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Published in: Intensive Care Medicine 4/2005

01-04-2005 | Original

Feedback and education improve physician compliance in use of lung-protective mechanical ventilation

Authors: Esther K. Wolthuis, Johanna C. Korevaar, Peter Spronk, Michael A. Kuiper, Misa Dzoljic, Margreeth B. Vroom, Marcus J. Schultz

Published in: Intensive Care Medicine | Issue 4/2005

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Abstract

Objective

Use of lung-protective mechanical ventilation (MV) by applying lower tidal volumes is recommended in patients suffering from acute lung injury (ALI) or acute respiratory distress syndrome (ARDS). Recent data suggest that lung-protective MV may benefit non-ALI/ARDS patients as well. This study analyzed tidal volume settings in three ICUs in The Netherlands to determine the effect of feedback and education concerning use of lung-protective MV.

Design and setting

Observational study in one academic and two nonacademic “closed format” ICUs.

Patients

Intubated mechanically ventilated subjects.

Interventions

Feedback and education concerning lung-protective MV with special attention to the importance of closely adjusting tidal volumes to predicted body weight (PBW).

Results

Tidal volumes declined significantly within 6 months after intervention (from 9.8±2.0 at baseline to 8.1±1.7 ml/kg PBW) as the percentage of undesirable ventilation data points, defined as tidal volumes greater than 8 ml/kg PBW (84% vs. 48%). There were no differences between patients meeting the international definition criteria for ALI/ARDS and those not. Only four patients received tidal volumes less than 6 ml/kg PBW. Lower tidal volumes were still used after 12 months. Tidal volumes in patients on mandatory MV and patients breathing on spontaneous modes were similar.

