Skip to main content
Top
Published in: Systematic Reviews 1/2014

Open Access 01-12-2014 | Protocol

Knowledge, attitudes and practices on adolescent vaccination among parents, teachers and adolescents in Africa: a systematic review protocol

Authors: Leila H Abdullahi, Benjamin M Kagina, Tali Cassidy, Esther F Adebayo, Charles S Wiysonge, Gregory D Hussey

Published in: Systematic Reviews | Issue 1/2014

Login to get access

Abstract

Background

Vaccines are the most successful and cost-effective public health interventions available to avert vaccine-preventable diseases and deaths. Despite progress in the field of adolescent health, many young people in Africa still get sick and die from vaccine-preventable diseases due to lack of vaccination. Parents, adolescents and teachers are key players with regard to implementation of adolescent vaccination policies. Therefore, understanding their knowledge, attitudes and practices towards adolescent vaccination may provide clues on what can be done to improve vaccine uptake among adolescents. The aim of this study is to conduct a qualitative and quantitative systematic review on knowledge, attitudes and practices on adolescent vaccination among parents, teachers and adolescents in Africa.

Methods

We will include both quantitative and qualitative primary studies. Eligible quantitative studies include both intervention and observational studies. Qualitative studies to be included are focus group discussions, direct observations, in-depth interviews and case ethnographic studies. We will search PubMed, Cochrane Central Register of Controlled Trials, Scopus, Web of Science, WHOLIS, Africa Wide and CINAHL for eligible studies with no time and language limits. We will also check reference lists of included studies for other eligible reports. Two authors will independently screen the search output, select studies and extract data, resolving discrepancies by consensus and discussion. We will analyse qualitative data using thematic analysis where applicable, and quantitative studies findings will be presented in a narrative synthesis form based on the outcomes.

Discussion

The findings from this systematic review will guide the identification of gaps on knowledge, attitudes and practices among the key role players on adolescent vaccination. We anticipate that our findings will guide the development of adolescent-focused vaccination policy in Africa, which is virtually non-existent at present.

