Skip to main content
Top
Published in: Surgical Endoscopy 6/2015

01-06-2015

Laparoscopic versus open Ladd’s procedure for intestinal malrotation in adults

Authors: Lane L. Frasier, Glen Leverson, Ankush Gosain, Jacob Greenberg

Published in: Surgical Endoscopy | Issue 6/2015

Login to get access

Abstract

Background

Intestinal malrotation results from errors in fetal intestinal rotation and fixation. While most patients are diagnosed in childhood, some present as adults. Laparoscopic Ladd’s procedure is an accepted alternative to laparotomy in children but has not been well-studied in adults. This study was designed to investigate outcomes for adults undergoing laparoscopic Ladd’s repair for malrotation.

Methods

We performed a single-institution retrospective chart review over 11 years. Data collected included patient age, details of pre-operative work-up and diagnosis, surgical management, complications, rates of re-operation, and symptom resolution. Patients were evaluated on an intent-to-treat basis based on their planned operative approach. Categorical data were analyzed using Fisher’s exact test. Continuous data were analyzed using Student’s t test.

Results

Twenty-two patients were identified (age range 18–63). Fifteen were diagnosed pre-operatively; of the remaining seven patients, four received an intra-operative malrotation diagnosis during elective surgery for another problem. Most had some type of pre-operative imaging, with computed tomography being the most common (77.3 %). Comparing patients on an intent-to-treat basis, the two groups were similar with respect to age, operative time, and estimated blood loss. Six patients underwent successful laparoscopic repair; three began laparoscopically but were converted to laparotomy. There was a statistically significant difference in hospital length of stay (LOS) (5.0 ± 2.5 days vs 11.6 ± 8.1 days, p = 0.0148) favoring the laparoscopic approach. Three patients required re-operation: two underwent side-to-side duodeno-duodenostomy and one underwent a re-do Ladd’s procedure. Ultimately, three (two laparoscopic, one open) had persistent symptoms of bloating (n = 2), constipation (n = 2), and/or pain (n = 1).

