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01-06-2008 | Physiological and Technical Notes

Inductive plethysmography to control volume-targeted ventilation for leak compensation

Authors: Marie Claire Andrieu, Cedric Quentin, David Orlikowski, Gilbert Desmarais, Daniel Isabey, Bruno Louis, Frédéric Lofaso

Published in: Intensive Care Medicine | Issue 6/2008

Abstract

Objective

Volume-targeted ventilation is associated with poor compensation for leaks yet is frequently used in neuromuscular patients, many of whom experience mouth leaks. Our objective was to test the feasibility and efficacy of a prototype ventilator designed to achieve leak compensation by feed-back control of the actual tidal volume based on either the volume blown to the expiratory circuit (VTEVC-compensation) or the tidal volume measured by inductive plethysmography (VTplet-compensation).

Design and setting

Randomized, cross-over, physiological study in a physiological ward of a university teaching hospital.

Participants

Nine normal individuals.

Intervention

Subjects tested volume-targeted assist-control ventilation without compensation, with VTEVC-compensation, and with VTplet-compensation. Tests were done with the mouth closed, with mouth leaks during inspiration, and with mouth leaks during expiration.

Measurements and results

With inspiratory mouth leaks compared to mouth closed, the delivered volume remained unchanged without leak compensation, increased to 143 ± 30% with VTEVC-compensation, and increased to 132 ± 17% with VTplet-compensation; the expired tidal volume decreased to 46 ± 24% without compensation, 66 ± 20% with VTEVC-compensation, and 68 ± 23% with VTplet-compensation. With expiratory mouth leaks, the ventilator-delivered volume and expired tidal volume were unchanged with no compensation and with VTplet-compensation; they increased with VTEVC-compensation.

Conclusion

Leak compensation can be achieved during volume-targeted ventilation. VTEVC-compensation and VTplet-compensation were equally effective in compensating for inspiratory leaks, and VTplet-compensation also performed well when expiratory leaks occurred.

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Title: Inductive plethysmography to control volume-targeted ventilation for leak compensation
Authors: Marie Claire Andrieu
Cedric Quentin
David Orlikowski
Gilbert Desmarais
Daniel Isabey
Bruno Louis
Frédéric Lofaso
Publication date: 01-06-2008
Publisher: Springer-Verlag
Published in: Intensive Care Medicine / Issue 6/2008
Print ISSN: 0342-4642
Electronic ISSN: 1432-1238
DOI: https://doi.org/10.1007/s00134-008-1068-x

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Inductive plethysmography to control volume-targeted ventilation for leak compensation

Abstract

Objective

Design and setting

Participants

Intervention

Measurements and results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Objective

Design and setting

Participants

Intervention

Measurements and results

Conclusion

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