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Intensive Care Medicine
Published in: Intensive Care Medicine 2/2004

01-02-2004 | Original

Breathing pattern variability: a weaning predictor in postoperative patients recovering from systemic inflammatory response syndrome

Authors: Mauo-Ying Bien, Shu-Shya Hseu, Huey-Wen Yien, Benjamin Ing-Tiau Kuo, Yu-Ting Lin, Jia-Horng Wang, Yu Ru Kou

Published in: Intensive Care Medicine | Issue 2/2004

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Abstract

Objective

To investigate whether breathing pattern variability can serve as a potential weaning predictor for postoperative patients recovering from systemic inflammatory response syndrome (SIRS).

Design and setting

A prospective measurement of retrospectively analyzed breathing pattern variability in a surgical intensive care unit.

Patients

Seventy-eight mechanically ventilated SIRS patients who had undergone abdominal surgery were included when they were ready for weaning. They were divided into success (n=57) and failure (n=21) groups based upon their weaning outcome.

Measurements and results

Before weaning, tidal volume, total breath duration, inspiratory time, expiratory time, and peak inspiratory flow were continuously monitored for 30 min, while patients received 5 cmH2O pressure support weaning trial. After the patients successfully completed the trial, they were extubated. Successful weaning was defined as patients free from the ventilator for over 48 h, whereas a weaning failure was considered as reinstitution of mechanical ventilation within 48 h of extubation. The coefficient of variation and two values of standard deviation (SD1 and SD2; indicators of the dispersion of data points in the plot) obtained from the Poincaré plot of five respiratory parameters in the failure group were significantly lower than those in the success group. The area under the receiver operating characteristic curve of these variability indices was within the range of 0.73–0.80, indicating the accuracy of prediction.

Conclusions

Small breathing pattern variability is associated with a high incidence of weaning failure in postoperative patients recovering from SIRS, and this variability may potentially serve as a weaning predictor.
Appendix
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Metadata
Title
Breathing pattern variability: a weaning predictor in postoperative patients recovering from systemic inflammatory response syndrome
Authors
Mauo-Ying Bien
Shu-Shya Hseu
Huey-Wen Yien
Benjamin Ing-Tiau Kuo
Yu-Ting Lin
Jia-Horng Wang
Yu Ru Kou
Publication date
01-02-2004
Publisher
Springer Berlin Heidelberg
Published in
Intensive Care Medicine / Issue 2/2004
Print ISSN: 0342-4642
Electronic ISSN: 1432-1238
DOI
https://doi.org/10.1007/s00134-003-2073-8

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