Conclusion

Laparoscopic repair appears to be safe and effective in adults. While a small sample size limits the power of this study, we found a statistically significant decrease in LOS and a trend toward decreased postoperative nasogastric decompression. There were no significant differences in complication rates, re-operation, or persistence of symptoms between groups.
Literature
1.
go back to reference Sato TT and Oldham KT (2011) Pediatric abdomen. In: Mulholland MW, Lillemoe KD, Doherty GM, Maier RV, Simeone DM, Upchurch GR Jr (eds) Editors Greenfield’s surgery scientific principles and practice, Wolters Kluwer Health/Lippincott Williams & Wilkins, Philadelphia Sato TT and Oldham KT (2011) Pediatric abdomen. In: Mulholland MW, Lillemoe KD, Doherty GM, Maier RV, Simeone DM, Upchurch GR Jr (eds) Editors Greenfield’s surgery scientific principles and practice, Wolters Kluwer Health/Lippincott Williams & Wilkins, Philadelphia
2.
go back to reference Ladd WE (1936) Surgical diseases of the alimentary tract in infants. N Engl J Med 215:705–708CrossRef Ladd WE (1936) Surgical diseases of the alimentary tract in infants. N Engl J Med 215:705–708CrossRef
3.
go back to reference Bass KD, Rothenberg SS, Change JHT (1998) Laparoscopic Ladd’s procedure in infants with malrotation. J Pediatr Surg 33:279–281CrossRefPubMed Bass KD, Rothenberg SS, Change JHT (1998) Laparoscopic Ladd’s procedure in infants with malrotation. J Pediatr Surg 33:279–281CrossRefPubMed
4.
go back to reference Mazziotti MV, Strasberg SM, Langer JC (1997) intestinal rotation abnormalities without volvulus: the role of laparoscopy. J Am Coll Surg 185:172–176CrossRefPubMed Mazziotti MV, Strasberg SM, Langer JC (1997) intestinal rotation abnormalities without volvulus: the role of laparoscopy. J Am Coll Surg 185:172–176CrossRefPubMed
5.
go back to reference Nehra D, Goldstein AM (2011) Intestinal malrotation: varied clinical presentation from infancy through adulthood. Surgery 149:386–393CrossRefPubMed Nehra D, Goldstein AM (2011) Intestinal malrotation: varied clinical presentation from infancy through adulthood. Surgery 149:386–393CrossRefPubMed
6.
go back to reference Durkin ET, Lund DP, Shaaban AF, Schurr MJ, Weber SM (2008) Age-related differences in diagnosis and morbidity of intestinal malrotation. J Am Coll Surg 206:658–663CrossRefPubMed Durkin ET, Lund DP, Shaaban AF, Schurr MJ, Weber SM (2008) Age-related differences in diagnosis and morbidity of intestinal malrotation. J Am Coll Surg 206:658–663CrossRefPubMed
7.
go back to reference Parker J, Reid G, Wong F (1999) Microlaparoscopic left upper quadrant entry in patients at high risk of periumbilical adhesions. Aust N Z J Obstet Gynaecol 39:88–92CrossRefPubMed Parker J, Reid G, Wong F (1999) Microlaparoscopic left upper quadrant entry in patients at high risk of periumbilical adhesions. Aust N Z J Obstet Gynaecol 39:88–92CrossRefPubMed
8.
go back to reference Tittel A, Treutner KH, Titkova S, Ottinger A, Schumpelick V (2001) Comparison of adhesion reformation after laparoscoic and conventional adhesiolysis in an animal model. Lengenbeck’s Arch Surg 386:141–145CrossRef Tittel A, Treutner KH, Titkova S, Ottinger A, Schumpelick V (2001) Comparison of adhesion reformation after laparoscoic and conventional adhesiolysis in an animal model. Lengenbeck’s Arch Surg 386:141–145CrossRef
9.
go back to reference Garrard CL, Clements RH, Nanney L, Davidson JM, Richards WO (1999) Adhesion formation is reduced after laparoscopic surgery. Surg Endosc 13:10–13CrossRefPubMed Garrard CL, Clements RH, Nanney L, Davidson JM, Richards WO (1999) Adhesion formation is reduced after laparoscopic surgery. Surg Endosc 13:10–13CrossRefPubMed
10.
