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01-11-2016 | Understanding the Disease

Understanding the venous–arterial CO₂ to arterial–venous O₂ content difference ratio

Authors: Gustavo A. Ospina-Tascón, Glenn Hernández, Maurizio Cecconi

Published in: Intensive Care Medicine | Issue 11/2016

Excerpt

Early identification of tissue hypoperfusion is a cornerstone of shock management [1]. Normal macrohemodynamic and oxygen-derived parameters do not, however, rule out the presence of tissue hypoxia [2]. In this setting, carbon dioxide (CO₂)-derived variables may provide information on macro- and microvascular blood flow [3] and also on the presence of anaerobic metabolism [4, 5]. Importantly, variations in CO₂ occur more rapidly than changes in lactate kinetics, making the former an attractive biomarker for monitoring, especially during the early stages of resuscitation [6, 7]. …

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Title: Understanding the venous–arterial CO2 to arterial–venous O2 content difference ratio
Authors: Gustavo A. Ospina-Tascón
Glenn Hernández
Maurizio Cecconi
Publication date: 01-11-2016
Publisher: Springer Berlin Heidelberg
Published in: Intensive Care Medicine / Issue 11/2016
Print ISSN: 0342-4642
Electronic ISSN: 1432-1238
DOI: https://doi.org/10.1007/s00134-016-4233-7

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Understanding the venous–arterial CO₂ to arterial–venous O₂ content difference ratio

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Keynote webinar | Spotlight on medication adherence

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