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Knee Surgery, Sports Traumatology, Arthroscopy

Published in:

01-05-2012 | Knee

Patellofemoral and tibiofemoral articular cartilage and subchondral bone health following arthroscopic partial medial meniscectomy

Authors: Yuanyuan Wang, Alasdair R. Dempsey, David G. Lloyd, Peter M. Mills, Tim Wrigley, Kim L. Bennell, Ben Metcalf, Fahad Hanna, Flavia M. Cicuttini

Published in: Knee Surgery, Sports Traumatology, Arthroscopy | Issue 5/2012

Abstract

Purpose

To examine articular cartilage and subchondral bone changes in tibiofemoral and patellofemoral joints following partial medial meniscectomy.

Methods

For this cross-sectional study, 158 patients aged 30–55 years, without evidence of knee osteoarthritis at arthroscopic partial medial meniscectomy (APMM), and 38 controls were recruited. MRI was performed once on the operated knee for each subcohort of 3 months, 2 or 4 years post-surgery, and the randomly assigned knee of the controls. Cartilage volume, cartilage defects, and bone size were assessed using validated methods.

Results

Compared with controls, APMM patients had more prevalent cartilage defects in medial tibiofemoral (OR = 3.17, 95%CI 1.24–8.11) and patellofemoral (OR = 13.76, 95%CI 1.52–124.80) compartments, and increased medial tibial plateau bone area (B = 143.8, 95%CI 57.4–230.2). Time from APMM was positively associated with cartilage defect prevalence in medial tibiofemoral (OR = 1.02, 95%CI 1.00–1.03) and patellofemoral (OR = 1.04, 95%CI 1.01–1.07) compartments, and medial tibial plateau area (B = 2.5, 95%CI 0.8–4.3), but negatively associated with lateral tibial cartilage volume (B = −4.9, 95%CI −8.4 to −1.5). The association of APMM and time from APMM with patellar cartilage defects was independent of tibial cartilage volume.

Conclusions

Partial medial meniscectomy is associated with adverse effects on articular cartilage and subchondral bone, which are associated with subsequent osteoarthritis, in both tibiofemoral and patellofemoral compartments.

Level of evidence

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Title: Patellofemoral and tibiofemoral articular cartilage and subchondral bone health following arthroscopic partial medial meniscectomy
Authors: Yuanyuan Wang
Alasdair R. Dempsey
David G. Lloyd
Peter M. Mills
Tim Wrigley
Kim L. Bennell
Ben Metcalf
Fahad Hanna
Flavia M. Cicuttini
Publication date: 01-05-2012
Publisher: Springer-Verlag
Published in: Knee Surgery, Sports Traumatology, Arthroscopy / Issue 5/2012
Print ISSN: 0942-2056
Electronic ISSN: 1433-7347
DOI: https://doi.org/10.1007/s00167-011-1681-z

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Patellofemoral and tibiofemoral articular cartilage and subchondral bone health following arthroscopic partial medial meniscectomy

Abstract

Purpose

Methods

Results

Conclusions

Level of evidence

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusions

Level of evidence

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