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Published in: Journal of Hepato-Biliary-Pancreatic Sciences 6/2009

01-11-2009 | Topics

Laparoscopic hepatectomy for liver tumors: proposals for standardization

Authors: Yuichiro Otsuka, Masaru Tsuchiya, Tetsuya Maeda, Toshio Katagiri, Jun Isii, Akira Tamura, Kunihiro Yamazaki, Yoshihisa Kubota, Takashi Suzuki, Takayuki Suzuki, Satoru Kagami, Hironori Kaneko

Published in: Journal of Hepato-Biliary-Pancreatic Sciences | Issue 6/2009

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Abstract

Background/purpose

We draw on our experience with laparoscopic hepatectomy (LH) to present recommendations for standardization of LH for the treatment of liver tumors.

Methods

At our center, 90 LHs were performed from April 1993 to January 2008. These were divided equally into early cases and late cases, and short-term postoperative results were compared. Forty-nine of the LH procedures were total-laparoscopic procedures, 16 were hand-assisted procedures, and 25 were laparoscopy-assisted procedures. The tumors were malignant in 76 cases and benign in 14 cases.

Results

Among late cases, the numbers of malignant tumors and tumors located in the posterosuperior region of the liver (Segments VII, VIII, and IVb) were significantly higher than among early cases; however, operative blood loss and postoperative hospital stay were significantly lower in the late cases (158.9 ± 213.4 vs. 377.6 ± 421.2 cc, P = 0.007; and 8.7 ± 3.6 vs. 15.3 ± 8.7 days, P = 0.0001, respectively). No operative deaths occurred in either group.

