Letter to the Editor regarding “PET: Is myocardial flow quantification a clinical reality?”

Excerpt

We enjoyed the excellent review article recently published by Saraste et al1 on quantitative flow using cardiac positron emission tomography (PET). Specifically, its Table 1 provides an in-depth comparison of current software tools for quantifying absolute flow and coronary flow reserve (CFR). Recently, the Food and Drug Administration (FDA) issued 510(k) approval2 of a new program called cfrQuant that was developed by us. It uses an integrative model based on retention kinetics for either Rb-82 or N-13 ammonia previously validated against electromagnetic flow meters in dogs.3 …