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Published in: Archives of Gynecology and Obstetrics 1/2010

01-01-2010 | Case Report

Leiomyomatosis peritonealis disseminata in a pregnant woman

Authors: Birte Summa, Christian Schem, Marion Weigel, Alexander Strauss, Walter Jonat, Nicolai Maass, Fritz Schäfer, Dirk O. Bauerschlag

Published in: Archives of Gynecology and Obstetrics | Issue 1/2010

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Abstract

Background

Leiomyomatosis peritonealis disseminata (LPD) is a rare disease occurring as intraabdominal benign tumors. The underlying mechanism of LPD development in premenopausal females is still unknown, but high levels of estrogen and progesterone seem to play a major role.

Case

We present a case of a 29-year-old gravida 1, 22 6/7 weeks of gestation with symptoms of an acute abdomen. Abdominal ultrasound and MRI showed intraabdominal masses of uncertain origin most likely to be an extreme example of pseudomyxoma peritonei. Explorative laparotomy was performed, and histopathological analysis revealed benign tumors classified as leiomyomatosis. A cesarean section was performed due to increasing abdominal pain and excessive elevated inflammatory serum parameters. Postpartum, a spontaneous regression of the LPD was marked.

Conclusion

LPD is a rare disease of young women. Excessive hormonal exposure seems to play a major role. Diagnosis is often difficult and a histopathological analysis is needed.
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Metadata
Title
Leiomyomatosis peritonealis disseminata in a pregnant woman
Authors
Birte Summa
Christian Schem
Marion Weigel
Alexander Strauss
Walter Jonat
Nicolai Maass
Fritz Schäfer
Dirk O. Bauerschlag
Publication date
01-01-2010
Publisher
Springer-Verlag
Published in
Archives of Gynecology and Obstetrics / Issue 1/2010
Print ISSN: 0932-0067
Electronic ISSN: 1432-0711
DOI
https://doi.org/10.1007/s00404-009-1074-4

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