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Published in: Social Psychiatry and Psychiatric Epidemiology 3/2013

01-03-2013 | Original Paper

Premenstrual dysphoric disorder as a correlate of suicidal ideation, plans, and attempts among a nationally representative sample

Authors: Corey E. Pilver, Daniel J. Libby, Rani A. Hoff

Published in: Social Psychiatry and Psychiatric Epidemiology | Issue 3/2013

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Abstract

Purpose

Suicide is a major public health concern and a leading cause of death in the United States. Psychopathology is an established risk factor for non-fatal suicidal behavior; however, it is unclear whether Premenstrual Dysphoric Disorder (PMDD), a psychiatric disorder specific to women, is correlated with these outcomes. The objective of this study was to determine if PMDD status was associated with suicidal ideation, plans, and attempts, independent of socio-demographic factors and psychiatric comorbidity.

Methods

We conducted a secondary data analysis of 3,965 American women aged 18–40 who participated in the Collaborative Psychiatric Epidemiology Survey. Descriptive statistics and forward stepwise logistic regression modeling were performed using SUDAAN software.

Results

The prevalence of non-fatal suicidal behaviors increased in a graded fashion according to PMDD status. Although the control for demographic characteristics and psychiatric comorbidity greatly attenuated the unadjusted association between PMDD and suicidal behaviors, women with PMDD remained significantly more likely than women with no premenstrual symptoms to report suicidal ideation (OR 2.22; 95 % CI 1.40–3.53), plans (OR 2.27; 95 % CI 1.20–4.28), and attempts (OR 2.10; 95 % CI 1.08–4.08). Only the likelihood of suicidal ideation was significantly elevated among women with moderate/severe premenstrual syndrome (PMS; OR 1.49; 95 % CI 1.17–1.88), compared to women with no premenstrual symptoms.