Conclusions

Although LH does have a steep learning curve, we believe that it can be standardized and provide a less invasive surgical option—with no reduction in disease curability—for the treatment of liver tumors in selected patients.
Literature
1.
go back to reference Reich H, McGlynn F, DeCaprio J, Budin R. Laparoscopic excision of benign liver lesions. Obstet Gynecol. 1991;78:956–8.PubMed Reich H, McGlynn F, DeCaprio J, Budin R. Laparoscopic excision of benign liver lesions. Obstet Gynecol. 1991;78:956–8.PubMed
2.
go back to reference Kaneko H, Takagi S, Shiba T. Laparoscopic partial hepatectomy and left lateral segmentectomy: technique and results of a clinical series. Surgery. 1996;120:468–75.CrossRefPubMed Kaneko H, Takagi S, Shiba T. Laparoscopic partial hepatectomy and left lateral segmentectomy: technique and results of a clinical series. Surgery. 1996;120:468–75.CrossRefPubMed
3.
go back to reference Koffron AJ, Kung R, Baker T, Fryer J, Clark L, Abecassis M. Laparoscopic-assisted right lobe donor hepatectomy. Am J Transplant. 2006;6:2522–5.CrossRefPubMed Koffron AJ, Kung R, Baker T, Fryer J, Clark L, Abecassis M. Laparoscopic-assisted right lobe donor hepatectomy. Am J Transplant. 2006;6:2522–5.CrossRefPubMed
4.
go back to reference Otsuka Y, Tsuchiya M, Katagiri T, Maeda T, Suzuki T, Kubota Y, et al. Hepatic parenchymal transection in laparoscopic hepatectomy for hepatocellular carcinoma with liver cirrhosis: selection and technique of surgical devices. J Microw Surg. 2006;24:73–7.CrossRef Otsuka Y, Tsuchiya M, Katagiri T, Maeda T, Suzuki T, Kubota Y, et al. Hepatic parenchymal transection in laparoscopic hepatectomy for hepatocellular carcinoma with liver cirrhosis: selection and technique of surgical devices. J Microw Surg. 2006;24:73–7.CrossRef
5.
go back to reference Takagi S. Hepatic and portal vein blood flow during carbon dioxide pneumoperitoneum for laparoscopic hepatectomy. Surg Endosc. 1998;12:427–31.CrossRefPubMed Takagi S. Hepatic and portal vein blood flow during carbon dioxide pneumoperitoneum for laparoscopic hepatectomy. Surg Endosc. 1998;12:427–31.CrossRefPubMed
6.
go back to reference Min SK, Kim JH, Lee SY. Carbon dioxide and argon gas embolism during laparoscopic hepatic resection. Acta Anaesthesiol Scand. 2007;51:949–53.CrossRefPubMed Min SK, Kim JH, Lee SY. Carbon dioxide and argon gas embolism during laparoscopic hepatic resection. Acta Anaesthesiol Scand. 2007;51:949–53.CrossRefPubMed
7.
go back to reference Curley SA, Izzo F, Ellis LM, Nicolas Vauthey J, Vallone P. Radiofrequency ablation of hepatocellular cancer in 110 patients with cirrhosis. Ann Surg. 2000;232:381–91.CrossRefPubMed Curley SA, Izzo F, Ellis LM, Nicolas Vauthey J, Vallone P. Radiofrequency ablation of hepatocellular cancer in 110 patients with cirrhosis. Ann Surg. 2000;232:381–91.CrossRefPubMed
8.
go back to reference Llovet JM, Vilana R, Brú C, Bianchi L, Salmeron JM, Boix L, et al. Increased risk of tumor seeding after percutaneous radiofrequency ablation for single hepatocellular carcinoma. Hepatology. 2001;33:1124–9.CrossRefPubMed Llovet JM, Vilana R, Brú C, Bianchi L, Salmeron JM, Boix L, et al. Increased risk of tumor seeding after percutaneous radiofrequency ablation for single hepatocellular carcinoma. Hepatology. 2001;33:1124–9.CrossRefPubMed
9.
go back to reference Teratani T, Yoshida H, Shiina S, Obi S, Sato S, Tateishi R, et al. Radiofrequency ablation for hepatocellular carcinoma in so-called high-risk locations. Hepatology. 2006;43:1101–8.CrossRefPubMed Teratani T, Yoshida H, Shiina S, Obi S, Sato S, Tateishi R, et al. Radiofrequency ablation for hepatocellular carcinoma in so-called high-risk locations. Hepatology. 2006;43:1101–8.CrossRefPubMed
10.
go back to reference Cherqui D, Laurent A, Tayar C, Chang S, Van Nhieu JT, Loriau J, et al. Laparoscopic liver resection for peripheral hepatocellular carcinoma in patients with chronic liver disease: midterm results and perspectives. Ann Surg. 2006;243:499–506.CrossRefPubMed Cherqui D, Laurent A, Tayar C, Chang S, Van Nhieu JT, Loriau J, et al. Laparoscopic liver resection for peripheral hepatocellular carcinoma in patients with chronic liver disease: midterm results and perspectives. Ann Surg. 2006;243:499–506.CrossRefPubMed
11.
go back to reference Haga Y, Ikei S, Wada Y, Takeuchi H, Sameshima H, Kimura O, et al. Evaluation of an Estimation of Physiologic Ability and Surgical Stress (E-PASS) scoring system to predict postoperative risk: a multicenter prospective study. Surg Today. 2001;31:569–74.CrossRefPubMed Haga Y, Ikei S, Wada Y, Takeuchi H, Sameshima H, Kimura O, et al. Evaluation of an Estimation of Physiologic Ability and Surgical Stress (E-PASS) scoring system to predict postoperative risk: a multicenter prospective study. Surg Today. 2001;31:569–74.CrossRefPubMed
12.
go back to reference Kaneko H, Takagi S, Otsuka Y, Tsuchiya M, Tamura A, Katagiri T, et al. Laparoscopic liver resection of hepatocellular carcinoma. Am J Surg. 2005;189:190–4.CrossRefPubMed Kaneko H, Takagi S, Otsuka Y, Tsuchiya M, Tamura A, Katagiri T, et al. Laparoscopic liver resection of hepatocellular carcinoma. Am J Surg. 2005;189:190–4.CrossRefPubMed