Systematic review registration

This review is registered with PROSPERO, registration number CRD42014010395.
Appendix
Available only for authorised users
Literature
1.
go back to reference World Health Organization, United Nations Children’s Fund: State of the World’s Vaccines and Immunization. 2009, Geneva: World Health Organization, 3 World Health Organization, United Nations Children’s Fund: State of the World’s Vaccines and Immunization. 2009, Geneva: World Health Organization, 3
2.
go back to reference Andre FE, Booy R, Bock HL, Clemens J, Datta SK, John TJ, Lee BW, Lolekha S, Peltola H, Ruff TA, Santosham M, Schmitt MHJ: Vaccination greatly reduces disease, disability, death and inequity worldwide. Bull World Health Organ. 2008, 86: 140-146. 10.2471/BLT.07.040089.CrossRefPubMed Andre FE, Booy R, Bock HL, Clemens J, Datta SK, John TJ, Lee BW, Lolekha S, Peltola H, Ruff TA, Santosham M, Schmitt MHJ: Vaccination greatly reduces disease, disability, death and inequity worldwide. Bull World Health Organ. 2008, 86: 140-146. 10.2471/BLT.07.040089.CrossRefPubMed
3.
go back to reference Mackroth M, Irwin K, Vandelaer J, Hombach J, Eckert L: Immunizing school-age children and adolescents: experience from low- and middle-income countries. Vaccine. 2010, 28: 1138-1147. 10.1016/j.vaccine.2009.11.008.CrossRefPubMed Mackroth M, Irwin K, Vandelaer J, Hombach J, Eckert L: Immunizing school-age children and adolescents: experience from low- and middle-income countries. Vaccine. 2010, 28: 1138-1147. 10.1016/j.vaccine.2009.11.008.CrossRefPubMed
4.
go back to reference Zipursky S, Wiysonge CS, Hussey G: Knowledge and attitudes towards vaccines and immunization among adolescents in South Africa. Hum Vaccin. 2010, 6: 455-461. 10.4161/hv.6.6.11660.CrossRefPubMed Zipursky S, Wiysonge CS, Hussey G: Knowledge and attitudes towards vaccines and immunization among adolescents in South Africa. Hum Vaccin. 2010, 6: 455-461. 10.4161/hv.6.6.11660.CrossRefPubMed
5.
go back to reference Lee G, LeBaron C, Murphy T, Lett S, Schauer S, Lieu T: Pertussis in adolescents and adults: should we vaccinate?. Pediatrics. 2005, 115: 1675-10.1542/peds.2004-2509.CrossRefPubMed Lee G, LeBaron C, Murphy T, Lett S, Schauer S, Lieu T: Pertussis in adolescents and adults: should we vaccinate?. Pediatrics. 2005, 115: 1675-10.1542/peds.2004-2509.CrossRefPubMed
6.
go back to reference Decade of vaccines collaboration, Global vaccine action plan. Vaccine. 2013, 31S: B5-B31. Decade of vaccines collaboration, Global vaccine action plan. Vaccine. 2013, 31S: B5-B31.
8.
go back to reference Ayissi CA, Wamai RG, Oduwo GO, Perlman S, Welty E, Welty T, Manga S, Ogembo JG: Awareness, acceptability and uptake of human papilloma virus vaccine among Cameroonian school-attending female adolescents. J Commun Health. 2012, 37: 1127-1135. 10.1007/s10900-012-9554-z.CrossRef Ayissi CA, Wamai RG, Oduwo GO, Perlman S, Welty E, Welty T, Manga S, Ogembo JG: Awareness, acceptability and uptake of human papilloma virus vaccine among Cameroonian school-attending female adolescents. J Commun Health. 2012, 37: 1127-1135. 10.1007/s10900-012-9554-z.CrossRef
9.
go back to reference Binagwaho A, Wagner CM, Gatera M, Karema C, Nutt CT, Ngabo F: Achieving high coverage in Rwanda’s national human papillomavirus vaccination programme. Bull World Health Organ. 2012, 90: 623-628. 10.2471/BLT.11.097253.CrossRefPubMedPubMedCentral Binagwaho A, Wagner CM, Gatera M, Karema C, Nutt CT, Ngabo F: Achieving high coverage in Rwanda’s national human papillomavirus vaccination programme. Bull World Health Organ. 2012, 90: 623-628. 10.2471/BLT.11.097253.CrossRefPubMedPubMedCentral
10.
go back to reference Binagwaho A, Wagner CM, Nutt CT: HPV vaccine in Rwanda: different disease, same double standard. Lancet. 2011, 378: 1916-10.1016/S0140-6736(11)61837-0.CrossRefPubMed Binagwaho A, Wagner CM, Nutt CT: HPV vaccine in Rwanda: different disease, same double standard. Lancet. 2011, 378: 1916-10.1016/S0140-6736(11)61837-0.CrossRefPubMed
11.
go back to reference Ouedraogo N, Mu¨ller O, Jahn A, Gerhardus A: Human papillomavirus vaccination in Africa. Lancet. 2011, 378: 315-316.CrossRefPubMed Ouedraogo N, Mu¨ller O, Jahn A, Gerhardus A: Human papillomavirus vaccination in Africa. Lancet. 2011, 378: 315-316.CrossRefPubMed
12.
go back to reference La Montagne DS, Barge S, Le NT, Mugisha E, Penny ME, Gandhi S, Janmohamed A, Kumakech E, Mosqueira NR, Nguyen NQ, Paul P, Tang Y, Minh TH, Uttekar BP, Jumaan AO: Human papillomavirus vaccine delivery strategies that achieved high coverage in low-and middle-income countries. Bull World Health Organ. 2011, 89: 821-830. 10.2471/BLT.11.08986.CrossRef La Montagne DS, Barge S, Le NT, Mugisha E, Penny ME, Gandhi S, Janmohamed A, Kumakech E, Mosqueira NR, Nguyen NQ, Paul P, Tang Y, Minh TH, Uttekar BP, Jumaan AO: Human papillomavirus vaccine delivery strategies that achieved high coverage in low-and middle-income countries. Bull World Health Organ. 2011, 89: 821-830. 10.2471/BLT.11.08986.CrossRef
