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BMC Women's Health
Published in: BMC Women's Health 1/2018

Open Access 01-12-2018 | Research article

Knowledge of HPV and acceptability of HPV vaccine among women in western China: a cross-sectional survey

Authors: Junyong He, Lixia He

Published in: BMC Women's Health | Issue 1/2018

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Abstract

Background

Since most cervical cancer cases are caused by persistent high-risk human papillomavirus (HR-HPV) infection, knowledge of HPV among women is essential for the prevent of cervical cancer. This study was aimed to assess knowledge among women in western China about HPV and its association with cervical cancer, and to assess their acceptance of HPV vaccination.

Methods

A sample of healthy women undergoing routine physical examinations in the Health Management Center of West China Hospital, Sichuan University between January and December 2014 completed a questionnaire.

Results

A total of 1300 questionnaires were distributed, and 1109 were completed and analyzed. Only 28.85% of respondents (n = 320) had heard of HPV; among this subgroup, only half (53.44%) knew that it causes cervical cancer, only 26 (8.13%) correctly answered all questions about HPV. Multivariate analysis showed that respondents who had heard of HPV were more likely than other respondents to have a family history of any cancer, to undergo regular Pap tests and to have completed at least secondary education. Half of all respondents (51.22%) reported that they would be willing to be vaccinated against HPV.

