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01-04-2010 | Short Communication

Lidocaine pretreatment reduces the frequency and severity of myoclonus induced by etomidate

Authors: Fethi Gultop, Taylan Akkaya, Nurdan Bedirli, Haluk Gumus

Published in: Journal of Anesthesia | Issue 2/2010

Abstract

The objective of this study was to assess the effects of lidocaine on the incidence and severity of myoclonic movements induced by etomidate. Sixty patients were randomly assigned to receive either 20 mg lidocaine or saline (n = 30, each), 30 s before administration of etomidate (0.3 mg/kg). One minute after etomidate administration we assessed severity of myoclonus. Pretreatment with lidocaine significantly reduced both the incidence and severity of myoclonic movements. As a conclusion, lidocaine is an effective and safe drug to reduce the etomidate-induced myoclonus without significant side effects.

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Title: Lidocaine pretreatment reduces the frequency and severity of myoclonus induced by etomidate
Authors: Fethi Gultop
Taylan Akkaya
Nurdan Bedirli
Haluk Gumus
Publication date: 01-04-2010
Publisher: Springer Japan
Published in: Journal of Anesthesia / Issue 2/2010
Print ISSN: 0913-8668
Electronic ISSN: 1438-8359
DOI: https://doi.org/10.1007/s00540-010-0869-6

At a glance: The STEP trials

Springer Medicine

Lidocaine pretreatment reduces the frequency and severity of myoclonus induced by etomidate

Abstract

At a glance: The STEP trials

Springer Medicine

Abstract

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