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01-08-2012 | Case Report

Langerhans’ cell histiocytosis in the pediatric spine: therapeutic dynamic change of spinal deformity

Authors: Yi-Chieh Hung, Feng-Chi Chang, Yi-Wei Chen, Mul-Li Liang, Hsin-Hung Chen, Sanford P. C. Hsu, Huai-che Yang, Tai-Tong Wong

Published in: Child's Nervous System | Issue 8/2012

Excerpt

Langerhans’ cell histiocytosis (LCH) is a kind of neoplasm caused by a proliferation of Langerhans’ cells within the tissue. LCH can be classified as a unifocal unisystem (also known as eosinophilic granulation), multifocal unisystem (Hand–Schuller–Christian disease), or multifocal multisystem (Letterer–Siwe disease), based on the area of invasion. Unifocal unisystem disease is the most common and usually presents with a single lytic bone lesion. The incidence of spinal lesion was about 12.5–35 % [5, 15, 23] in all cases of LCH. …

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Title: Langerhans’ cell histiocytosis in the pediatric spine: therapeutic dynamic change of spinal deformity
Authors: Yi-Chieh Hung
Feng-Chi Chang
Yi-Wei Chen
Mul-Li Liang
Hsin-Hung Chen
Sanford P. C. Hsu
Huai-che Yang
Tai-Tong Wong
Publication date: 01-08-2012
Publisher: Springer-Verlag
Published in: Child's Nervous System / Issue 8/2012
Print ISSN: 0256-7040
Electronic ISSN: 1433-0350
DOI: https://doi.org/10.1007/s00381-012-1764-2

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Langerhans’ cell histiocytosis in the pediatric spine: therapeutic dynamic change of spinal deformity

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