location on subchondral bone contact in oval-shaped experimental articular cartilage defects in a bovine knee model
Authors: David C. Flanigan
Joshua D. Harris
Peter M. Brockmeier
Rebecca L. Lathrop
Robert A. Siston
Publication date: 01-01-2014
Publisher: Springer Berlin Heidelberg
Published in: Knee Surgery, Sports Traumatology, Arthroscopy / Issue 1/2014
Print ISSN: 0942-2056
Electronic ISSN: 1433-7347
DOI: https://doi.org/10.1007/s00167-012-2342-6

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The effects of defect size, orientation, and location on subchondral bone contact in oval-shaped experimental articular cartilage defects in a bovine knee model

Abstract

Purpose

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusions

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