Skip to main content
Top
Published in: Surgical Endoscopy 9/2015

01-09-2015 | Dynamic Manuscript

Lateral approach in laparoscopic distal pancreatectomy is safe and potentially beneficial compared to the traditional medial approach

Authors: Matt Strickland, Julie Hallet, Daniel Abramowitz, Shuyin Liang, Calvin H. L. Law, Shiva Jayaraman

Published in: Surgical Endoscopy | Issue 9/2015

Login to get access

Abstract

Introduction

Laparoscopic distal pancreatectomy has become widely accepted for the treatment of left-sided pancreatic lesions. Traditionally, a medial laparoscopic distal pancreatectomy (MDLP) has been employed, with division of the gland followed by medial to lateral mobilization. Recent technical reports of lateral laparoscopic distal pancreatectomy (LLDP) suggest that it offers easier access and more precise dissection. Data on this technique remain sparse and inconclusive, with no formal comparison with MLDP. We sought to compare outcomes of LLDP to MLDP.

Methods

We reviewed the charts of patients undergoing laparoscopic distal pancreatectomy at two academic institutions, from July 2009 to June 2013. Primary outcomes were operating time and estimated blood loss. Secondary outcomes included success of spleen-preserving procedures, length of sacrificed pancreas parenchyma, margins status, 30-day major morbidity (Clavien grade 3–5 complications), and length of stay. We reported data as proportions and medians. We performed comparative analysis using Chi square test or Fisher’s exact test for categorical variables, and Mann–Whitney U test for continuous variables.

Results

We retrieved 43 cases (19 LLDP, 24 MLDP). Median operative time was shorter (166 vs 190 min; p = 0.03) and estimated blood loss lower (50 vs 250 mL; p < 0.01) with LLDP. No margin was positive with LLDP compared to 2 (8.3 %) with MLDP. Major morbidity did not differ (LLDP 21.0 % vs MLDP 25.0 %; p = 0.76). Trends toward lower conversion rate (16.7 vs 5.3 %; p = 0.36) and shorter length of stay (5 vs 4 days; p = 0.35) were not significant.