13.
go back to reference Watson-Jones D, Baisley K, Ponsiano R, Lemme F, Remes P, Ross D, Kapiga S, Mayaud P, De Sanjosé S, Wight D, Changalucha J, Hayes R: Human papillomavirus vaccination in Tanzanian schoolgirls: cluster-randomized trial comparing 2 vaccine-delivery strategies. J Infect Dis. 2012, 206: 678-686. 10.1093/infdis/jis407.CrossRefPubMedPubMedCentral Watson-Jones D, Baisley K, Ponsiano R, Lemme F, Remes P, Ross D, Kapiga S, Mayaud P, De Sanjosé S, Wight D, Changalucha J, Hayes R: Human papillomavirus vaccination in Tanzanian schoolgirls: cluster-randomized trial comparing 2 vaccine-delivery strategies. J Infect Dis. 2012, 206: 678-686. 10.1093/infdis/jis407.CrossRefPubMedPubMedCentral
14.
go back to reference Ladner J, Besson MH, Hampshire R, Tapert L, Chirenje M, Saba J: Assessment of eight HPV vaccination programs implemented in lowest income countries. BMC Public Health. 2012, 12: 370-10.1186/1471-2458-12-370.CrossRefPubMedPubMedCentral Ladner J, Besson MH, Hampshire R, Tapert L, Chirenje M, Saba J: Assessment of eight HPV vaccination programs implemented in lowest income countries. BMC Public Health. 2012, 12: 370-10.1186/1471-2458-12-370.CrossRefPubMedPubMedCentral
15.
go back to reference Moodley I, Tathiah N, Mubaiwa V, Denny L: High uptake of Gardasil vaccine among 9–12-year-old schoolgirls participating in an HPV vaccination demonstration project in KwaZulu-Natal, South Africa. S Afr Med J. 2013, 103: 313-317. Moodley I, Tathiah N, Mubaiwa V, Denny L: High uptake of Gardasil vaccine among 9–12-year-old schoolgirls participating in an HPV vaccination demonstration project in KwaZulu-Natal, South Africa. S Afr Med J. 2013, 103: 313-317.
16.
go back to reference Perlman S, Wamai RG, Bain PA, Welty T, Welty E, Ogembo JG: Knowledge and awareness of HPV vaccine and acceptability to vaccinate in sub-Saharan Africa: a systematic review. PLoS One. 2014, 9: e90912-10.1371/journal.pone.0090912.CrossRefPubMedPubMedCentral Perlman S, Wamai RG, Bain PA, Welty T, Welty E, Ogembo JG: Knowledge and awareness of HPV vaccine and acceptability to vaccinate in sub-Saharan Africa: a systematic review. PLoS One. 2014, 9: e90912-10.1371/journal.pone.0090912.CrossRefPubMedPubMedCentral
17.
go back to reference World Health Organization: Human Papillomavirus Vaccines. 2009, WHO Position Paper, 118-131. World Health Organization: Human Papillomavirus Vaccines. 2009, WHO Position Paper, 118-131.
20.
go back to reference Brabin L, Greenberg DP, Hessel L, Hyer R, Ivanoff B, Van Damme P: Current issues in adolescent immunization. Vaccine. 2008, 26: 4120-4134. 10.1016/j.vaccine.2008.04.055.CrossRefPubMed Brabin L, Greenberg DP, Hessel L, Hyer R, Ivanoff B, Van Damme P: Current issues in adolescent immunization. Vaccine. 2008, 26: 4120-4134. 10.1016/j.vaccine.2008.04.055.CrossRefPubMed
22.
go back to reference The Society for Adolescent Health and Medicine: Adolescent consent for vaccination: a position paper of the society for adolescent health and medicine. J Adolesc Health. 2013, 53: 550-553.CrossRef The Society for Adolescent Health and Medicine: Adolescent consent for vaccination: a position paper of the society for adolescent health and medicine. J Adolesc Health. 2013, 53: 550-553.CrossRef
23.
go back to reference Gowda C, Schaffer S, Dombkowski K, Dempsey A: Understanding attitudes toward adolescent vaccination and the decision-making dynamic among adolescents, parents and providers. BMC Public Health. 2012, 12: 509-10.1186/1471-2458-12-509.CrossRefPubMedPubMedCentral Gowda C, Schaffer S, Dombkowski K, Dempsey A: Understanding attitudes toward adolescent vaccination and the decision-making dynamic among adolescents, parents and providers. BMC Public Health. 2012, 12: 509-10.1186/1471-2458-12-509.CrossRefPubMedPubMedCentral
24.
go back to reference Briss PA, Rodewald LE, Hinman AR, Shefer AM, Strikas RA, Bernier RR, Carande-Kulis VG, Yusuf HR, Ndiaye SM, Williams SM: Reviews of evidence regarding interventions to improve vaccination coverage in children, adolescents, and adults. The task force on community preventive services. Am J Prev Med. 2000, 18: 97-140.CrossRefPubMed Briss PA, Rodewald LE, Hinman AR, Shefer AM, Strikas RA, Bernier RR, Carande-Kulis VG, Yusuf HR, Ndiaye SM, Williams SM: Reviews of evidence regarding interventions to improve vaccination coverage in children, adolescents, and adults. The task force on community preventive services. Am J Prev Med. 2000, 18: 97-140.CrossRefPubMed