go back to reference Krahenbuhl L, Schafer M, Kuzinkovas V, Renzulli P, Baer HU, Buchler MW (1998) Experimental study of adhesion formation in open and laparoscopic fundoplication. Br J Surg 85:826–830CrossRefPubMed Krahenbuhl L, Schafer M, Kuzinkovas V, Renzulli P, Baer HU, Buchler MW (1998) Experimental study of adhesion formation in open and laparoscopic fundoplication. Br J Surg 85:826–830CrossRefPubMed
11.
go back to reference Polymeneas G, Theodosopoulos T, Stamatiadis A, Kourias E (2001) A comparative study of postoperative adhesion formation after laparoscopic vs open cholecystectomy. Surg Endosc 15:41–43CrossRefPubMed Polymeneas G, Theodosopoulos T, Stamatiadis A, Kourias E (2001) A comparative study of postoperative adhesion formation after laparoscopic vs open cholecystectomy. Surg Endosc 15:41–43CrossRefPubMed
12.
go back to reference Hull TL, Joyce MR, Geisler DP, Coffey JC (2012) Adhesions after laparoscopic and open ileal pouch-anal anastomosis surgery for ulcerative colitis. Br J Surg 99:270–275CrossRefPubMed Hull TL, Joyce MR, Geisler DP, Coffey JC (2012) Adhesions after laparoscopic and open ileal pouch-anal anastomosis surgery for ulcerative colitis. Br J Surg 99:270–275CrossRefPubMed
13.
go back to reference Liang JT, Huang KC, Lai HS, Lee PH, Jeng YM (2007) Oncologic results of laparoscopic versus conventional open surgery for stage II or III left-sided colon cancers: a randomized controlled trial. Ann Surg Oncol 14:109–117CrossRefPubMed Liang JT, Huang KC, Lai HS, Lee PH, Jeng YM (2007) Oncologic results of laparoscopic versus conventional open surgery for stage II or III left-sided colon cancers: a randomized controlled trial. Ann Surg Oncol 14:109–117CrossRefPubMed
14.
go back to reference Klarenbeek BR, Bergamaschi R, Veenhof AAFA, van der Peet DL, van den Broek WT, de Lange ESM, Bemelman WA, Heres P, Lacy AM, Cuesta MA (2011) Laparoscopic versus open sigmoid resection for diverticular disease: follow-up assessment of the randomized control Sigma trial. Surg Endosc 25:1121–1126CrossRefPubMed Klarenbeek BR, Bergamaschi R, Veenhof AAFA, van der Peet DL, van den Broek WT, de Lange ESM, Bemelman WA, Heres P, Lacy AM, Cuesta MA (2011) Laparoscopic versus open sigmoid resection for diverticular disease: follow-up assessment of the randomized control Sigma trial. Surg Endosc 25:1121–1126CrossRefPubMed
15.
go back to reference Polle SW, Dunker MS, Slors JF, Sprangers MA, Cuesta MA, Gouma DJ, Bemelman WA (2007) Body image, cosmesis, quality of life, and functional outcome of hand-assisted laparoscopic versus open restorative proctocolectomy: long-term results of randomized trial. Surg Endosc 21:1301–1307CrossRefPubMed Polle SW, Dunker MS, Slors JF, Sprangers MA, Cuesta MA, Gouma DJ, Bemelman WA (2007) Body image, cosmesis, quality of life, and functional outcome of hand-assisted laparoscopic versus open restorative proctocolectomy: long-term results of randomized trial. Surg Endosc 21:1301–1307CrossRefPubMed
16.
go back to reference Chan KL, Hui WC, Tam PK (2005) Prospective randomized single-center, single-blind comparison of laparoscopic vs open repair of pediatric inguinal hernia. Surg Endosc 19:927–932CrossRefPubMed Chan KL, Hui WC, Tam PK (2005) Prospective randomized single-center, single-blind comparison of laparoscopic vs open repair of pediatric inguinal hernia. Surg Endosc 19:927–932CrossRefPubMed
17.
go back to reference Vignali A, De Nardi P, Ghirardelli L, De Palo S, Staudacher C (2013) Short and long-term outcomes of laparoscopic colectomy in obese patients. World J Gastroenterol 19:7405–7411CrossRefPubMedCentralPubMed Vignali A, De Nardi P, Ghirardelli L, De Palo S, Staudacher C (2013) Short and long-term outcomes of laparoscopic colectomy in obese patients. World J Gastroenterol 19:7405–7411CrossRefPubMedCentralPubMed
18.