Conclusions

PMDD was strongly and independently associated with non-fatal suicidal behaviors among a nationally representative sample. These findings suggest that clinicians treating women with PMDD should assess and be vigilant for signs of non-fatal suicidal behavior, and that clinicians should evaluate and treat the premenstrual symptoms of women who express these behaviors.
Literature
1.
go back to reference Centers for Disease Control and Prevention NCfIPaC. Understanding suicide fact sheet. 2010 Centers for Disease Control and Prevention NCfIPaC. Understanding suicide fact sheet. 2010
2.
go back to reference Nock MK, Hwang I, Sampson NA, Kessler RC (2010) Mental disorders, comorbidity and suicidal behavior: results from the National Comorbidity Survey Replication. Mol Psychiatry 15(8):868–876PubMedCrossRef Nock MK, Hwang I, Sampson NA, Kessler RC (2010) Mental disorders, comorbidity and suicidal behavior: results from the National Comorbidity Survey Replication. Mol Psychiatry 15(8):868–876PubMedCrossRef
3.
go back to reference McLean J, Maxwell M, Platt S, Harris F, and Jepson R. (2008) Risk and protective factors for suicide and suicidal behaviour: a literature review. Edinborough McLean J, Maxwell M, Platt S, Harris F, and Jepson R. (2008) Risk and protective factors for suicide and suicidal behaviour: a literature review. Edinborough
4.
go back to reference American Psychiatric Association (1994) Diagnostic and statistical manual of mental disorders, 4th edn. American Psychiatric Press, Washington DC, p 886 American Psychiatric Association (1994) Diagnostic and statistical manual of mental disorders, 4th edn. American Psychiatric Press, Washington DC, p 886
5.
go back to reference Halbreich U, Borenstein J, Pearlstein T, Kahn L (2003) The prevalence, impairment, impact, and burden of premenstrual dysphoric disorder [PMS/PMDD]. Psychoneuroendocrinology 28(Suppl 3):1–23 Halbreich U, Borenstein J, Pearlstein T, Kahn L (2003) The prevalence, impairment, impact, and burden of premenstrual dysphoric disorder [PMS/PMDD]. Psychoneuroendocrinology 28(Suppl 3):1–23
6.
go back to reference Clayton A (2008) Symptoms related to the menstrual cycle: diagnosis, prevalence, and treatment. J Psychiatr Pract 14(1):13–21PubMedCrossRef Clayton A (2008) Symptoms related to the menstrual cycle: diagnosis, prevalence, and treatment. J Psychiatr Pract 14(1):13–21PubMedCrossRef
7.
go back to reference Yonkers KA, Pearlstein T, Rosenheck RA (2003) Premenstrual disorders: bridging research and clinical reality. Arch Womens Ment Health 6(4):287–292PubMedCrossRef Yonkers KA, Pearlstein T, Rosenheck RA (2003) Premenstrual disorders: bridging research and clinical reality. Arch Womens Ment Health 6(4):287–292PubMedCrossRef
8.
go back to reference Baca-Garcia E, Diaz-Sastre C, Ceverino A, García Resa E, Oquendo MA, Saiz-Ruiz J et al (2004) Premenstrual symptoms and luteal suicide attempts. Eur Arch Psychiatry Clin Neurosci 254(5):326–329PubMedCrossRef Baca-Garcia E, Diaz-Sastre C, Ceverino A, García Resa E, Oquendo MA, Saiz-Ruiz J et al (2004) Premenstrual symptoms and luteal suicide attempts. Eur Arch Psychiatry Clin Neurosci 254(5):326–329PubMedCrossRef
9.
go back to reference Lieb R, Isensee B, von Sydow K, Wittchen HU (2000) The Early Developmental Stages of Psychopathology Study [EDSP]: a methodological update. Eur Addict Res 6(4):170–182PubMedCrossRef Lieb R, Isensee B, von Sydow K, Wittchen HU (2000) The Early Developmental Stages of Psychopathology Study [EDSP]: a methodological update. Eur Addict Res 6(4):170–182PubMedCrossRef
10.
go back to reference Wittchen H, Becker E, Lieb R, Krause P (2002) Prevalence, incidence and stability of premenstrual dysphoric disorder in the community. Psychol Med 32(1):119–132PubMedCrossRef Wittchen H, Becker E, Lieb R, Krause P (2002) Prevalence, incidence and stability of premenstrual dysphoric disorder in the community. Psychol Med 32(1):119–132PubMedCrossRef
11.
go back to reference Kessler R, Merikangas K (2004) The National Comorbidity Survey Replication [NCS-R]: background and aims. Int J Methods Psychiatr Res 13(2):60–68PubMedCrossRef Kessler R, Merikangas K (2004) The National Comorbidity Survey Replication [NCS-R]: background and aims. Int J Methods Psychiatr Res 13(2):60–68PubMedCrossRef
12.
