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Published in:

01-10-2008

Laparoscopic surgery for rectal cancer: oncological results and clinical outcome of 225 patients

Authors: Ayman Agha, Alois Fürst, Johanna Hierl, Igors Iesalnieks, Gabriel Glockzin, Matthias Anthuber, Karl-Walter Jauch, Hans J. Schlitt

Published in: Surgical Endoscopy | Issue 10/2008

Abstract

Introduction

The efficacy and feasibility of laparoscopic resection for rectal cancer has been proved, but the results of prospective, randomized studies are not yet available. Here we present a prospective observational study evaluating oncological and clinical outcome after laparoscopic surgery in patients with rectal cancer.

Patients and Methods

Between January 1998 and March 2005, 225 patients with rectal adenocarcinoma underwent laparoscopic surgery at the University of Regensburg Medical Center. Clinical and oncological outcome of these patients including perioperative and long-term complications was evaluated. Survival curves were calculated according to the Kaplan–Meier method. Minimum follow-up was 24 months.

Results

The distribution of the International Union against Cancer (UICC) stages was: 37.7% stage I, 20.5% stage II, 24.9% stage III, and 16.9% stage IV. Local recurrence was diagnosed in 5.8% and distant metastases in 8.1% of cases after mean follow-up of 36.4 months. The 5-year overall survival rate was 75.7% after curative and 40.7% after palliative surgery (p < 0.05). The stage-related survival rates were 86.7% for UICC stage I, 61.7% for stage II, 68.1% for stage III, and 40.1% for stage IV.

Conclusions

Our results demonstrate the efficacy and technical feasibility of laparoscopic surgery for rectal cancer regarding the perioperative morbidity and the oncological outcome.

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Title: Laparoscopic surgery for rectal cancer: oncological results and clinical outcome of 225 patients
Authors: Ayman Agha
Alois Fürst
Johanna Hierl
Igors Iesalnieks
Gabriel Glockzin
Matthias Anthuber
Karl-Walter Jauch
Hans J. Schlitt
Publication date: 01-10-2008
Publisher: Springer-Verlag
Published in: Surgical Endoscopy / Issue 10/2008
Print ISSN: 0930-2794
Electronic ISSN: 1432-2218
DOI: https://doi.org/10.1007/s00464-008-0028-4

At a glance: The STEP trials

Springer Medicine

Laparoscopic surgery for rectal cancer: oncological results and clinical outcome of 225 patients

Abstract

Introduction

Patients and Methods

Results

Conclusions

At a glance: The STEP trials

Springer Medicine

Abstract

Introduction

Patients and Methods

Results

Conclusions

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