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Published in: European Archives of Oto-Rhino-Laryngology 9/2011

01-09-2011 | Rhinology

Laser and topical mitomycin C for management of nasal synechia after FESS: a preliminary report

Authors: Ahmed Hesham, Ahmed Fathi, Mahmoud Attia, Sherif Safwat, Ahmed Hesham

Published in: European Archives of Oto-Rhino-Laryngology | Issue 9/2011

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Abstract

The objective of the study is to assess the role of diode laser coupled with topical mitomycin C (MMC) in the management of synechia after endoscopic sinus surgery. Twenty-five patients with recurrent sinusitis due to synechia between the middle turbinate and lateral nasal wall after endoscopic sinus surgery were included in this study. Diode laser was used to divide the synechia and MMC was applied topically in the area of the middle meatus for 5 min. Patients were followed for 6 months to assess symptoms improvement, recurrence of synechia and CT scan changes. Most of our patients reported improvement of their symptoms, recurrent synechia occurred in 15% of the patients with significant improvement of the CT scan findings. In conclusion, the diode laser with topical MMC is an outpatient procedure which is simple, safe and effective in managing postoperative nasal synechia.
Literature
1.
go back to reference Fernandes SV (1999) Postoperative care in functional endoscopic sinus surgery. Laryngoscope 109:945–948PubMedCrossRef Fernandes SV (1999) Postoperative care in functional endoscopic sinus surgery. Laryngoscope 109:945–948PubMedCrossRef
2.
go back to reference Gross RD, Sheridan MF, Burgess LP (1997) Endoscopic sinus surgery complications in residency. Laryngoscope 107:1080–1085PubMedCrossRef Gross RD, Sheridan MF, Burgess LP (1997) Endoscopic sinus surgery complications in residency. Laryngoscope 107:1080–1085PubMedCrossRef
3.
go back to reference Van Duyne J, Coleman JA Jr (1995) Treatment of nasopharyngeal inlet stenosis following uvulopalatopharyngoplasty with the CO2 laser. Laryngoscope 105:914–918PubMedCrossRef Van Duyne J, Coleman JA Jr (1995) Treatment of nasopharyngeal inlet stenosis following uvulopalatopharyngoplasty with the CO2 laser. Laryngoscope 105:914–918PubMedCrossRef
4.
go back to reference Levine HL (1989) Endoscopy and the KTP/532 laser for nasal sinus disease. Ann Otol Rhinol Laryngol 98:46–51PubMed Levine HL (1989) Endoscopy and the KTP/532 laser for nasal sinus disease. Ann Otol Rhinol Laryngol 98:46–51PubMed
5.
go back to reference Feyh J (1995) Endoscopic surgery of the nose and paranasal sinuses with the aid of the holmium:YAG laser. Adv Otorhinolaryngol 49:122–124PubMed Feyh J (1995) Endoscopic surgery of the nose and paranasal sinuses with the aid of the holmium:YAG laser. Adv Otorhinolaryngol 49:122–124PubMed
6.
go back to reference Muntz HR (1987) Pitfalls to laser correction of choanal atresia. Ann Otol Rhinol Laryngol 96:43–46PubMed Muntz HR (1987) Pitfalls to laser correction of choanal atresia. Ann Otol Rhinol Laryngol 96:43–46PubMed
7.
go back to reference Costa VP, Spaeth GL, Eiferman RA et al (1993) Wound healing modulation in glaucoma filtration surgery. Ophthalmic Surg 24:152–166PubMed Costa VP, Spaeth GL, Eiferman RA et al (1993) Wound healing modulation in glaucoma filtration surgery. Ophthalmic Surg 24:152–166PubMed
8.
go back to reference Majmudar PA, Forstot SL, Dennis RF et al (2000) Topical mitomycin C for subepithelial fibrosis after refractive corneal surgery. Ophthalmology 107:89–94PubMedCrossRef Majmudar PA, Forstot SL, Dennis RF et al (2000) Topical mitomycin C for subepithelial fibrosis after refractive corneal surgery. Ophthalmology 107:89–94PubMedCrossRef
9.
go back to reference Correa AJ, Reinisch L, Sanders DL et al (1999) Inhibition of subglottic stenosis with mitomycin C in the canine model. Ann Otol Rhinol Laryngol 108:1053–1060PubMed Correa AJ, Reinisch L, Sanders DL et al (1999) Inhibition of subglottic stenosis with mitomycin C in the canine model. Ann Otol Rhinol Laryngol 108:1053–1060PubMed
10.
go back to reference Tom LWC, Palasti S, Potsic WP et al (1997) The effects of gelatin film stents in the middle meatus. Am J Rhinol 229–232 Tom LWC, Palasti S, Potsic WP et al (1997) The effects of gelatin film stents in the middle meatus. Am J Rhinol 229–232
