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01-09-2013 | Original article

Clinical and technical characteristics of intraoperative radiotherapy

Analysis of the ISIORT-Europe database

Authors: M. Krengli, MD, F.A. Calvo, F. Sedlmayer, C.V. Sole, G. Fastner, M. Alessandro, S. Maluta, R. Corvò, E. Sperk, M. Litoborski, C. Pisani, C. Fillini, F. Fusconi, M.F. Osti, L. Tomio, H. Marsiglia, A. Ciabattoni, W. Polkowski, A. Di Grazia, A. Gava, A. Kuten, C. Iotti, C. Gonzalez, M. Sallabanda, J.-B. Dubois, G. Catalano, V. Valentini

Published in: Strahlentherapie und Onkologie | Issue 9/2013

Abstract

Background

A joint analysis of clinical data from centres within the European section of the International Society of Intraoperative Radiation Therapy (ISIORT-Europe) was undertaken in order to define the range of intraoperative radiotherapy (IORT) techniques and indications encompassed by its member institutions.

Materials and methods

In 2007, the ISIORT-Europe centres were invited to record demographic, clinical and technical data relating to their IORT procedures in a joint online database. Retrospective data entry was possible.

Results

The survey encompassed 21 centres and data from 3754 IORT procedures performed between 1992 and 2011. The average annual number of patients treated per institution was 42, with three centres treating more than 100 patients per year. The most frequent tumour was breast cancer with 2395 cases (63.8 %), followed by rectal cancer (598 cases, 15.9 %), sarcoma (221 cases, 5.9 %), prostate cancer (108 cases, 2.9 %) and pancreatic cancer (80 cases, 2.1 %). Clinical details and IORT technical data from these five tumour types are reported.

Conclusion

This is the first report on a large cohort of patients treated with IORT in Europe. It gives a picture of patient selection methods and treatment modalities, with emphasis on the main tumour types that are typically treated by this technique and may benefit from it.

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Title: Clinical and technical characteristics of intraoperative radiotherapy
Analysis of the ISIORT-Europe database
Authors: M. Krengli, MD
F.A. Calvo
F. Sedlmayer
C.V. Sole
G. Fastner
M. Alessandro
S. Maluta
R. Corvò
E. Sperk
M. Litoborski
C. Pisani
C. Fillini
F. Fusconi
M.F. Osti
L. Tomio
H. Marsiglia
A. Ciabattoni
W. Polkowski
A. Di Grazia
A. Gava
A. Kuten
C. Iotti
C. Gonzalez
M. Sallabanda
J.-B. Dubois
G. Catalano
V. Valentini
Publication date: 01-09-2013
Publisher: Springer Berlin Heidelberg
Published in: Strahlentherapie und Onkologie / Issue 9/2013
Print ISSN: 0179-7158
Electronic ISSN: 1439-099X
DOI: https://doi.org/10.1007/s00066-013-0395-1

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Clinical and technical characteristics of intraoperative radiotherapy

Analysis of the ISIORT-Europe database

Abstract

Background

Materials and methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Materials and methods

Results

Conclusion

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