Published in:
01-03-2017 | Editorial
Should all patients with sepsis receive anticoagulation? Yes
Authors:
Ferhat Meziani, Satoshi Gando, Jean-Louis Vincent
Published in:
Intensive Care Medicine
|
Issue 3/2017
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Excerpt
Sepsis is invariably associated with activation of blood coagulation owing to excessive thrombin formation, defective fibrinolysis and defective natural anticoagulants, resulting in fibrin deposits and ultimately in disseminated intravascular coagulation (DIC) [
1]. Furthermore, as a result of microvascular thrombosis, sepsis-induced coagulopathy has been associated with multiple organ dysfunction syndrome and a poor prognosis [
2]. This represents the basis for anticoagulation in all patients with sepsis. …