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Indian Journal of Pediatrics
Published in: Indian Journal of Pediatrics 9/2014

01-09-2014 | Pediatrics in General Practice

Lactose Intolerance and Other Disaccharidase Deficiency

Author: Balvir S. Tomar

Published in: Indian Journal of Pediatrics | Issue 9/2014

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Abstract

Intolerance to foods which contain lactose can cause a range of intestinal and systemic symptoms. These symptoms are caused by Lactase deficiency which is encoded by a single gene (LCT) of ≈ 50 kb located on chromosome 2q21. In some food items, lactose has been missed because of “hidden” lactose due to inadequately labeled, confusing diagnosis of lactose intolerance based on dietary restriction of dairy foods. Two polymorphisms, C/T13910 and G/A22018, linked to hypolactasia, correlate with breath hydrogen and symptoms after lactose. The key in the management of lactose intolerance is the dietary removal of lactose. Patients diagnosed as lactose intolerant must be advised of “risk” foods, inadequately labeled, including processed meats, bread, cake mixes, soft drinks, and lagers. This review highlights the types, symptoms and management of lactose intolerance and also highlights differences from milk allergy which closely mimics the symptoms of lactose intolerance.
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Metadata
Title
Lactose Intolerance and Other Disaccharidase Deficiency
Author
Balvir S. Tomar
Publication date
01-09-2014
Publisher
Springer India
Published in
Indian Journal of Pediatrics / Issue 9/2014
Print ISSN: 0019-5456
Electronic ISSN: 0973-7693
DOI
https://doi.org/10.1007/s12098-014-1346-2

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