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Published in: Social Psychiatry and Psychiatric Epidemiology 1/2010

01-01-2010 | Original Paper

Pain associated with specific anxiety and depressive disorders in a nationally representative population sample

Authors: Katja Beesdo, Frank Jacobi, Jürgen Hoyer, Nancy C. P. Low, Michael Höfler, Hans-Ulrich Wittchen

Published in: Social Psychiatry and Psychiatric Epidemiology | Issue 1/2010

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Abstract

Objective

To examine in a nationally representative sample (a) the differential association of specific anxiety and depressive disorders defined according to DSM-IV with pain disorder (PD) and pain symptoms, and (b) whether pain-associated anxiety and depressive disorders and their comorbidity have different implications in terms of impairment, disability, health care utilization, and substance use.

Method

A nationally representative community study was conducted in Germany. Symptoms, syndromes and diagnoses of mental disorders, and pain were assessed in N = 4,181 participants aged 18–65 years using the DSM-IV/M-CIDI.

Results

Logistic regressions revealed that pain is associated with both specific anxiety and depressive disorders, with increasing significant odds ratios (OR) for medically explained pain symptoms (EPS; OR range: 1.9–2.0), to unexplained pain symptoms (UPS; OR range: 2.4–7.3), to PD (OR range: 3.3–14.8). PD and UPS persistently showed associations after adjusting for comorbid other anxiety and depressive disorders and physical illnesses. All types of pain, particularly PD/UPS, are associated with decreased quality of life, greater impairment in role functioning, disability, health care utilization, and substance use. Depressive disorders, even more so anxiety disorders and their comorbidity account for a substantial proportion of variance in these functional correlates.

Conclusions

Pain is strongly associated with specific anxiety and depressive disorders. In light of the individual and societal burden due to pain, and the demonstrated role of comorbid anxiety or/and depression, our results call for further investigation of the underlying mechanisms for this association as well as targeted treatments for these comorbidities.
Footnotes
1
For ratios >1: {0 − [1 − (adjusted ratio − 1)/(unadjusted ratio − 1)] × 100},
For ratios <1: {1 − [adjusted ratio − 1)/(unadjusted ratio − 1)] × 100}.
 
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Metadata
Title
Pain associated with specific anxiety and depressive disorders in a nationally representative population sample
Authors
Katja Beesdo
Frank Jacobi
Jürgen Hoyer
Nancy C. P. Low
Michael Höfler
Hans-Ulrich Wittchen
Publication date
01-01-2010
Publisher
D. Steinkopff-Verlag
Published in
Social Psychiatry and Psychiatric Epidemiology / Issue 1/2010
Print ISSN: 0933-7954
Electronic ISSN: 1433-9285
DOI
https://doi.org/10.1007/s00127-009-0045-1

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