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Published in: Intensive Care Medicine 6/2006

01-06-2006 | Clinical Commentary

Avian influenza (H5N1): implications for intensive care

Authors: Pascale C. Gruber, Charles D. Gomersall, Gavin M. Joynt

Published in: Intensive Care Medicine | Issue 6/2006

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Abstract

Background

As influenza A/H5N1 spreads around the globe the risk of an epidemic increases.

Discussion

Review of the cases of influenza A/H5N1 reported to date demonstrates that it causes a severe illness, with a high proportion of patients (63%) requiring advanced organ support. Of these approx. 68% develop multiorgan failure, at least 54% develop acute respiratory distress syndrome, and 90% die. Disease progression is rapid, with a median time from presentation to hospital to requirement for advanced organ support of only 2 days.

Conclusion

The infectious nature, severity and clinical manifestations of the disease and its potential for pandemic spread have considerable implications for intensive care in terms of infection control, patient management, staff morale and intensive care expansion.
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Metadata
Title
Avian influenza (H5N1): implications for intensive care
Authors
Pascale C. Gruber
Charles D. Gomersall
Gavin M. Joynt
Publication date
01-06-2006
Publisher
Springer-Verlag
Published in
Intensive Care Medicine / Issue 6/2006
Print ISSN: 0342-4642
Electronic ISSN: 1432-1238
DOI
https://doi.org/10.1007/s00134-006-0148-z

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