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Appendix
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Literature
1.
go back to reference Cook JA et al (2018) DELTA(2) guidance on choosing the target difference and undertaking and reporting the sample size calculation for a randomised controlled trial. BMJ 363:k3750CrossRef Cook JA et al (2018) DELTA(2) guidance on choosing the target difference and undertaking and reporting the sample size calculation for a randomised controlled trial. BMJ 363:k3750CrossRef
2.
go back to reference Scales DC, Rubenfeld GD (2005) Estimating sample size in critical care clinical trials. J Crit Care 20(1):6–11CrossRef Scales DC, Rubenfeld GD (2005) Estimating sample size in critical care clinical trials. J Crit Care 20(1):6–11CrossRef
3.
go back to reference Stanski NL, Wong HR (2020) Prognostic and predictive enrichment in sepsis. Nat Rev Nephrol 16(1):20–31CrossRef Stanski NL, Wong HR (2020) Prognostic and predictive enrichment in sepsis. Nat Rev Nephrol 16(1):20–31CrossRef
4.
go back to reference Evans L et al (2021) Surviving sepsis campaign: international guidelines for management of sepsis and septic shock 2021. Intensive Care Med 47:1181–1247CrossRef Evans L et al (2021) Surviving sepsis campaign: international guidelines for management of sepsis and septic shock 2021. Intensive Care Med 47:1181–1247CrossRef
5.
go back to reference Cohen J et al (2015) Sepsis: a roadmap for future research. Lancet Infect Dis 15(5):581–614CrossRef Cohen J et al (2015) Sepsis: a roadmap for future research. Lancet Infect Dis 15(5):581–614CrossRef
Metadata
Title
Characterizing systematic challenges in sample size determination for sepsis trials
Authors
Alexandre Tran
Shannon M. Fernando
Bram Rochwerg
Christopher W. Seymour
Deborah J. Cook
Publication date
12-04-2022
Publisher
Springer Berlin Heidelberg
Published in
Intensive Care Medicine / Issue 6/2022
Print ISSN: 0342-4642
Electronic ISSN: 1432-1238
DOI
https://doi.org/10.1007/s00134-022-06691-4

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