13.
go back to reference Simillis C, Constantinides VA, Tekkis PP, Darzi A, Lovegrove R, Jiao L, et al. Laparoscopic versus open hepatic resections for benign and malignant neoplasms—a meta-analysis. Surgery. 2007;141:203–11.CrossRefPubMed Simillis C, Constantinides VA, Tekkis PP, Darzi A, Lovegrove R, Jiao L, et al. Laparoscopic versus open hepatic resections for benign and malignant neoplasms—a meta-analysis. Surgery. 2007;141:203–11.CrossRefPubMed
14.
go back to reference Tanaka A, Takeda R, Mukaihara S, Hayakawa K, Shibata T, Itoh K, et al. Treatment of ruptured hepatocellular carcinoma. Int J Clin Oncol. 2001;6:291–5.CrossRefPubMed Tanaka A, Takeda R, Mukaihara S, Hayakawa K, Shibata T, Itoh K, et al. Treatment of ruptured hepatocellular carcinoma. Int J Clin Oncol. 2001;6:291–5.CrossRefPubMed
15.
go back to reference Rees M, Tekkis PP, Welsh FK, O’Rourke T, John TG. Evaluation of long-term survival after hepatic resection for metastatic colorectal cancer: a multifactorial model of 929 patients. Ann Surg. 2008;247:125–35.CrossRefPubMed Rees M, Tekkis PP, Welsh FK, O’Rourke T, John TG. Evaluation of long-term survival after hepatic resection for metastatic colorectal cancer: a multifactorial model of 929 patients. Ann Surg. 2008;247:125–35.CrossRefPubMed
16.
go back to reference Adam R, Delvart V, Pascal G, Valeanu A, Castaing D, Azoulay D, et al. Rescue surgery for unresectable colorectal liver metastases downstaged by chemotherapy: a model to predict long-term survival. Ann Surg. 2004;240:644–57.CrossRefPubMed Adam R, Delvart V, Pascal G, Valeanu A, Castaing D, Azoulay D, et al. Rescue surgery for unresectable colorectal liver metastases downstaged by chemotherapy: a model to predict long-term survival. Ann Surg. 2004;240:644–57.CrossRefPubMed
17.
go back to reference Poon RT, Fan ST, Lo CM, Liu CL, Ngan H, Ng IO, et al. Hepatocellular carcinoma in the elderly: results of surgical and nonsurgical management. Am J Gastroenterol. 1999;94:2460–6.CrossRefPubMed Poon RT, Fan ST, Lo CM, Liu CL, Ngan H, Ng IO, et al. Hepatocellular carcinoma in the elderly: results of surgical and nonsurgical management. Am J Gastroenterol. 1999;94:2460–6.CrossRefPubMed
18.
go back to reference Hanazaki K, Kajikawa S, Shimozawa N, Shimada K, Hiraguri M, Koide N, et al. Hepatic resection for hepatocellular carcinoma in the elderly. J Am Coll Surg. 2001;192:38–46.CrossRefPubMed Hanazaki K, Kajikawa S, Shimozawa N, Shimada K, Hiraguri M, Koide N, et al. Hepatic resection for hepatocellular carcinoma in the elderly. J Am Coll Surg. 2001;192:38–46.CrossRefPubMed
19.
go back to reference Delgado S, Lacy AM, García Valdecasas JC, Balagué C, Pera M, Salvador L, et al. Could age be an indication for laparoscopic colectomy in colorectal cancer? Surg Endosc. 2000;14:22–6.CrossRefPubMed Delgado S, Lacy AM, García Valdecasas JC, Balagué C, Pera M, Salvador L, et al. Could age be an indication for laparoscopic colectomy in colorectal cancer? Surg Endosc. 2000;14:22–6.CrossRefPubMed
20.
go back to reference Senagore AJ, Madbouly KM, Fazio VW, Duepree HJ, Brady KM, Delaney CP. Advantages of laparoscopic colectomy in older patients. Arch Surg. 2003;138:252–6.CrossRefPubMed Senagore AJ, Madbouly KM, Fazio VW, Duepree HJ, Brady KM, Delaney CP. Advantages of laparoscopic colectomy in older patients. Arch Surg. 2003;138:252–6.CrossRefPubMed
21.
go back to reference Kaneko H, Tsuchiya M, Otsuka Y, Tamura A, Katagiri T, Maeda T, et al. Laparoscopy-assisted Hepatectomy for Giant Hepatocellular Carcinoma. Surg Laparosc Endosc Percutan Tech. 2008;18:127–31.CrossRef Kaneko H, Tsuchiya M, Otsuka Y, Tamura A, Katagiri T, Maeda T, et al. Laparoscopy-assisted Hepatectomy for Giant Hepatocellular Carcinoma. Surg Laparosc Endosc Percutan Tech. 2008;18:127–31.CrossRef
22.
go back to reference Cho JY, Han HS, Yoon YS, Shin SH. Feasibility of laparoscopic liver resection for tumors located in the posterosuperior segments of the liver, with a special reference to overcoming current limitations on tumor location. Surgery. 2008;144:32–8.CrossRefPubMed Cho JY, Han HS, Yoon YS, Shin SH. Feasibility of laparoscopic liver resection for tumors located in the posterosuperior segments of the liver, with a special reference to overcoming current limitations on tumor location. Surgery. 2008;144:32–8.CrossRefPubMed
Metadata
Title
Laparoscopic hepatectomy for liver tumors: proposals for standardization
Authors
Yuichiro Otsuka
Masaru Tsuchiya
Tetsuya Maeda
Toshio Katagiri
Jun Isii
Akira Tamura
Kunihiro Yamazaki
Yoshihisa Kubota
Takashi Suzuki
Takayuki Suzuki
Satoru Kagami
Hironori Kaneko
Publication date
01-11-2009
Publisher
Springer Japan
Published in
Journal of Hepato-Biliary-Pancreatic Sciences / Issue 6/2009
Print ISSN: 1868-6974
Electronic ISSN: 1868-6982
DOI
https://doi.org/10.1007/s00534-009-0139-x

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