go back to reference Alegria M, Takeuchi D, Canino G, Duan N, Shrout P, Meng X et al (2004) Considering context, place and culture: the National Latino and Asian American study. Int J Methods Psychiatr Res 13(4):208–220PubMedCrossRef Alegria M, Takeuchi D, Canino G, Duan N, Shrout P, Meng X et al (2004) Considering context, place and culture: the National Latino and Asian American study. Int J Methods Psychiatr Res 13(4):208–220PubMedCrossRef
13.
go back to reference Jackson J, Torres M, Caldwell C, Neighbors H, Nesse R, Taylor R et al (2004) The National Survey of American Life: a study of racial, ethnic and cultural influences on mental disorders and mental health. Int J Methods Psychiatr Res 13(4):196–207PubMedCrossRef Jackson J, Torres M, Caldwell C, Neighbors H, Nesse R, Taylor R et al (2004) The National Survey of American Life: a study of racial, ethnic and cultural influences on mental disorders and mental health. Int J Methods Psychiatr Res 13(4):196–207PubMedCrossRef
14.
go back to reference Heeringa S, Wagner J, Torres M, Duan N, Adams T, Berglund P (2004) Sample designs and sampling methods for the Collaborative Psychiatric Epidemiology Studies [CPES]. Int J Methods Psychiatr Res 13(4):221–240PubMedCrossRef Heeringa S, Wagner J, Torres M, Duan N, Adams T, Berglund P (2004) Sample designs and sampling methods for the Collaborative Psychiatric Epidemiology Studies [CPES]. Int J Methods Psychiatr Res 13(4):221–240PubMedCrossRef
15.
go back to reference Pennell B, Bowers A, Carr D, Chardoul S, Cheung G, Dinkelmann K et al (2004) The development and implementation of the National Comorbidity Survey Replication, the National Survey of American Life, and the National Latino and Asian American Survey. Int J Methods Psychiatr Res 13(4):241–269PubMedCrossRef Pennell B, Bowers A, Carr D, Chardoul S, Cheung G, Dinkelmann K et al (2004) The development and implementation of the National Comorbidity Survey Replication, the National Survey of American Life, and the National Latino and Asian American Survey. Int J Methods Psychiatr Res 13(4):241–269PubMedCrossRef
16.
go back to reference Kessler R, Abelson J, Demler O, Escobar J, Gibbon M, Guyer M et al (2004) Clinical calibration of DSM-IV diagnoses in the World Mental Health [WMH] version of the World Health Organization [WHO] Composite International Diagnostic Interview [WMHCIDI]. Int J Methods Psychiatr Res 13(2):122–139PubMedCrossRef Kessler R, Abelson J, Demler O, Escobar J, Gibbon M, Guyer M et al (2004) Clinical calibration of DSM-IV diagnoses in the World Mental Health [WMH] version of the World Health Organization [WHO] Composite International Diagnostic Interview [WMHCIDI]. Int J Methods Psychiatr Res 13(2):122–139PubMedCrossRef
17.
go back to reference Deuster P, Adera T, South-Paul J (1999) Biological, social, and behavioral factors associated with premenstrual syndrome. Arch Fam Med 8(2):122–128PubMedCrossRef Deuster P, Adera T, South-Paul J (1999) Biological, social, and behavioral factors associated with premenstrual syndrome. Arch Fam Med 8(2):122–128PubMedCrossRef
18.
go back to reference Kessler RC, Borges G, Walters EE (1999) Prevalence of and risk factors for lifetime suicide attempts in the National Comorbidity Survey. Arch Gen Psychiatry 56(7):617–626PubMedCrossRef Kessler RC, Borges G, Walters EE (1999) Prevalence of and risk factors for lifetime suicide attempts in the National Comorbidity Survey. Arch Gen Psychiatry 56(7):617–626PubMedCrossRef
19.
go back to reference Crowne DP, Marlowe D (1960) A new scale of social desirability independent of psychopathology. J Consult Psychol 24(4):349–354PubMedCrossRef Crowne DP, Marlowe D (1960) A new scale of social desirability independent of psychopathology. J Consult Psychol 24(4):349–354PubMedCrossRef
20.
go back to reference Aschengrau A, Seage GRI (2008) Essentials of epidemiology in public health, 2nd edn. Jones and Barlett Publishers, Sudbury, MA Aschengrau A, Seage GRI (2008) Essentials of epidemiology in public health, 2nd edn. Jones and Barlett Publishers, Sudbury, MA
22.
go back to reference Szklo M, Nieto FJ (2004) Epidemiology beyond the basics. Jones and Barlett Publishers, Boston Szklo M, Nieto FJ (2004) Epidemiology beyond the basics. Jones and Barlett Publishers, Boston
23.