go back to reference Matzke GM, Dozois EJ, Larson DW, Moir CR (2005) Surgical management of intestinal malrotation in adults: comparative results for open and laparoscopic Ladd procedures. Surg Endosc 19:1416–1419CrossRefPubMed Matzke GM, Dozois EJ, Larson DW, Moir CR (2005) Surgical management of intestinal malrotation in adults: comparative results for open and laparoscopic Ladd procedures. Surg Endosc 19:1416–1419CrossRefPubMed
19.
go back to reference Ferzli G, Shapiro K, Chaudry G, Patel S (2004) Laparoscopic extraperitoneal approach to acutely incarcerated inguinal hernia. Surg Endosc 18:228–231CrossRefPubMed Ferzli G, Shapiro K, Chaudry G, Patel S (2004) Laparoscopic extraperitoneal approach to acutely incarcerated inguinal hernia. Surg Endosc 18:228–231CrossRefPubMed
20.
go back to reference Hoffman A, Leshem E, Zmora O, Nachtomi O, Shabtai M, Ayalon A, Rosin D (2010) The combined laparoscopic approach for the treatment of incarcerated inguinal hernia. Surg Endosc 24:1815–1818CrossRefPubMed Hoffman A, Leshem E, Zmora O, Nachtomi O, Shabtai M, Ayalon A, Rosin D (2010) The combined laparoscopic approach for the treatment of incarcerated inguinal hernia. Surg Endosc 24:1815–1818CrossRefPubMed
21.
go back to reference Yang GPC, Chan CTY, Lai ECH, Chan OCY, Tang CN, Li MKW (2012) Laparoscopic versus open repair for strangulated groin hernias: 188 cases over 4 years. Asian J Endosc Surg 5:131–137CrossRefPubMed Yang GPC, Chan CTY, Lai ECH, Chan OCY, Tang CN, Li MKW (2012) Laparoscopic versus open repair for strangulated groin hernias: 188 cases over 4 years. Asian J Endosc Surg 5:131–137CrossRefPubMed
22.
go back to reference Levard H, Boudet M-J, Msika S, Molkhou J-M, Hay J-M, Laborde Y, Gillet M, Fingerhut A (2001) Laparoscopic treatment of acute small bowel obstruction: a multicentre retrospective study. Aust N Z J Obstet Gynaecol 71:641–646 Levard H, Boudet M-J, Msika S, Molkhou J-M, Hay J-M, Laborde Y, Gillet M, Fingerhut A (2001) Laparoscopic treatment of acute small bowel obstruction: a multicentre retrospective study. Aust N Z J Obstet Gynaecol 71:641–646
23.
go back to reference O’Connor DB, Winter DC (2012) The role of laparoscopy in the management of acute small-bowel obstruction: a review of over 2,000 cases. Surg Endosc 26:12–17CrossRefPubMed O’Connor DB, Winter DC (2012) The role of laparoscopy in the management of acute small-bowel obstruction: a review of over 2,000 cases. Surg Endosc 26:12–17CrossRefPubMed
24.
go back to reference Suter M, Zermatten P, Halkic N, Martinet O, Bettschart B (2000) Laparoscopic management of mechanical small bowel obstruction. Are there predictors of success or failure? Surg Endosc 14:478–1183CrossRefPubMed Suter M, Zermatten P, Halkic N, Martinet O, Bettschart B (2000) Laparoscopic management of mechanical small bowel obstruction. Are there predictors of success or failure? Surg Endosc 14:478–1183CrossRefPubMed
25.
go back to reference Turley RS, Barbas AS, Lidsky ME, Mantyh CR, Migaly J, Scarborough JE (2013) Laparoscopic versus open Hartmann procedure for the emergency treatment of diverticulitis: a propensity-matched analysis. Dis Colon Rectum 56:72–82CrossRefPubMed Turley RS, Barbas AS, Lidsky ME, Mantyh CR, Migaly J, Scarborough JE (2013) Laparoscopic versus open Hartmann procedure for the emergency treatment of diverticulitis: a propensity-matched analysis. Dis Colon Rectum 56:72–82CrossRefPubMed
Metadata
Title
Laparoscopic versus open Ladd’s procedure for intestinal malrotation in adults
Authors
Lane L. Frasier
Glen Leverson
Ankush Gosain
Jacob Greenberg
Publication date
01-06-2015
Publisher
Springer US
Published in
Surgical Endoscopy / Issue 6/2015
Print ISSN: 0930-2794
Electronic ISSN: 1432-2218
DOI
https://doi.org/10.1007/s00464-014-3849-3

Other articles of this Issue 6/2015

Surgical Endoscopy 6/2015 Go to the issue