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01-12-2018 | Editorial

Benefits and risks of the P/F approach

Authors: L. Gattinoni, F. Vassalli, F. Romitti

Published in: Intensive Care Medicine | Issue 12/2018

Excerpt

The PaO₂/FIO₂ ratio represents the pressure exerted in the blood by the unbound molecules of oxygen, normalized to the fractional volume of inspired oxygen. The PaO₂/FIO₂ ratio is used to assess the lung’s capability to oxygenate the blood, primarily in ARDS, where its thresholds of 150, 200, and 300 are used/proposed to classify ARDS severity [1, 2]. Ideally, a given PaO₂/FIO₂ ratio value should correspond to a definite lung severity, independently of FIO₂. In reality, the same severity may be associated with quite different PaO₂/FIO₂ values, depending on several factors, as previously described [3]. …

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Title: Benefits and risks of the P/F approach
Authors: L. Gattinoni
F. Vassalli
F. Romitti
Publication date: 01-12-2018
Publisher: Springer Berlin Heidelberg
Published in: Intensive Care Medicine / Issue 12/2018
Print ISSN: 0342-4642
Electronic ISSN: 1432-1238
DOI: https://doi.org/10.1007/s00134-018-5413-4

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