Published in:
01-12-2016 | Understanding the Disease
Understanding why resistant bacteria are associated with higher mortality in ICU patients
Authors:
François Barbier, Thiago Lisboa, Saad Nseir
Published in:
Intensive Care Medicine
|
Issue 12/2016
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Excerpt
The incidence of infections related to multidrug-resistant (MDR) bacteria is high in the ICU. Based on the results of the large multinational EPIC II study, MDR bacteria represented 36 % of microorganisms identified in patients with confirmed infection [
1]. The main risk factors for resistance are prior exposure to antibiotics, prolonged hospital and ICU length of stay (LOS), invasive devices, comorbidities and local epidemiology [
2‐
4]. …