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Critical Care
Published in: Critical Care 1/2011

Open Access 01-02-2011 | Poster presentation

Levosimendan in trauma patients with acute cardiac failure

Authors: AN Afonin, N Karpun

Published in: Critical Care | Special Issue 1/2011

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Excerpt

Acute heart failure (AHF) is common among trauma patients with pre-existing coronary artery disease (CAD) and myocardial perfusion defect. The therapy is aimed at increased contractility while decreasing afterload and includes β1-adrenergic agents and phosphodiesterase III inhibitors, which act by increasing the intracellular calcium (Ca) concentration, thus markedly increasing myocardial energy consumption and risk of arrhythmias. The new Ca sensitizer levosimendan enhances cardiac performance without increasing myocardial energy demand and oxygen consumption. We report new use of levosimendan in polytrauma victims with AHF. …
Literature
1.
Metadata
Title
Levosimendan in trauma patients with acute cardiac failure
Authors
AN Afonin
N Karpun
Publication date
01-02-2011
Publisher
BioMed Central
Published in
Critical Care / Issue Special Issue 1/2011
Electronic ISSN: 1364-8535
DOI
https://doi.org/10.1186/cc9514

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