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Intensive Care Medicine

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01-02-2019 | Letter

Mechanism of airway closure in acute respiratory distress syndrome: a possible role of surfactant depletion

Authors: Remi Coudroy, Cong Lu, Lu Chen, Alexandre Demoule, Laurent Brochard

Published in: Intensive Care Medicine | Issue 2/2019

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Chen L, Del Sorbo L, Grieco DL et al (2018) Airway closure in acute respiratory distress syndrome: an underestimated and misinterpreted phenomenon. Am J Respir Crit Care Med 197:132–136. https://doi.org/10.1164/rccm.201702-0388LE CrossRefPubMed

Demoule A, Decailliot F, Jonson B et al (2006) Relationship between pressure-volume curve and markers for collagen turn-over in early acute respiratory distress syndrome. Intensive Care Med 32:413–420. https://doi.org/10.1007/s00134-005-0043-z CrossRefPubMed

Attalah HL, Wu Y, Alaoui-El-Azher M et al (2003) Induction of type-IIA secretory phospholipase A2 in animal models of acute lung injury. Eur Respir J 21:1040–1045CrossRefPubMed

Hughes JM, Rosenzweig DY, Kivitz PB (1970) Site of airway closure in excised dog lungs: histologic demonstration. J Appl Physiol 29:340–344. https://doi.org/10.1152/jappl.1970.29.3.340 CrossRefPubMed

Yonis H, Mortaza S, Baboi L et al (2018) Expiratory flow limitation assessment in patients with acute respiratory distress syndrome. A reappraisal. Am J Respir Crit Care Med 198:131–134. https://doi.org/10.1164/rccm.201711-2326LE CrossRefPubMed

Title: Mechanism of airway closure in acute respiratory distress syndrome: a possible role of surfactant depletion
Authors: Remi Coudroy
Cong Lu
Lu Chen
Alexandre Demoule
Laurent Brochard
Publication date: 01-02-2019
Publisher: Springer Berlin Heidelberg
Published in: Intensive Care Medicine / Issue 2/2019
Print ISSN: 0342-4642
Electronic ISSN: 1432-1238
DOI: https://doi.org/10.1007/s00134-018-5501-5

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Mechanism of airway closure in acute respiratory distress syndrome: a possible role of surfactant depletion

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