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Intensive Care Medicine

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01-05-2009 | Review

Depression in general intensive care unit survivors: a systematic review

Authors: Dimitry S. Davydow, Jeneen M. Gifford, Sanjay V. Desai, O. Joseph Bienvenu, Dale M. Needham

Published in: Intensive Care Medicine | Issue 5/2009

Abstract

Purpose

To critically review data on the prevalence of depressive symptoms in general intensive care unit (ICU) survivors, risk factors for these symptoms, and their impact on health-related quality of life (HRQOL).

Methods

We conducted a systematic review using Medline, EMBASE, Cochrane Library, CINAHL, PsycINFO, and a hand-search of 13 journals.

Results

Fourteen studies were eligible. The median point prevalence of “clinically significant” depressive symptoms was 28% (total n = 1,213). Neither sex nor age were consistent risk factors for post-ICU depression, and severity of illness at ICU admission was consistently not a risk factor. Early post-ICU depressive symptoms were a strong risk factor for subsequent depressive symptoms. Post-ICU depressive symptoms were associated with substantially lower HRQOL.

Conclusions

Depressive symptoms are common in general ICU survivors and negatively impact HRQOL. Future studies should address how factors related to individual patients, critical illness and post-ICU recovery are associated with depression in ICU survivors.

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Title: Depression in general intensive care unit survivors: a systematic review
Authors: Dimitry S. Davydow
Jeneen M. Gifford
Sanjay V. Desai
O. Joseph Bienvenu
Dale M. Needham
Publication date: 01-05-2009
Publisher: Springer-Verlag
Published in: Intensive Care Medicine / Issue 5/2009
Print ISSN: 0342-4642
Electronic ISSN: 1432-1238
DOI: https://doi.org/10.1007/s00134-009-1396-5

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Depression in general intensive care unit survivors: a systematic review

Abstract

Purpose

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusions

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