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01-03-2015 | Clinical Case

Freiburg Neuropathology Case Conference: A Patient with Chronic Nasal Obstruction

Authors: C.A. Taschner, V.A. Frey, C. Offergeld, H. Urbach, C.J. Maurer, G. Kayser

Published in: Clinical Neuroradiology | Issue 1/2015

Excerpt

A 57-year-old man presented with nasal obstruction present for a period of 2 years. Nasal obstruction seemed more pronounced in the evening. He reported to have a sore throat, mainly in the morning. There was no evidence of nasal bleeding or headache. He reported to already have visited an ear-nose-throat (ENT) specialist, who had made a prescription of a nasal ointment that did not have any effect on his symptoms. Otorhinolaryngologic examination revealed a deviation of the nasal septum to the right. Endoscopic examination of the nose showed a brownish tumor of the nasopharynx with an approximate size of 3 cm. However, while listening to the patient, it became obvious that he had a nasal speech. Olfactometric testing demonstrated bilateral dysosmia; rhinomanometry showed a pronounced bilateral nasal obstruction. Pure tone audiometry revealed normal hearing results, while tympanometric testing demonstrated negative pressure on both sides. …

King AD, Lei KI, Richards PS, Ahuja AT. Non-Hodgkin’s lymphoma of the nasopharynx: CT and MR imaging. Clin Radiol. 2003;58:621–5.CrossRefPubMed

Abdel Khalek Abdel Razek A, King A. MRI and CT of nasopharyngeal carcinoma. AJR Am J Roentgenol. 2012;198:11–8.CrossRefPubMed

Ching AS, Khoo JB, Chong VF. CT and MR imaging of solitary extramedullary plasmacytoma of the nasal tract. AJNR Am J Neuroradiol. 2002;23:1632–6.PubMed

Chang YL, Chen PY, Hung SH. Extramedullary plasmacytoma of the nasopharynx: a case report and review of the literature. Oncol Lett. 2014;7:458–60.PubMedCentralPubMed

Berrettini S, Fortunato S, De Vito A, Bruschini L. A rare case of nasopharyngeal pleomorphic adenoma. Case Rep Otolaryngol. 2013;2013:712873.PubMedCentralPubMed

Schick B, Kahle G. Radiological findings in angiofibroma. Acta Radiol. 2000;41:585–93.CrossRefPubMed

Korolkowa O, Osuch-Wójcikiewicz E, Deptała A, Suleiman W. Extramedullary plasmacytoma of the head and neck. Otolaryngol Pol. 2004;58:1009–12.PubMed

González JB, González FB, Muñoz Herrera A, Nieto García A, Antúñez Plaza P, Pérez Plasencia D, del Cañizo Alvarez A. Extramedullary plasmacytoma of the head and neck. Report of 3 clinical cases. An Otorrinolaringol Ibero Am. 2003;30:501–11.PubMed

Fu YS, Perzin KH. Nonepithelial tumors of the nasal cavity, paranasal sinuses, and nasopharynx. A clinicopathologic study VI. Fibrous tissue tumors (fibroma, fibromatosis, fibrosarcoma). Cancer. 1976;37:2912–28.CrossRefPubMed

10.

Knowling MA, Harwood AR, Bergsagel DE. Comparison of extramedullary plasmacytomas with solitary and multiple plasma cell tumors of bone. J Clin Oncol. 1983;1:255–62.PubMed

11.

Galieni P, Cavo M, Pulsoni A, Avvisati G, Bigazzi C, Neri S, Caliceti U, Benni M, Ronconi S, Lauria F. Clinical outcome of extramedullary plasmacytoma. Haematologica. 2000;85:47–51.PubMed

12.

Straetmans J, Stokroos R. Extramedullary plasmacytomas in the head and neck region. Eur Arch Otorhinolaryngol. 2008;265:1417–23.CrossRefPubMed

13.

Miller FR, Lavertu P, Wanamaker JR, Bonafede J, Wood BG. Plasmacytomas of the head and neck. Otolaryngol Head Neck Surg. 1998;119:614–8.CrossRefPubMed

14.

Nofsinger YC, Mirza N, Rowan PT, Lanza D, Weinstein G. Head and neck manifestations of plasma cell neoplasms. Laryngoscope. 1997;107:741–6.CrossRefPubMed

15.

Soutar R, Lucraft H, Jackson G, Reece A, Bird J, Low E, Samson D; Guidelines Working Group of the UK Myeloma Forum; British Committee for Standards in Haematology; British Society for Haematology. Guidelines on the diagnosis and management of solitary plasmacytoma of bone and solitary extramedullary plasmacytoma. Br J Haematol. 2004;124:717–26.CrossRefPubMed

16.

Sasaki R, Yasuda K, Abe E, Uchida N, Kawashima M, Uno T, Fujiwara M, Shioyama Y, Kagami Y, Shibamoto Y, Nakata K, Takada Y, Kawabe T, Uehara K, Nibu K, Yamada S. Multi-institutional analysis of solitary extramedullary plasmacytoma of the head and neck treated with curative radiotherapy. Int J Radiat Oncol Biol Phys. 2012;82:626–34.CrossRefPubMed

17.

Sasaki S, Hashimoto K, Nakatsuka S, Hasegawa M, Nakano T, Nagata S, Kanakura Y, Hayashi N. Plasmablastic extramedullary plasmacytoma associated with Epstein-Barr virus arising in an immunocompetent patient with multiple myeloma. Intern Med. 2011;50:2615–20.CrossRefPubMed

18.

Susnerwala SS, Shanks JH, Banerjee SS, Scarffe JH, Farrington WT, Slevin NJ. Extramedullary plasmacytoma of the head and neck region: clinicopathological correlation in 25 cases. Br J Cancer. 1997;75:921–7.CrossRefPubMedCentralPubMed

Title: Freiburg Neuropathology Case Conference: A Patient with Chronic Nasal Obstruction
Authors: C.A. Taschner
V.A. Frey
C. Offergeld
H. Urbach
C.J. Maurer
G. Kayser
Publication date: 01-03-2015
Publisher: Springer Berlin Heidelberg
Published in: Clinical Neuroradiology / Issue 1/2015
Print ISSN: 1869-1439
Electronic ISSN: 1869-1447
DOI: https://doi.org/10.1007/s00062-015-0373-3

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Freiburg Neuropathology Case Conference: A Patient with Chronic Nasal Obstruction

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