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01-04-2011 | Correspondence

Structural and Functional Involvement of Pituitary Gland in Wegener’s Granulomatosis

Authors: N. B. Barlas, FRCR, Hamdy H. Hassan, FRCR, F. B. Al Badr, MD, A. Bilal, MBBS

Published in: Clinical Neuroradiology | Issue 1/2011

Abstract

A case of involvement of the pituitary gland in Wegener’s granulomatosis in a patient with diabetes inspidus and hyperprolactinemia is presented. Initial magnetic resonance imaging (MRI) revealed loss of normal high signal in the posterior pituitary on T1-weighted images (T1WI) while the anterior pituitary was enlarged showing a central low signal intensity area on T1WI and high signal intensity on T2WI. Repeated MRI after treatment showed almost complete radiological resolution of these abnormalities along with clinical improvement.

Leavitt RY, Fauci AS. Pulmonary vasculitis. Am Rev Respir Dis. 1986;134:149–66.PubMed

Nishino H, Rubino FA, DeRemee RA, Swanson JW, Parisi JE. Neurological involvement in Wegener’s granulomatosis: an analysis of 324 consecutive patients at the Mayo Clinic. Ann Neurol. 1993;33:4–9.PubMedCrossRef

Hoffman GS, Kerr GS, Leavitt RY, Hallahan CW, Lebovics RS, Travis WD, Rottem M, Fauci AS. Wegener granulomatosis: an analysis of 158 patients. Ann Intern Med. 1992;116:488–98.PubMed

Czarnecki EJ, Spickler EM. MR demonstration of Wegener granulomatosis of the infundibulum, a cause of diabetes insipidus. AJNR Am J Neuroradiol. 1995;16 Suppl 4:968–70.PubMed

Fauci AS, Haynes BF, Katz P, Wolff SM. Wegener’s granulomatosis: prospective clinical and therapeutic experience with 85 patients for 21 years. Ann Intern Med. 1983;98:76–85.PubMed

Miesen WM, Janssens EN, van Bommel EF. Diabetes insipidus as the presenting symptom of Wegener’s granulomatosis. Nephrol Dial Transplant. 1999;14:426–9.PubMedCrossRef

Dwyer J, Janzen VD. Wegener’s granulomatosis with otological and nervous system involvement. J Otolaryngol. 1981;10:476–80.PubMed

Goyal M, Kucharczyk W, Keystone E. Granulomatous hypophysitis due to Wegener’s granulomatosis. AJNR Am J Neuroradiol. 2000;21:1466–9.PubMed

Katzman GL, Langford CA, Sneller MC, Koby M, Patronas NJ. Pituitary involvement by Wegener’s granulomatosis: a report of two cases. AJNR Am J Neuroradiol. 1999;20:519–23.PubMed

10.

Unlühizarci K, Bayram F, Colak R, Oztürk F, Selçuklu A, Durak AC, Keleştimur F. Distinct radiological and clinical appearance of lymphocytic hypophysitis. J Clin Endocrinol Metab. 2001;5:1861–4.CrossRef

Title: Structural and Functional Involvement of Pituitary Gland in Wegener’s Granulomatosis
Authors: N. B. Barlas, FRCR
Hamdy H. Hassan, FRCR
F. B. Al Badr, MD
A. Bilal, MBBS
Publication date: 01-04-2011
Publisher: Springer-Verlag
Published in: Clinical Neuroradiology / Issue 1/2011
Print ISSN: 1869-1439
Electronic ISSN: 1869-1447
DOI: https://doi.org/10.1007/s00062-010-0037-2

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Structural and Functional Involvement of Pituitary Gland in Wegener’s Granulomatosis

Abstract

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Abstract

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