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Intensive Care Medicine
Published in: Intensive Care Medicine 7/2011

01-07-2011 | Editorial

The brain–lung–brain axis

Authors: Robert D. Stevens, Louis Puybasset

Published in: Intensive Care Medicine | Issue 7/2011

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Excerpt

Severe neurological dysfunction and injury are associated with a propensity to develop concurrent pulmonary edema and lung injury which can further worsen clinical outcomes [1]. This has been observed in a range of settings including traumatic brain injury [2], aneurysmal subarachnoid hemorrhage [3], status epilepticus [4], and in brain death [5]. More recently, studies have shown that critical pulmonary disorders such as acute lung injury and acute respiratory distress syndrome (ALI/ARDS) may be responsible for brain injury and poor neurocognitive outcomes [6, 7]. While the implications of these findings are considerable, the underlying biological mechanisms need clarification. …
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Metadata
Title
The brain–lung–brain axis
Authors
Robert D. Stevens
Louis Puybasset
Publication date
01-07-2011
Publisher
Springer-Verlag
Published in
Intensive Care Medicine / Issue 7/2011
Print ISSN: 0342-4642
Electronic ISSN: 1432-1238
DOI
https://doi.org/10.1007/s00134-011-2233-1

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