Conclusion

LLDP is a feasible and safe approach for distal lesions of the pancreatic tail, associated with shorter operative time and decreased blood loss compared to traditional MLDP. Potential of decreased conversion rate and length of stay exists. These hypotheses need to be confirmed in larger prospective studies.
Appendix
Available only for authorised users
Literature
1.
go back to reference Kooby DA, Gillespie T, Bentrem D, Nakeeb A, Schmidt MC, Merchant NB et al (2008) Left-sided pancreatectomy. Ann Surg 126:88–96 Kooby DA, Gillespie T, Bentrem D, Nakeeb A, Schmidt MC, Merchant NB et al (2008) Left-sided pancreatectomy. Ann Surg 126:88–96
2.
go back to reference Lebedyev A, Zmora O, Kuriansky J, Rosin D, Khaikin M, Shabtai M et al (2004) Laparoscopic distal pancreatectomy. Surg Endosc 18(10):1427–1430CrossRefPubMed Lebedyev A, Zmora O, Kuriansky J, Rosin D, Khaikin M, Shabtai M et al (2004) Laparoscopic distal pancreatectomy. Surg Endosc 18(10):1427–1430CrossRefPubMed
3.
go back to reference Jayaraman S, Gonen M, Brennan MF, D’Angelica MI, DeMatteo RP, Fong Y, Jarnagin WR, Allen PJ (2010) J Am Coll Surg 211(4):503–509CrossRefPubMed Jayaraman S, Gonen M, Brennan MF, D’Angelica MI, DeMatteo RP, Fong Y, Jarnagin WR, Allen PJ (2010) J Am Coll Surg 211(4):503–509CrossRefPubMed
4.
go back to reference Thomas JK, Abraham D, Joseph P, Paul MJ (2012) Lateral laparoscopic approach to pancreatic tail insulinomas. World J Endocr Surg 4(1):3–7 Thomas JK, Abraham D, Joseph P, Paul MJ (2012) Lateral laparoscopic approach to pancreatic tail insulinomas. World J Endocr Surg 4(1):3–7
5.
go back to reference Honore C, Honore P, Meurisse M (2007) Laparoscopic spleen-preserving distal pancreatectomy: description of an original posterior approach. J Laparoendosc Adv Surg Technol 17(5):686–689CrossRef Honore C, Honore P, Meurisse M (2007) Laparoscopic spleen-preserving distal pancreatectomy: description of an original posterior approach. J Laparoendosc Adv Surg Technol 17(5):686–689CrossRef
6.
go back to reference Nakamura M, Nagayoshi Y, Kono H et al (2011) Lateral approach for laparoscopic splenic vessel-preserving distal pancreatectomy. Surgery 150(2):326–331CrossRefPubMed Nakamura M, Nagayoshi Y, Kono H et al (2011) Lateral approach for laparoscopic splenic vessel-preserving distal pancreatectomy. Surgery 150(2):326–331CrossRefPubMed
7.
go back to reference Boutros C, Espat NJ, Somasundar P (2010) Completely laparoscopic subtotal pancreatectomy with splenic artery preservation. J Gastrointest Surg 14(1):171–174CrossRefPubMed Boutros C, Espat NJ, Somasundar P (2010) Completely laparoscopic subtotal pancreatectomy with splenic artery preservation. J Gastrointest Surg 14(1):171–174CrossRefPubMed
8.
go back to reference Suzuki O, Tanaka E, Hirano S, Suzuoki M, Hashida H, Ichimura T et al (2009) Efficacy of the electrothermal bipolar vessel sealer in laparoscopic spleen-preserving distal pancreatectomy with conservation of the splenic artery and vein. J Gastrointest Surg 13(1):155–158CrossRefPubMed Suzuki O, Tanaka E, Hirano S, Suzuoki M, Hashida H, Ichimura T et al (2009) Efficacy of the electrothermal bipolar vessel sealer in laparoscopic spleen-preserving distal pancreatectomy with conservation of the splenic artery and vein. J Gastrointest Surg 13(1):155–158CrossRefPubMed
9.
go back to reference Melotti G, Butturini G, Piccoli M, Casetti L, Bassi C, Mullineris B et al (2007) Laparoscopic distal pancreatectomy: results on a consecutive series of 58 patients. Ann Surg 246(1):77–82PubMedCentralCrossRefPubMed Melotti G, Butturini G, Piccoli M, Casetti L, Bassi C, Mullineris B et al (2007) Laparoscopic distal pancreatectomy: results on a consecutive series of 58 patients. Ann Surg 246(1):77–82PubMedCentralCrossRefPubMed
10.
go back to reference Dindo D, Demartines N, Clavien PA (2004) Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey. Ann Surg 240:205–213PubMedCentralCrossRefPubMed Dindo D, Demartines N, Clavien PA (2004) Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey. Ann Surg 240:205–213PubMedCentralCrossRefPubMed
11.
go back to reference Bassi C, Dervenis C, Butturini G, Fingerhut A, Yeo C, Izbicki J et al (2005) International Study Group on Pancreatic Fistula. Postoperative pancreatic fistula: an international study group (ISGPF) definition. Surgery 138:8–13CrossRefPubMed Bassi C, Dervenis C, Butturini G, Fingerhut A, Yeo C, Izbicki J et al (2005) International Study Group on Pancreatic Fistula. Postoperative pancreatic fistula: an international study group (ISGPF) definition. Surgery 138:8–13CrossRefPubMed
12.
go back to reference Charlson M, Pompei P, Ales K, MacKenzie C (1987) A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis 40:373–383CrossRefPubMed Charlson M, Pompei P, Ales K, MacKenzie C (1987) A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis 40:373–383CrossRefPubMed
13.
go back to reference Soper NJ, Brunt LM, Dunnegan DL, Meininger TA (1994) Laparoscopic distal pancreatectomy in the porcine model. Surg Endosc 8:57–60CrossRefPubMed Soper NJ, Brunt LM, Dunnegan DL, Meininger TA (1994) Laparoscopic distal pancreatectomy in the porcine model. Surg Endosc 8:57–60CrossRefPubMed
14.
go back to reference Takada M, Ichihara T, Toyama H, Suzuki Y, Kuroda Y (2004) Retroperitoneoscopic laparoscopic distal pancreatectomy with spleen salvage. Hepatogastroenterology 51:925–927PubMed Takada M, Ichihara T, Toyama H, Suzuki Y, Kuroda Y (2004) Retroperitoneoscopic laparoscopic distal pancreatectomy with spleen salvage. Hepatogastroenterology 51:925–927PubMed
15.
go back to reference Shinchi H, Takao S, Noma H, Mataki Y, Iino S, Aikou T (2001) Hand-assisted laparoscopic distal pancreatectomy with minilaparotomy for distal pancreatic cystadenoma. Surg Laparosc Endosc Percutan Technol 11:139–143 Shinchi H, Takao S, Noma H, Mataki Y, Iino S, Aikou T (2001) Hand-assisted laparoscopic distal pancreatectomy with minilaparotomy for distal pancreatic cystadenoma. Surg Laparosc Endosc Percutan Technol 11:139–143
16.
go back to reference Yoon YS, Lee KH, Han HS, Cho JY, Ahn KS (2009) Patency of splenic vessels after laparoscopic spleen and splenic vessel-preserving distal pancreatectomy. Br J Surg 96:633–640CrossRefPubMed Yoon YS, Lee KH, Han HS, Cho JY, Ahn KS (2009) Patency of splenic vessels after laparoscopic spleen and splenic vessel-preserving distal pancreatectomy. Br J Surg 96:633–640CrossRefPubMed
17.
go back to reference Adam JP, Jacquin A, Laurent C, Collet D, Masson B, Fernández-Cruz L et al (2013) Laparoscopic spleen-preserving distal pancreatectomy: splenic vessel preservation compared with the Warshaw technique. JAMA Surg 148(3):246–252CrossRef Adam JP, Jacquin A, Laurent C, Collet D, Masson B, Fernández-Cruz L et al (2013) Laparoscopic spleen-preserving distal pancreatectomy: splenic vessel preservation compared with the Warshaw technique. JAMA Surg 148(3):246–252CrossRef
Metadata
Title
Lateral approach in laparoscopic distal pancreatectomy is safe and potentially beneficial compared to the traditional medial approach
Authors
Matt Strickland
Julie Hallet
Daniel Abramowitz
Shuyin Liang
Calvin H. L. Law
Shiva Jayaraman
Publication date
01-09-2015
Publisher
Springer US
Published in
Surgical Endoscopy / Issue 9/2015
Print ISSN: 0930-2794
Electronic ISSN: 1432-2218
DOI
https://doi.org/10.1007/s00464-014-3997-5

Other articles of this Issue 9/2015

Surgical Endoscopy 9/2015 Go to the issue