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Intensive Care Medicine
Published in: Intensive Care Medicine 8/2011

01-08-2011 | Physiological and Technical Notes

Lung sound analysis correlates to injury and recruitment as identified by computed tomography: an experimental study

Authors: Antonio Vena, Christian Rylander, Gaetano Perchiazzi, Rocco Giuliani, Göran Hedenstierna

Published in: Intensive Care Medicine | Issue 8/2011

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Abstract

Purpose

The aim of this study is to assess how analysis of the spectral characteristics of lung sounds can help in detecting lung injury and subsequent recruitment as verified by computed tomography (CT).

Methods

Lung sounds were recorded at four locations (ventral and dorsal on right and left side) in six ventilated pigs before and after unilateral oleic acid-induced lung injury during sequential increase of positive end-expiratory pressure (PEEP) from 0 to 20 cmH2O. CT scans of the chest were used for comparison with lung aeration. Sound characteristics were compared by computer-aided analysis in the time and frequency domain as well as by clinicians.

Results

The presence of lung injury and its location were detected by substantial acoustic spectral components above 500 Hz (frequency) and −70 dB (amplitude). Application of increasing PEEP gradually reduced the pathological components as CT analysis verified recruitment. At 20 cmH2O PEEP there was no further tidal recruitment of injured lung and the pathological sounds had disappeared, rendering the lung sounds of the injured lung similar to those of the control lung. This was mirrored by the clinicians’ characterization of the sounds.

Conclusions

Computer-aided analysis of lung sounds is suitable for detection of pathological lung sounds and may guide in detection and recruitment of poorly/nonaerated lung.
Appendix
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Metadata
Title
Lung sound analysis correlates to injury and recruitment as identified by computed tomography: an experimental study
Authors
Antonio Vena
Christian Rylander
Gaetano Perchiazzi
Rocco Giuliani
Göran Hedenstierna
Publication date
01-08-2011
Publisher
Springer-Verlag
Published in
Intensive Care Medicine / Issue 8/2011
Print ISSN: 0342-4642
Electronic ISSN: 1432-1238
DOI
https://doi.org/10.1007/s00134-011-2291-4

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