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Published in: Intensive Care Medicine 3/2017

01-03-2017 | Editorial

Should all patients with sepsis receive anticoagulation? Yes

Authors: Ferhat Meziani, Satoshi Gando, Jean-Louis Vincent

Published in: Intensive Care Medicine | Issue 3/2017

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Excerpt

Sepsis is invariably associated with activation of blood coagulation owing to excessive thrombin formation, defective fibrinolysis and defective natural anticoagulants, resulting in fibrin deposits and ultimately in disseminated intravascular coagulation (DIC) [1]. Furthermore, as a result of microvascular thrombosis, sepsis-induced coagulopathy has been associated with multiple organ dysfunction syndrome and a poor prognosis [2]. This represents the basis for anticoagulation in all patients with sepsis. …
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Metadata
Title
Should all patients with sepsis receive anticoagulation? Yes
Authors
Ferhat Meziani
Satoshi Gando
Jean-Louis Vincent
Publication date
01-03-2017
Publisher
Springer Berlin Heidelberg
Published in
Intensive Care Medicine / Issue 3/2017
Print ISSN: 0342-4642
Electronic ISSN: 1432-1238
DOI
https://doi.org/10.1007/s00134-016-4621-z

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