Skip to main content
Top
Published in: Journal of Medical Case Reports 1/2009

Open Access 01-12-2009 | Case report

Lemierre's syndrome resulting from streptococcal induced otitis media and mastoiditis: a case report

Authors: Che M Harris, Micean Johnikin, Hope Rhodes, Theresa Fuller, Sohail R Rana, Hasan Nabhani, Dulara Hussain, Mohan Kurukumbi, Annapurni Jayam-Trouth, Jhansi Gajjala, Faria Farhat, Vinod Mody

Published in: Journal of Medical Case Reports | Issue 1/2009

Login to get access

Abstract

Introduction

Lemierre's syndrome is an extremely rare and almost universally fatal disease characterized as thrombophlebitis of the internal jugular venous system with subsequent metastatic infection. Fusobacterium necrophorum is the most common organism implicated in causation of Lemierre's syndrome. Group A Streptococcus has mainly been observed as a polymicrobial organism in the syndrome. We report a rare finding of a rare disease where Group A Streptococcus was the sole organism triggering Lemierre's syndrome. To our knowledge, this is only the third recorded patient with such an occurrence.

Case presentation

We describe a 9-year-old African American boy, who presented with otitis media and mastoiditis that culminated in Lemierre's syndrome. Isolates bore only Group A Streptococcus. The patient was appropriately treated and responded with full recovery from the syndrome.

Conclusion

Since Lemierre's syndrome is classically detected by clinical diagnosis, these findings should prompt clinicians to consider Group A Streptococcus as an alternative catalyst. It should be pondered that patients who present with typical Group A streptococcal infections have the possibility for developing Lemierre's syndrome. Though this complication appears to be rare, early diagnosis and prompt intervention have proven critical in survival outcome. Indeed, what would seem to be a routine case of strep throat or otitis media easily treated with antibiotics could end up being an unalterable progression to death unless Lemierre's syndrome is immediately diagnosed and treated.
Literature
1.
go back to reference Goldenberg NA, Knapp-Clevenger R, Hays T, Manco-Johnson MJ: Lemierre's and Lemierre's-like syndromes in children: survival and thromboembolic outcomes. Pediatrics. 2005, 116: e543-e548. 10.1542/peds.2005-0433.CrossRefPubMed Goldenberg NA, Knapp-Clevenger R, Hays T, Manco-Johnson MJ: Lemierre's and Lemierre's-like syndromes in children: survival and thromboembolic outcomes. Pediatrics. 2005, 116: e543-e548. 10.1542/peds.2005-0433.CrossRefPubMed
2.
go back to reference Lemierre A: On certain septicemias due to anaerobic organisms. Lancet. 1936, 1: 701-703. 10.1016/S0140-6736(00)57035-4.CrossRef Lemierre A: On certain septicemias due to anaerobic organisms. Lancet. 1936, 1: 701-703. 10.1016/S0140-6736(00)57035-4.CrossRef
3.
go back to reference Giridharan W, De S, Osman EZ, Amma L, Hughes J, McCormick MS: Complicated otitis media caused by Fusobacterium necrophorum. Otology. 2004, 118: 50-53. Giridharan W, De S, Osman EZ, Amma L, Hughes J, McCormick MS: Complicated otitis media caused by Fusobacterium necrophorum. Otology. 2004, 118: 50-53.
4.
go back to reference Shah SA, Ghani R: Lemierre's syndrome: a forgotten complication of oropharyngeal infection. J Ayub Med Coll Abottabad. 2005, 17: 30-33. Shah SA, Ghani R: Lemierre's syndrome: a forgotten complication of oropharyngeal infection. J Ayub Med Coll Abottabad. 2005, 17: 30-33.
5.
go back to reference Bliss SJ, Flanders SA, Saint S: A pain in the neck. NEJM. 2004, 350: 1037-1042. 10.1056/NEJMcps032253.CrossRefPubMed Bliss SJ, Flanders SA, Saint S: A pain in the neck. NEJM. 2004, 350: 1037-1042. 10.1056/NEJMcps032253.CrossRefPubMed
6.
go back to reference Baig MA, Rasheed J, Subkowitz D, Vieira J: A review of Lemierre syndrome. Internet J Infect Dis. 2006, 5: Baig MA, Rasheed J, Subkowitz D, Vieira J: A review of Lemierre syndrome. Internet J Infect Dis. 2006, 5:
7.
go back to reference Wilson P, Tierney L: Lemierre syndrome caused by Streptococcus pyogenes. Clin Infect Dis. 2005, 41: 1208-1209. 10.1086/444565.CrossRefPubMed Wilson P, Tierney L: Lemierre syndrome caused by Streptococcus pyogenes. Clin Infect Dis. 2005, 41: 1208-1209. 10.1086/444565.CrossRefPubMed
8.
go back to reference Anton E: Lemierre syndrome caused by Streptococcus pyogenes in an elderly man. Lancet Infect Dis. 2007, 7: 233-10.1016/S1473-3099(07)70055-5.CrossRefPubMed Anton E: Lemierre syndrome caused by Streptococcus pyogenes in an elderly man. Lancet Infect Dis. 2007, 7: 233-10.1016/S1473-3099(07)70055-5.CrossRefPubMed
Metadata
Title
Lemierre's syndrome resulting from streptococcal induced otitis media and mastoiditis: a case report
Authors
Che M Harris
Micean Johnikin
Hope Rhodes
Theresa Fuller
Sohail R Rana
Hasan Nabhani
Dulara Hussain
Mohan Kurukumbi
Annapurni Jayam-Trouth
Jhansi Gajjala
Faria Farhat
Vinod Mody
Publication date
01-12-2009
Publisher
BioMed Central
Published in
Journal of Medical Case Reports / Issue 1/2009
Electronic ISSN: 1752-1947
DOI
https://doi.org/10.1186/1752-1947-3-6658

Other articles of this Issue 1/2009

Journal of Medical Case Reports 1/2009 Go to the issue