11.
go back to reference Friedman M, Landsberg R, Tanyeri H (2000) Middle turbinate medialization and preservation in endoscopic sinus surgery. Otolaryngol Head Neck Surg 123:76–80PubMedCrossRef Friedman M, Landsberg R, Tanyeri H (2000) Middle turbinate medialization and preservation in endoscopic sinus surgery. Otolaryngol Head Neck Surg 123:76–80PubMedCrossRef
12.
go back to reference Miller RS, Steward DL, Tami TA et al (2003) The clinical effects of hyaluronic acid ester nasal dressing (Merogel) on intranasal wound healing after functional endoscopic sinus surgery. Otolaryngol Head Neck Surg 128(6):862–869PubMedCrossRef Miller RS, Steward DL, Tami TA et al (2003) The clinical effects of hyaluronic acid ester nasal dressing (Merogel) on intranasal wound healing after functional endoscopic sinus surgery. Otolaryngol Head Neck Surg 128(6):862–869PubMedCrossRef
13.
go back to reference Chung JH, Cosenza MJ, Rahbar R, Metson RB (2002) Mitomycin C for the prevention of adhesion formation after endoscopic sinus surgery: a randomized, controlled study. Otolaryngol Head Neck Surg 126(5):468–474PubMedCrossRef Chung JH, Cosenza MJ, Rahbar R, Metson RB (2002) Mitomycin C for the prevention of adhesion formation after endoscopic sinus surgery: a randomized, controlled study. Otolaryngol Head Neck Surg 126(5):468–474PubMedCrossRef
14.
go back to reference Lee JY, Lee SW (2007) Preventing lateral synechia formation after endoscopic sinus surgery with a silastic sheet. Arch Otolaryngol Head Neck Surg 133(8):776–779PubMedCrossRef Lee JY, Lee SW (2007) Preventing lateral synechia formation after endoscopic sinus surgery with a silastic sheet. Arch Otolaryngol Head Neck Surg 133(8):776–779PubMedCrossRef
15.
go back to reference Shrime MG, Tabaee A, Hsu AK et al (2007) Synechia formation after endoscopic sinus surgery and middle turbinate medialization with and without FloSeal. Am J Rhinol 21(2):174–179PubMedCrossRef Shrime MG, Tabaee A, Hsu AK et al (2007) Synechia formation after endoscopic sinus surgery and middle turbinate medialization with and without FloSeal. Am J Rhinol 21(2):174–179PubMedCrossRef
16.
go back to reference Konstantinidis I, Tsakiropoulou E, Vital I et al (2008) Intra- and postoperative application of mitomycin C in the middle meatus reduces adhesions and antrostomy stenosis after FESS. Rhinology 46(2):107–111PubMed Konstantinidis I, Tsakiropoulou E, Vital I et al (2008) Intra- and postoperative application of mitomycin C in the middle meatus reduces adhesions and antrostomy stenosis after FESS. Rhinology 46(2):107–111PubMed
17.
go back to reference Anand VK, Tabaee A, Kacker A et al (2004) The role of mitomycin C in preventing synechia and stenosis after endoscopic sinus surgery. Am J Rhinol 18(5):311–314PubMed Anand VK, Tabaee A, Kacker A et al (2004) The role of mitomycin C in preventing synechia and stenosis after endoscopic sinus surgery. Am J Rhinol 18(5):311–314PubMed
18.
go back to reference Kao SCS, Liao CL, Tseng JHS et al (1996) Dacryocystorhinostomy with intraoperative mitomycin C. Ophthalmology 104:86–91 Kao SCS, Liao CL, Tseng JHS et al (1996) Dacryocystorhinostomy with intraoperative mitomycin C. Ophthalmology 104:86–91
19.
go back to reference Hueman EM, Simpson CB (2005) Airway complications from topical mitomycin C. Otolaryngol Head Neck Surg 133:831–835PubMedCrossRef Hueman EM, Simpson CB (2005) Airway complications from topical mitomycin C. Otolaryngol Head Neck Surg 133:831–835PubMedCrossRef
20.
go back to reference Hu D, Sires BS, Tong DC et al (2000) Effect of brief exposure to mitomycin C on cultured human nasal mucosa fibroblasts. Ophthal Plast Reconstr Surg 16:119–125PubMedCrossRef Hu D, Sires BS, Tong DC et al (2000) Effect of brief exposure to mitomycin C on cultured human nasal mucosa fibroblasts. Ophthal Plast Reconstr Surg 16:119–125PubMedCrossRef
Metadata
Title
Laser and topical mitomycin C for management of nasal synechia after FESS: a preliminary report
Authors
Ahmed Hesham
Ahmed Fathi
Mahmoud Attia
Sherif Safwat
Ahmed Hesham
Publication date
01-09-2011
Publisher
Springer-Verlag
Published in
European Archives of Oto-Rhino-Laryngology / Issue 9/2011
Print ISSN: 0937-4477
Electronic ISSN: 1434-4726
DOI
https://doi.org/10.1007/s00405-011-1587-x

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