Conclusions

Feedback and education improve physician compliance in use of lung-protective MV.
Literature
1.
go back to reference Slutsky AS (1999) Lung injury caused by mechanical ventilation. Chest 116:9S-15SCrossRef Slutsky AS (1999) Lung injury caused by mechanical ventilation. Chest 116:9S-15SCrossRef
2.
go back to reference Acute Respiratory Distress Syndrome Network (2000) Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. N Engl J Med 342:1301–1308CrossRefPubMed Acute Respiratory Distress Syndrome Network (2000) Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. N Engl J Med 342:1301–1308CrossRefPubMed
3.
go back to reference Amato MB, Barbas CS, Medeiros DM, Magaldi RB, Schettino GP, Lorenzi-Filho G, Kairalla RA, Deheinzelin D, Munoz C, Oliveira R, Takagaki TY, Carvalho CR (1998) Effect of a protective-ventilation strategy on mortality in the acute respiratory distress syndrome. N Engl J Med 338:347–354CrossRefPubMed Amato MB, Barbas CS, Medeiros DM, Magaldi RB, Schettino GP, Lorenzi-Filho G, Kairalla RA, Deheinzelin D, Munoz C, Oliveira R, Takagaki TY, Carvalho CR (1998) Effect of a protective-ventilation strategy on mortality in the acute respiratory distress syndrome. N Engl J Med 338:347–354CrossRefPubMed
4.
go back to reference Gajic O, Dara SI, Mendez JL, Adesanya AO, Festic E, Caples SM, Rana R, St Sauver JL, Lymp JF, Afessa B, Hubmayr RD (2004) Ventilator-associated lung injury in patients without acute lung injury at the onset of mechanical ventilation. Crit Care Med 32:1817–1824 Gajic O, Dara SI, Mendez JL, Adesanya AO, Festic E, Caples SM, Rana R, St Sauver JL, Lymp JF, Afessa B, Hubmayr RD (2004) Ventilator-associated lung injury in patients without acute lung injury at the onset of mechanical ventilation. Crit Care Med 32:1817–1824
5.
go back to reference Brower RG, Thompson BT, Ancukiewicz M (2004) Clinical trial of mechanical ventilation with traditional versus lower tidal volumes in acute lung injury and acute respiratory distress syndrome: effects on physicians’ practices. Am J Respir Crit Care Med 169:A256 Brower RG, Thompson BT, Ancukiewicz M (2004) Clinical trial of mechanical ventilation with traditional versus lower tidal volumes in acute lung injury and acute respiratory distress syndrome: effects on physicians’ practices. Am J Respir Crit Care Med 169:A256
6.
go back to reference Weinert CR, Gross CR, Marinelli WA (2003) Impact of randomized trial results on acute lung injury ventilator therapy in teaching hospitals. Am J Respir Crit Care Med 167:1304–1309CrossRefPubMed Weinert CR, Gross CR, Marinelli WA (2003) Impact of randomized trial results on acute lung injury ventilator therapy in teaching hospitals. Am J Respir Crit Care Med 167:1304–1309CrossRefPubMed
7.
go back to reference Young MP, Manning HL, Wilson DL, Mette SA, Riker RR, Leiter JC, Liu SK, Bates JT, Parsons PE (2004) Ventilation of patients with acute lung injury and acute respiratory distress syndrome: has new evidence changed clinical practice? Crit Care Med 32:1260–1265 Young MP, Manning HL, Wilson DL, Mette SA, Riker RR, Leiter JC, Liu SK, Bates JT, Parsons PE (2004) Ventilation of patients with acute lung injury and acute respiratory distress syndrome: has new evidence changed clinical practice? Crit Care Med 32:1260–1265
8.
go back to reference Rubenfeld GD, Cooper C, Carter G, Thompson BT, Hudson LD (2004) Barriers to providing lung-protective ventilation to patients with acute lung injury. Crit Care Med 32:1289–1293CrossRefPubMed Rubenfeld GD, Cooper C, Carter G, Thompson BT, Hudson LD (2004) Barriers to providing lung-protective ventilation to patients with acute lung injury. Crit Care Med 32:1289–1293CrossRefPubMed
9.
go back to reference Dedhiya P, Mikkelsen R, Kalhan R, Caughan C, Lanken B (2004) Early clinician recognition of acute lung injury may increase use of lung protective ventilation. Am J Respir Crit Care Med 169:A17 Dedhiya P, Mikkelsen R, Kalhan R, Caughan C, Lanken B (2004) Early clinician recognition of acute lung injury may increase use of lung protective ventilation. Am J Respir Crit Care Med 169:A17
10.
go back to reference Kam EP, Eslick GD, James A, Benson JP (2004) Acute respiratory distress syndrome (ARDS) and low tidal volume ventilation: the debate about weight. Intensive Care Med 30:1502 Kam EP, Eslick GD, James A, Benson JP (2004) Acute respiratory distress syndrome (ARDS) and low tidal volume ventilation: the debate about weight. Intensive Care Med 30:1502
11.
go back to reference Wolthuis E, Spronk P, Kuiper M, Vroom M, Schultz M (2004) Dutch intensivists do not use small tidal volumes (Vt) in mechanical ventilation (MV). Crit Care 8 [Suppl 1]:P26 Wolthuis E, Spronk P, Kuiper M, Vroom M, Schultz M (2004) Dutch intensivists do not use small tidal volumes (Vt) in mechanical ventilation (MV). Crit Care 8 [Suppl 1]:P26
12.
go back to reference Bernard GR, Artigas A, Brigham KL, Carlet J, Falke K, Hudson L, Lamy M, Legall JR, Morris A, Spragg R (1994) The American-European Consensus Conference on ARDS. Definitions, mechanisms, relevant outcomes, and clinical trial coordination. Am J Respir Crit Care Med 149:818–824PubMed Bernard GR, Artigas A, Brigham KL, Carlet J, Falke K, Hudson L, Lamy M, Legall JR, Morris A, Spragg R (1994) The American-European Consensus Conference on ARDS. Definitions, mechanisms, relevant outcomes, and clinical trial coordination. Am J Respir Crit Care Med 149:818–824PubMed
