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BMC Musculoskeletal Disorders

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Open Access 01-12-2024 | Refracture | Research

Effect of sarcopenia on refractures of adjacent vertebra after percutaneous kyphoplasty

Authors: Chengnan Jing, Huazheng Wang, Peng Liu, Shaofeng Yang, Linlin Zhang, Peng Yang, Minfeng Gan

Published in: BMC Musculoskeletal Disorders | Issue 1/2024

Abstract

Purpose

To explore the effect of sarcopenia on recurrent fractures of adjacent vertebra after percutaneous kyphoplasty (PKP).

Methods

A total of 376 osteoporotic vertebral compression fractures (OVCFs) patients over 55 years old who were admitted to the Hospital from August 2020 to January 2021 were selected. Among them, 38 patients with recurrent fractures in adjacent vertebra after PKP were selected as the refracture group (RG), and the remaining 338 patients were selected as the non-refracture group (NRG). The age, gender, grip strength, body mass index (BMI), bone mineral density (BMD), visual analogue scale (VAS) of pain before and one month after surgery, Oswestry disability index (ODI) before and one month after surgery and the occurrence of sarcopenia were compared between the two groups. Logistic regression analysis was used to evaluate the effect of related risk factors on refracture after vertebral PKP.

Results

The results of t-test and Chi-square test showed that there were no obvious differences in gender, BMI, preoperative VAS score (t=-0.996, P = 0.320) and ODI (t=-0.424, P = 0.671), one month postoperative VAS score (t=-0.934, P = 0.355) and ODI score (t=-0.461, P = 0.645). while the age and grip strength showed significant differences between the two groups. Logistic regression analysis showed that BMI and gender had no significant effect on refracture after PKP, while sarcopenia and advanced age were independent risk factors for refracture after PKP. Also, increased BMD was a protective factor for refracture after PKP.

Conclusion

Sarcopenia is an independent risk factor for recurrent fractures after PKP in OVCF patients. The screening and diagnosis of sarcopenia should be strengthened. At the same time, anti-sarcopenia treatment should be actively performed after surgery.

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Title: Effect of sarcopenia on refractures of adjacent vertebra after percutaneous kyphoplasty
Authors: Chengnan Jing
Huazheng Wang
Peng Liu
Shaofeng Yang
Linlin Zhang
Peng Yang
Minfeng Gan
Publication date: 01-12-2024
Publisher: BioMed Central
Keywords: Refracture
Sarcopenia
Published in: BMC Musculoskeletal Disorders / Issue 1/2024
Electronic ISSN: 1471-2474
DOI: https://doi.org/10.1186/s12891-024-07295-3

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Effect of sarcopenia on refractures of adjacent vertebra after percutaneous kyphoplasty

Abstract

Purpose

Methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusion

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