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Surgical Endoscopy

Published in:

01-11-2012

Laparoscopic approach for treatment of multiple hepatocellular carcinomas

Authors: Yoo-Seok Yoon, Ho-Seong Han, Jai Young Cho, Chang Jin Yoon, Ji Hoon Kim

Published in: Surgical Endoscopy | Issue 11/2012

Abstract

Background

The aim of this study is to evaluate clinical and oncologic outcomes after laparoscopic surgery for patients with multiple hepatocellular carcinoma (HCC).

Methods

Among the 260 patients who underwent laparoscopic procedures, including laparoscopic liver resection and laparoscopic radiofrequency ablation (LRFA), between September 2003 and December 2009, 107 patients with HCC were included in this retrospective study. According to tumor multiplicity, patients were divided into multiple lesion (n = 23) and single lesion (n = 84) groups. We compared the operative outcomes after the laparoscopic procedures between the single and multiple tumor groups.

Results

There was no difference in the clinicopathologic characteristics between the two groups, except the multiple group had more frequent previous history of preoperative transarterial chemoembolization. LRFA was more frequently used in the multiple group as compared with the single group. There was no postoperative mortality in either group. Application of laparoscopic surgery in the multiple group did not increase the operative time, rate of intraoperative transfusion, length of postoperative hospital stay, or postoperative complications, as compared with the single group. After median follow-up of 33.7 months, there was no statistically significant difference of the survival rates between the two groups, although there was a better disease-free survival rate in the single group.

Conclusions

This study shows that laparoscopic surgery, including LH and LRFA, can be safely applied to patients with multiple HCCs, and the survival outcomes are acceptable.

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Title: Laparoscopic approach for treatment of multiple hepatocellular carcinomas
Authors: Yoo-Seok Yoon
Ho-Seong Han
Jai Young Cho
Chang Jin Yoon
Ji Hoon Kim
Publication date: 01-11-2012
Publisher: Springer-Verlag
Published in: Surgical Endoscopy / Issue 11/2012
Print ISSN: 0930-2794
Electronic ISSN: 1432-2218
DOI: https://doi.org/10.1007/s00464-012-2304-6

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Laparoscopic approach for treatment of multiple hepatocellular carcinomas

Abstract

Background

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Methods

Results

Conclusions

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