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Head and Neck Pathology
Published in: Head and Neck Pathology 1/2018

01-03-2018 | Sine qua non Radiology-Pathology

Laryngotracheal Involvement in Systemic Light Chain Amyloidosis

Authors: Daniel T. Ginat, Jefree Schulte, Louis Portugal, Nicole A. Cipriani

Published in: Head and Neck Pathology | Issue 1/2018

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Abstract

Laryngotracheal amyloid deposition is an uncommon manifestation of systemic light chain amyloidosis. Diagnostic imaging, such as CT, is useful for suggesting the possibility of amyloidosis and delineating the extent of the lesions for surgical management; however, the diagnosis is confirmed with the histologic finding of amorphous eosinophilic material which stains positively for Congo red and may show apple green birefringence on polarization. These features are exemplified in this sine qua non radiology-pathology correlation article.
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Metadata
Title
Laryngotracheal Involvement in Systemic Light Chain Amyloidosis
Authors
Daniel T. Ginat
Jefree Schulte
Louis Portugal
Nicole A. Cipriani
Publication date
01-03-2018
Publisher
Springer US
Published in
Head and Neck Pathology / Issue 1/2018
Electronic ISSN: 1936-0568
DOI
https://doi.org/10.1007/s12105-017-0831-0

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