Conclusion

Although most women in western China lack basic knowledge about HPV, at least half are willing to take the HPV vaccine. Public health efforts to educate the public about HPV and its connection to cervical cancer should be strengthened and expanded.
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Literature
1.
Ferlay J, Soerjomataram I, Dikshit R, Eser S, Mathers C, Rebelo M, et al. Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012. Int J Cancer. 2015;136:e359–86.CrossRefPubMed
2.
3.
Muñoz N, Bosch FX, de Sanjosé S, Tafur L, Izarzugaza I, Gili M, et al. The causal link between human papillomavirus and invasive cervical cancer: a population-based case–control study in Colombia and Spain. Int J Cancer. 1992;52:743–9.CrossRefPubMed
4.
Schiffman MH, Bauer HM, Hoover RN, Glass AG, Cadell DM, Rush BB, et al. Epidemiologic evidence showing that human papillomavirus infection causes most cervical intraepithelial neoplasia. J Natl Cancer Inst. 1993;85:958–64.CrossRefPubMed
5.
Walboomers JM, Jacobs MV, Manos MM, Bosch FX, Kummer JA, Shah KV, et al. Human papillomavirus is a necessary cause of invasive cervical cancer worldwide. J Pathol. 1999;189:12–9.CrossRefPubMed
6.
7.
Sawaya GF, Kulasingam S, Denberg TD, Qaseem A. Clinical guidelines Committee of the American College of physicians. Cervical cancer screening in average-risk women: best practice advice from the clinical guidelines Committee of the American College of physicians. Ann Intern Med. 2015;162(12):851–9.CrossRefPubMed
8.
FUTURE II Study Group. Quadrivalent vaccine against human papillomavirus to prevent high-grade cervical lesions. N Engl J Med. 2007;356(19):1915–27.CrossRef
9.
Paavonen J, Naud P, Salmerón J, Wheeler CM, Chow SN, Apter D, et al. Efficacy of human papillomavirus (HPV)-16/18 AS04-adjuvanted vaccine against cervical infection and precancer caused by oncogenic HPV types (PATRICIA): final analysis of a double-blind, randomised study in young women. Lancet. 2009;374(9686):301–14.CrossRefPubMed
10.
Hu S-Y, Qiao Y-L. Unscramble to World Health Organization position paper on vaccines against HPV published in 2017. Zhonghua Yu Fang Yi Xue Za Zhi. 2018;52:464–8.PubMed
11.
Zhang S-K, Pan X-F, Wang S-M, Yang C-X, Gao X-H, Wang Z-Z, et al. Perceptions and acceptability of HPV vaccination among parents of young adolescents: a multicenter national survey in China. Vaccine. 2013;31:3244–9.CrossRefPubMed
12.
Klug SJ, Hukelmann M, Blettner M. Knowledge about infection with human papillomavirus: a systematic review. Prev Med. 2008;46:87–98.CrossRefPubMed
13.
Zhao F-H, Tiggelaar SM, Hu S-Y, Zhao N, Hong Y, Niyazi M, et al. A multi-center survey of HPV knowledge and attitudes toward HPV vaccine among women, government officials, and medical personnel in China. Asian Pac J Cancer Prev. 2012;13(5):2369–78.CrossRefPubMedPubMedCentral
14.
Wang W, Ma Y-Y, Wang X, Zou H-C, Zhao F-H, Wang S-M, et al. Acceptability of human papillomavirus vaccine among parents of junior middle school students in jinan, China. Vaccine. 2015;33:2570–6.CrossRefPubMed
15.
Tang S-Y, Liu Z-H, Li L, Cai H-L, Wan Y-P. Awareness and knowledge about human papillomavirus among high school students in China. J Reprod Med. 2014;59(1–2):44–50.PubMed
16.
Xue L, Hu W-Q, Zhang H-M, Xie Z-L, Zhang X, Zhao F-H, et al. Awareness of and willingness to be vaccinated by human papillomavirus vaccine among junior middle school students in Jinan, China. Hum Vaccine Immunother. 2018;14:404–11.CrossRef
17.
Stefanie J, Klug MH, Blettner M. Knowledge about infection with human papillomavirus: a systematic review. Prev Med. 2008;46:87–98.CrossRef
18.
Tiro HIM JA, Kobrin S, Chollette V. What do women in the U.S. know about human papillomavirus and cervical Cancer? Cancer Epidemiol Biomark Prev. 2007;16:288–94.CrossRef
19.
Marlow LA, Zimet GD, McCaffery KJ, Ostini R, Waller J. Knowledge of human papillomavirus (HPV) and HPV vaccine: an international comparison. Vaccine. 2012;31:763–9.CrossRefPubMed
20.
Gunasekaran B, Jayasinghe Y, Fenner Y, Moore EE, Wark JD, Fletcher A, et al. Knowledge of human papillomavirus and cervical cancer among young women recruited using a social networking site. Sex Transm Infect. 2012;89:327–9.CrossRefPubMed
21.
Makwe CC, Anorlu RI, Odeyemi KA. Human papillomavirus (HPV) infection and vaccines: knowledge, attitude and perception among female students at the University of Lagos, Lagos. Nigeria J Epidemiol Glob Health. 2013;2:199–206.CrossRef
22.
Marek E, Dergez T, Rebek-Nagy G, Szilard I, Kiss I, Ember I, et al. Effect of an educational intervention on Hungarian adolescents’ awareness, beliefs and attitudes on the prevention of cervical cancer. Vaccine. 2012;30:6824–32.CrossRefPubMed
23.
Kester LM, Shedd-Steele RB, Dotson-Roberts CA, Smith J, Zimet GD. The effects of a brief educational intervention on human papillomavirus knowledge and intention to initiate HPV vaccine in 18-26 year old young adults. Gynecol Oncol. 2014;132(Suppl 1):S9–12.CrossRefPubMed
24.
McCarey C, Pirek D, Tebeu PM, Boulvain M, Doh AS, Petignat P. Awareness of HPV and cervical cancer prevention among Cameroonian healthcare workers. BMC Womens Health. 2011;11:45.CrossRefPubMedPubMedCentral
25.
Kwan TT, Lo SS, Tam KF, Chan KK, Ngan HY. Assessment of knowledge and stigmatizing attitudes related to human papillomavirus among Hong Kong Chinese healthcare providers. Int J Gynaecol Obstet. 2012;116:52–6.CrossRefPubMed
26.
Ndizeye Z, Vanden Broeck D, Vermandere H, Bogers JP, Van Geertruyden JP. Knowledge and practices of general practitioners at district hospitals towards cervical cancer prevention in Burundi, 2015: a cross-sectional study. Glob Health. 2018;14:4.CrossRef
27.
Chang Irene J, Huang R, He W, Zhang S-K, Wang S-M, Zhao F-H, et al. Effect of an educational intervention on HPV knowledge and vaccine attitudes among urban employed women and female undergraduate students in China: a cross-sectional study. BMC Public Health. 2013;13(1):916.CrossRefPubMedPubMedCentral
28.
Hoque ME, Ghuman S, Hal GV. Human papillomavirus vaccine acceptability among female university students in South Africa. Asian Pac J Cancer Prev. 2013;14:4865–9.CrossRefPubMed
29.
Remes P, Selestine V, Changalucha J, Ross DA, Wight D, de Sanjosé S. A qualitative study of HPV vaccine acceptability among health workers, teachers, parents, female pupils, and religious leaders in Northwest Tanzania. Vaccine. 2012;30:5363–7.CrossRefPubMedPubMedCentral
30.
Juraskova I, Bari RA, O'Brien MT, KJ MC. HPV vaccine promotion: does referring to both cervical cancer and genital warts affect intended and actual vaccine behavior? Womens Health Issues. 2010;21:71–9.CrossRef
31.
Iliyasu Z, Abubakar IS, Aliyu MH, Galadanci HS. Cervical cancer risk perception and predictors of human papilloma virus vaccine acceptability among female university students in northern Nigeria. J Obstet Gynaecol. 2010;30:857–62.CrossRefPubMed
32.
Warnecke RB, Johnson TP, Chávez N, Sudman S, O'Rourke DP, Lacey L, et al. Improving question wording in surveys of culturally diverse populations. Ann Epidemiol. 1997;7:334–42.CrossRefPubMed
33.
Brener NDGJ, Kann L, McManus T, Ross J. Assessing health risk behaviors among adolescents: the effect of question wording and appeals for honesty. J Adolesc Health. 2004;35:91–100.CrossRefPubMed
34.
Gelman A, Nikolajski C, Schwarz EB, Borrero S. Racial disparities in awareness of the human papillomavirus. J Women's Health (Larchmt). 2011;20:1165–73.CrossRef
Metadata
Title
Knowledge of HPV and acceptability of HPV vaccine among women in western China: a cross-sectional survey
Authors
Junyong He
Lixia He
Publication date
01-12-2018
Publisher
BioMed Central
Published in
BMC Women's Health / Issue 1/2018
Electronic ISSN: 1472-6874
DOI
https://doi.org/10.1186/s12905-018-0619-8

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