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Head and Neck Pathology
Published in: Head and Neck Pathology 2/2019

01-06-2019 | Case Report

Laugier–Hunziker Syndrome Presenting with Metachronous Melanoacanthomas

Authors: Hattan Zaki, Amarpreet Sabharwal, Jill Kramer, Alfredo Aguirre

Published in: Head and Neck Pathology | Issue 2/2019

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Abstract

Laugier–Hunziker syndrome (LHS, also termed idiopathic lenticular mucocutaneous hyperpigmentation) is an unusual condition characterized by progressive pigmentation of the mucous membranes. LHS displays a benign course and is not associated with malignancy. Here we present a case of LHS with a 7-year follow-up. We document metachronous oral melanoacanthomas in this individual. In addition, we found that the oral melanotic macules in this patient waxed and waned in a cyclical manner. To our knowledge, this is the first report of these findings in the context of LHS. Finally, we provide an overview of other conditions that can present with mucosal hyperpigmentation. It is critical to distinguish LHS from other conditions characterized by mucosal pigmentation in order to facilitate optimal patient care.
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Metadata
Title
Laugier–Hunziker Syndrome Presenting with Metachronous Melanoacanthomas
Authors
Hattan Zaki
Amarpreet Sabharwal
Jill Kramer
Alfredo Aguirre
Publication date
01-06-2019
Publisher
Springer US
Published in
Head and Neck Pathology / Issue 2/2019
Electronic ISSN: 1936-0568
DOI
https://doi.org/10.1007/s12105-018-0897-3

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