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BMC Surgery
Published in: BMC Surgery 1/2023

Open Access 01-12-2023 | Uvulopalatopharyngoplasty | Research

The relationship of tongue fat content and efficacy of uvulopalatopharyngoplasty in Chinese patients with obstructive sleep apnea

Authors: Bingjie Zhao, Zine Cao, Yushan Xie, Yewen Shi, Yitong Zhang, Shiyu Liu, Xi Chen, Lina Ma, Xiaoxin Niu, Yonglong Su, Yani Feng, Chunfeng Lian, Xiaoyong Ren, Haiqin Liu

Published in: BMC Surgery | Issue 1/2023

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Abstract

Background

To investigate the relationship between tongue fat content and severity of obstructive sleep apnea (OSA) and its effects on the efficacy of uvulopalatopharyngoplasty (UPPP) in the Chinese group.

Method

Fifty-two participants concluded to this study were diagnosed as OSA by performing polysomnography (PSG) then they were divided into moderate group and severe group according to apnea hypopnea index (AHI). All of them were also collected a series of data including age, BMI, height, weight, neck circumference, abdominal circumference, magnetic resonance imaging (MRI) of upper airway and the score of Epworth Sleepiness Scale (ESS) on the morning after they completed PSG. The relationship between tongue fat content and severity of OSA as well as the association between tongue fat content in pre-operation and surgical efficacy were analyzed.Participants underwent UPPP and followed up at 3rd month after surgery, and they were divided into two groups according to the surgical efficacy.

Results

There were 7 patients in the moderate OSA group and 45 patients in the severe OSA group. The tongue volume was significantly larger in the severe OSA group than that in the moderate OSA group. There was no difference in tongue fat volume and tongue fat rate between the two groups. There was no association among tongue fat content, AHI, obstructive apnea hypopnea index, obstructive apnea index and Epworth sleepiness scale (all P > 0.05), but tongue fat content was related to the lowest oxygen saturation (r=-0.335, P < 0.05). There was no significantly difference in pre-operative tongue fat content in two different surgical efficacy groups.

Conclusions

This study didn’t show an association between tongue fat content and the severity of OSA in the Chinese group, but it suggested a negative correlation between tongue fat content and the lowest oxygen saturation (LSaO2). Tongue fat content didn’t influence surgical efficacy of UPPP in Chinese OSA patients.

Trial registration

This study didn’t report on a clinical trial, it was retrospectively registered.
Appendix
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Metadata
Title
The relationship of tongue fat content and efficacy of uvulopalatopharyngoplasty in Chinese patients with obstructive sleep apnea
Authors
Bingjie Zhao
Zine Cao
Yushan Xie
Yewen Shi
Yitong Zhang
Shiyu Liu
Xi Chen
Lina Ma
Xiaoxin Niu
Yonglong Su
Yani Feng
Chunfeng Lian
Xiaoyong Ren
Haiqin Liu
Publication date
01-12-2023
Publisher
BioMed Central
Published in
BMC Surgery / Issue 1/2023
Electronic ISSN: 1471-2482
DOI
https://doi.org/10.1186/s12893-023-02144-x

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