Published in:
01-08-2004 | Brief Report
Hyperglycaemia and mortality in critically ill patients
A prospective study
Authors:
Christian Christiansen, Palle Toft, Hans Skriver Jørgensen, Søren Kæseler Andersen, Else Tønnesen
Published in:
Intensive Care Medicine
|
Issue 8/2004
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Abstract
Objective
To describe hyperglycaemia as a possible marker of morbidity and mortality in critically ill medical and surgical patients admitted to a multidisciplinary ICU.
Design
Prospective cohort study.
Setting
A 13-bed non-cardiac multidisciplinary ICU in a university hospital.
Patients and participants
Adult patients consecutively admitted to the ICU in a 6-month period. Patients with fewer than 2 days’ stay in the ICU and patients with known diabetes were excluded.
Measurements and results
At admission a registration form was filled in including demographic data, first and second day APACHE II scores, infections and daily maximum blood glucose level. In surgical patients, high maximum blood glucose level during the stay in ICU was correlated with increased mortality, morbidity and frequency of infection. In medical patients, we found a non-significant trend towards a correlation between hyperglycaemia and morbidity and mortality, respectively.
Conclusions
High blood glucose level during the stay in ICU was a marker of increased morbidity and mortality in critically ill surgical patients. In medical patients the same trend was found, but non-significant. The population of patients in the present study are heterogeneous and the results from surgical critically ill patients should not be generalised to medical patients.