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European Archives of Oto-Rhino-Laryngology

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01-02-2018 | Laryngology

Laryngotracheal anomalies associated with esophageal atresia: importance of early diagnosis

Authors: Pierre Fayoux, Martin Morisse, Rony Sfeir, Laurent Michaud, Sam Daniel

Published in: European Archives of Oto-Rhino-Laryngology | Issue 2/2018

Abstract

Objective

Esophageal atresia (EA) is the most common congenital esophageal malformation. Airway pathology, in particular, tracheomalacia and laryngotracheal anomalies is a major cause of morbidity and mortalilty in patients with EA. The aim of this study was to report the incidence and type of laryngotracheal anomalies seen in a large series of patients with EA, and to evaluate their impact on the management of children with EA.

Study design

Retrospective study.

Materials and methods

Retrospective cohort including all patients referred to the EA National Reference Center from January 2002 to December 2014. Airway assessment was based on endoscopy performed before, during and/or after esophageal surgery.

Results

One-hundred and fifty-eight patients were included in the study. Endoscopy revealed tracheomalacia in 141 cases (89.2%) and other laryngotracheal anomalies in 43 patients (27.2%). Ninety-six patients (60.7%) presented with persistent respiratory symptoms, including acute life-threatening events in 21 cases, leading to death in 6 cases. A correlation was observed between degree of tracheal collapse and presence of acute life-threatening events. Laryngotracheal surgery was required in 35 cases (22%).

Conclusion

Laryngotracheal anomalies are frequently associated with EA and represent an important etiology of morbidity and mortality that can be prevented by early and systematic diagnosis and aggressive management. An early systematic endoscopic evaluation is recommended to coordinate the airway management with the EA surgery.

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Title: Laryngotracheal anomalies associated with esophageal atresia: importance of early diagnosis
Authors: Pierre Fayoux
Martin Morisse
Rony Sfeir
Laurent Michaud
Sam Daniel
Publication date: 01-02-2018
Publisher: Springer Berlin Heidelberg
Published in: European Archives of Oto-Rhino-Laryngology / Issue 2/2018
Print ISSN: 0937-4477
Electronic ISSN: 1434-4726
DOI: https://doi.org/10.1007/s00405-017-4856-5

At a glance: The STEP trials

Springer Medicine

Laryngotracheal anomalies associated with esophageal atresia: importance of early diagnosis

Abstract

Objective

Study design

Materials and methods

Results

Conclusion

At a glance: The STEP trials

Springer Medicine

Abstract

Objective

Study design

Materials and methods

Results

Conclusion

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