13.
go back to reference Devine B (1974) Gentamicin therapy. Drug Intell Clin Pharm 8:650–655 Devine B (1974) Gentamicin therapy. Drug Intell Clin Pharm 8:650–655
14.
go back to reference Dellinger RP, Carlet JM, Masur H, Gerlach H, Calandra T, Cohen J, Gea-Banacloche J, Keh D, Marshall JC, Parker MM, Ramsay G, Zimmerman JL, Vincent JL, Levy MM (2004) Surviving sepsis campaign guidelines for management of severe sepsis and septic shock. Crit Care Med 32:858–873CrossRefPubMed Dellinger RP, Carlet JM, Masur H, Gerlach H, Calandra T, Cohen J, Gea-Banacloche J, Keh D, Marshall JC, Parker MM, Ramsay G, Zimmerman JL, Vincent JL, Levy MM (2004) Surviving sepsis campaign guidelines for management of severe sepsis and septic shock. Crit Care Med 32:858–873CrossRefPubMed
15.
go back to reference Rubenfeld GD, Caldwell E, Hudson L (2001) Publication of study results does not increase use of lung protective ventilation in patients with acute lung injury. Am J Respir Crit Care Med 163:A295 Rubenfeld GD, Caldwell E, Hudson L (2001) Publication of study results does not increase use of lung protective ventilation in patients with acute lung injury. Am J Respir Crit Care Med 163:A295
16.
go back to reference Tobin MJ, Chadha TS, Jenouri G, Birch SJ, Gazeroglu HB, Sackner MA (1983) Breathing patterns. 1. Normal subjects. Chest 84:202–205 Tobin MJ, Chadha TS, Jenouri G, Birch SJ, Gazeroglu HB, Sackner MA (1983) Breathing patterns. 1. Normal subjects. Chest 84:202–205
17.
go back to reference Hunter J, Rothwell M (2004) New method to evaluate the practice of positive pressure ventilation in intensive care units. Br J Anaesth 92:296–297 Hunter J, Rothwell M (2004) New method to evaluate the practice of positive pressure ventilation in intensive care units. Br J Anaesth 92:296–297
18.
go back to reference Roche RJ, Mackinlay C, McLaughlin A, Panikkar K, Young JD (2003) New method to evaluate the practice of positive pressure ventilation in intensive care units. Br J Anaesth 91:419–420 Roche RJ, Mackinlay C, McLaughlin A, Panikkar K, Young JD (2003) New method to evaluate the practice of positive pressure ventilation in intensive care units. Br J Anaesth 91:419–420
19.
go back to reference Bero LA, Grilli R, Grimshaw JM, Harvey E, Oxman AD, Thomson MA (1998) Getting research findings into practice: closing the gap between research and practice: an overview of systematic reviews of interventions to promote the implementation of research findings. BMJ 317:465–468 Bero LA, Grilli R, Grimshaw JM, Harvey E, Oxman AD, Thomson MA (1998) Getting research findings into practice: closing the gap between research and practice: an overview of systematic reviews of interventions to promote the implementation of research findings. BMJ 317:465–468
20.
go back to reference Cook DJ, Montori VM, McMullin JP, Finfer SR, Rocker GM (2004) Improving patients’ safety locally: changing clinician behaviour. Lancet 363:1224–1230 Cook DJ, Montori VM, McMullin JP, Finfer SR, Rocker GM (2004) Improving patients’ safety locally: changing clinician behaviour. Lancet 363:1224–1230
21.
go back to reference Dreyfuss D, Soler P, Basset G, Saumon G (1988) High inflation pressure pulmonary edema. Respective effects of high airway pressure, high tidal volume, and positive end-expiratory pressure. Am Rev Respir Dis 137:1159–1164PubMed Dreyfuss D, Soler P, Basset G, Saumon G (1988) High inflation pressure pulmonary edema. Respective effects of high airway pressure, high tidal volume, and positive end-expiratory pressure. Am Rev Respir Dis 137:1159–1164PubMed
22.
go back to reference Belperio JA, Keane MP, Burdick MD, Londhe V, Xue YY, Li K, Phillips RJ, Strieter RM (2002) Critical role for CXCR2 and CXCR2 ligands during the pathogenesis of ventilator-induced lung injury. J Clin Invest 110:1703–1716 Belperio JA, Keane MP, Burdick MD, Londhe V, Xue YY, Li K, Phillips RJ, Strieter RM (2002) Critical role for CXCR2 and CXCR2 ligands during the pathogenesis of ventilator-induced lung injury. J Clin Invest 110:1703–1716
23.
go back to reference Wilson MR, Choudhury S, Goddard ME, O’Dea KP, Nicholson AG, Takata M (2003) High tidal volume ventilation upregulates intrapulmonary cytokines in an in vivo mouse model of ventilator-induced lung injury. J Appl Physiol 95:1385–1393PubMed Wilson MR, Choudhury S, Goddard ME, O’Dea KP, Nicholson AG, Takata M (2003) High tidal volume ventilation upregulates intrapulmonary cytokines in an in vivo mouse model of ventilator-induced lung injury. J Appl Physiol 95:1385–1393PubMed
Metadata
Title
Feedback and education improve physician compliance in use of lung-protective mechanical ventilation
Authors
Esther K. Wolthuis
Johanna C. Korevaar
Peter Spronk
Michael A. Kuiper
Misa Dzoljic
Margreeth B. Vroom
Marcus J. Schultz
Publication date
01-04-2005
Publisher
Springer-Verlag
Published in
Intensive Care Medicine / Issue 4/2005
Print ISSN: 0342-4642
Electronic ISSN: 1432-1238
DOI
https://doi.org/10.1007/s00134-005-2581-9

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