go back to reference Grant BF. (2004-2005) Wave 2 National Epidemiologic Survey of Alcohol and Related Conditions [NESARC] Grant BF. (2004-2005) Wave 2 National Epidemiologic Survey of Alcohol and Related Conditions [NESARC]
24.
go back to reference Landén M, Eriksson E (2003) How does premenstrual dysphoric disorder relate to depression and anxiety disorders? Depress Anxiety 17(3):122–129PubMedCrossRef Landén M, Eriksson E (2003) How does premenstrual dysphoric disorder relate to depression and anxiety disorders? Depress Anxiety 17(3):122–129PubMedCrossRef
25.
go back to reference Endicott J, Amsterdam J, Eriksson E, Frank E, Freeman E, Hirschfeld R et al (1999) Is premenstrual dysphoric disorder a distinct clinical entity? J Womens Health Gend Based Med 8(5):663–679PubMedCrossRef Endicott J, Amsterdam J, Eriksson E, Frank E, Freeman E, Hirschfeld R et al (1999) Is premenstrual dysphoric disorder a distinct clinical entity? J Womens Health Gend Based Med 8(5):663–679PubMedCrossRef
26.
go back to reference Vigod SN, Frey BN, Soares CN, Steiner M (2010) Approach to premenstrual dysphoria for the mental health practitioner. Psychiatr Clin North Am 33(2):257–272PubMedCrossRef Vigod SN, Frey BN, Soares CN, Steiner M (2010) Approach to premenstrual dysphoria for the mental health practitioner. Psychiatr Clin North Am 33(2):257–272PubMedCrossRef
27.
go back to reference Joiner TE Jr, Brown JS, Wingate LR (2005) The psychology and neurobiology of suicidal behavior. Annu Rev Psychol 56(1):287PubMedCrossRef Joiner TE Jr, Brown JS, Wingate LR (2005) The psychology and neurobiology of suicidal behavior. Annu Rev Psychol 56(1):287PubMedCrossRef
28.
go back to reference Steiner M, Pearlstein T (2000) Premenstrual dysphoria and the serotonin system: pathophysiology and treatment. J Clin Psychiatr 61(Suppl 12):17–21 Steiner M, Pearlstein T (2000) Premenstrual dysphoria and the serotonin system: pathophysiology and treatment. J Clin Psychiatr 61(Suppl 12):17–21
30.
go back to reference Taylor DL, Mathew RJ, Ho BT, Weinman ML (1984) Serotonin levels and platelet uptake during premenstrual tension. Neuropsychobiology 12(1):16–18PubMedCrossRef Taylor DL, Mathew RJ, Ho BT, Weinman ML (1984) Serotonin levels and platelet uptake during premenstrual tension. Neuropsychobiology 12(1):16–18PubMedCrossRef
31.
go back to reference Rapkin AJ, Edelmuth E, Chang LC, Reading AE, McGuire MT, Su TP (1987) Whole blood serotonin in premenstrual syndrome. Obstet Gynecol 70(4):533–537PubMed Rapkin AJ, Edelmuth E, Chang LC, Reading AE, McGuire MT, Su TP (1987) Whole blood serotonin in premenstrual syndrome. Obstet Gynecol 70(4):533–537PubMed
32.
go back to reference Hartlage SA, Arduino KE, Gehlert S (2001) Premenstrual dysphoric disorder and risk for major depressive disorder: a preliminary study. J Clin Psychol 57(12):1571–1578PubMedCrossRef Hartlage SA, Arduino KE, Gehlert S (2001) Premenstrual dysphoric disorder and risk for major depressive disorder: a preliminary study. J Clin Psychol 57(12):1571–1578PubMedCrossRef
33.
go back to reference Perkonigg A, Yonkers K, Pfister H, Lieb R, Wittchen H (2004) Risk factors for premenstrual dysphoric disorder in a community sample of young women: the role of traumatic events and posttraumatic stress disorder. J Clin Psychiatry 65(10):1314–1322PubMedCrossRef Perkonigg A, Yonkers K, Pfister H, Lieb R, Wittchen H (2004) Risk factors for premenstrual dysphoric disorder in a community sample of young women: the role of traumatic events and posttraumatic stress disorder. J Clin Psychiatry 65(10):1314–1322PubMedCrossRef
34.
go back to reference Pearlstein T, Steiner M (2008) Premenstrual dysphoric disorder: burden of illness and treatment update. J Psychiatry Neurosci 33(4):291–301PubMed Pearlstein T, Steiner M (2008) Premenstrual dysphoric disorder: burden of illness and treatment update. J Psychiatry Neurosci 33(4):291–301PubMed
Metadata
Title
Premenstrual dysphoric disorder as a correlate of suicidal ideation, plans, and attempts among a nationally representative sample
Authors
Corey E. Pilver
Daniel J. Libby
Rani A. Hoff
Publication date
01-03-2013
Publisher
Springer-Verlag
Published in
Social Psychiatry and Psychiatric Epidemiology / Issue 3/2013
Print ISSN: 0933-7954
Electronic ISSN: 1433-9285
DOI
https://doi.org/10.1007/s00127-012-0548-z

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