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Open Access 22-04-2024 | Laryngeal Cancer | REVIEW

Current Status of Partial Laryngeal Surgery for Advanced Laryngeal Cancer: When and Why?

Authors: Erika Crosetti, Marco Fantini, Ilaria Bertotto, Andy Bertolin, Giulia Arrigoni, Andrea Lorenzi, Giovanni Succo

Abstract

Purpose of Review

This paper aims to evaluate the evolution and current status of partial laryngeal surgery in the treatment of advanced laryngeal cancer (LC). Specifically, recent progress in the selection of both patients and tumors, together with surgical and rehabilitation innovations, have contributed to balancing oncological control with the maintenance of quality of life in naïve and radiorecurrent patients. The main aspect is represented by the recognized role of open partial horizontal laryngectomies (OPHLs) in this new era of laryngeal cancer treatment.

Recent Findings

Recent advancements highlight OPHLs’ efficacy for conservative management of intermediate to advanced stages of LC. Innovations such as supratracheal partial laryngectomy have expanded surgical options, offering a modular approach to complex cases. Improved understanding of tumor biology, enhanced imaging techniques, and more precise preoperative planning have led to better patient outcomes, emphasizing the importance of a conservative function-preserving surgical treatment. These advancements reflect a broader trend towards individualized treatment plans that prioritize both survival and quality of life.

Summary

OPHLs play an important role in current management of intermediate/advanced LC, effectively balancing oncological control with the preservation of laryngeal functions. Critical factors include meticulous patient and tumor selection, the impact of surgical and technological refinements on functional outcomes, and the necessity of a multidisciplinary approach in treatment planning. Current evidence justifies the use of these interventions in many intermediate T-stage laryngeal tumors, even at risk of upstaging on pathological examination. The oncological results, the preservation of laryngeal function and the laryngectomy-free survival achieved with OPHLs appear to be highly competitive with those of non surgical organ-preservation protocols, aiming to introduce a new standard in the LC treatment.

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Title: Current Status of Partial Laryngeal Surgery for Advanced Laryngeal Cancer: When and Why?
Authors: Erika Crosetti
Marco Fantini
Ilaria Bertotto
Andy Bertolin
Giulia Arrigoni
Andrea Lorenzi
Giovanni Succo
Publication date: 22-04-2024
Publisher: Springer US
Keywords: Laryngeal Cancer
Laryngeal Cancer
Laryngectomy
Laryngeal Surgery
Published in: Current Oncology Reports
Print ISSN: 1523-3790
Electronic ISSN: 1534-6269
DOI: https://doi.org/10.1007/s11912-024-01516-7

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