25.
go back to reference Mahomed H, Shea J, Kafaar F, Hawkridge T, Hanekom WA, Hussey GD: Are adolescents ready for tuberculosis vaccine trials?. Vaccine. 2008, 26: 4725-4730. 10.1016/j.vaccine.2008.06.088.CrossRefPubMed Mahomed H, Shea J, Kafaar F, Hawkridge T, Hanekom WA, Hussey GD: Are adolescents ready for tuberculosis vaccine trials?. Vaccine. 2008, 26: 4725-4730. 10.1016/j.vaccine.2008.06.088.CrossRefPubMed
26.
go back to reference Katz IT, Nkala B, Dietrich J, Wallace M, Bekker LG, Pollenz K, Bogart LM, Wright AA, Tsai AC, Bangsberg DR, Gray GE: A qualitative analysis of factors influencing HPV vaccine uptake in Soweto, South Africa among adolescents and their caregivers. PLoS One. 2013, 8: e72094-10.1371/journal.pone.0072094.CrossRefPubMedPubMedCentral Katz IT, Nkala B, Dietrich J, Wallace M, Bekker LG, Pollenz K, Bogart LM, Wright AA, Tsai AC, Bangsberg DR, Gray GE: A qualitative analysis of factors influencing HPV vaccine uptake in Soweto, South Africa among adolescents and their caregivers. PLoS One. 2013, 8: e72094-10.1371/journal.pone.0072094.CrossRefPubMedPubMedCentral
27.
go back to reference Harries J, Moodley J, Barone MA, Mall S, Sinanovic E: Preparing for HPV vaccination in South Africa: key challenges and opinions. Vaccine. 2009, 27: 38-44. 10.1016/j.vaccine.2008.10.033.CrossRefPubMed Harries J, Moodley J, Barone MA, Mall S, Sinanovic E: Preparing for HPV vaccination in South Africa: key challenges and opinions. Vaccine. 2009, 27: 38-44. 10.1016/j.vaccine.2008.10.033.CrossRefPubMed
28.
go back to reference Francis SA, Battle-Fisher M, Liverpool J, Hipple L, Mosavel M, Soogun S, Mofammere N: A qualitative analysis of South African women's knowledge, attitudes, and beliefs about HPV and cervical cancer prevention, vaccine awareness and acceptance, and maternal-child communication about sexual health. Vaccine. 2011, 29: 8760-8765. 10.1016/j.vaccine.2011.07.116.CrossRefPubMed Francis SA, Battle-Fisher M, Liverpool J, Hipple L, Mosavel M, Soogun S, Mofammere N: A qualitative analysis of South African women's knowledge, attitudes, and beliefs about HPV and cervical cancer prevention, vaccine awareness and acceptance, and maternal-child communication about sexual health. Vaccine. 2011, 29: 8760-8765. 10.1016/j.vaccine.2011.07.116.CrossRefPubMed
29.
go back to reference Gowda C, Carlos RC, Butchart AT, Singer DC, Davis MM, Clark SJ, Dempsey AF: CHIAS: a standardized measure of parental HPV immunization attitudes and beliefs and its associations with vaccine uptake. Sex Transm Dis. 2012, 39: 475-481. 10.1097/OLQ.0b013e318248a6d5.CrossRefPubMed Gowda C, Carlos RC, Butchart AT, Singer DC, Davis MM, Clark SJ, Dempsey AF: CHIAS: a standardized measure of parental HPV immunization attitudes and beliefs and its associations with vaccine uptake. Sex Transm Dis. 2012, 39: 475-481. 10.1097/OLQ.0b013e318248a6d5.CrossRefPubMed
30.
go back to reference Harris KM, Martin LT, Nicole L: Strategies and Models for Promoting Adolescent Vaccination for Low-Income Populations. 2009, Www Rand Org Harris KM, Martin LT, Nicole L: Strategies and Models for Promoting Adolescent Vaccination for Low-Income Populations. 2009, Www Rand Org
32.
go back to reference Barry D: Increasing Knowledge about HPV and the HPV Vaccine amongst Adolescents and Adults through a School-Based Setting: A Capstone Project. 2013 Barry D: Increasing Knowledge about HPV and the HPV Vaccine amongst Adolescents and Adults through a School-Based Setting: A Capstone Project. 2013
34.
go back to reference Kaliyaperumal K: Guideline for conducting a knowledge, attitude and practice (KAP) study. Commun Ophthalmol. 2004, 4: 7-9. Kaliyaperumal K: Guideline for conducting a knowledge, attitude and practice (KAP) study. Commun Ophthalmol. 2004, 4: 7-9.
37.
go back to reference JPT H: Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0. Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0. JPT H: Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0. Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0.
38.
go back to reference Goldsmith MR, Bankhead CR, Austoker J: Synthesising qualitative and quantitative research in evidence-based patient information. J Epidemiol Commun Health. 2007, 61: 262-270. 10.1136/jech.2006.046110.CrossRef Goldsmith MR, Bankhead CR, Austoker J: Synthesising qualitative and quantitative research in evidence-based patient information. J Epidemiol Commun Health. 2007, 61: 262-270. 10.1136/jech.2006.046110.CrossRef
39.
go back to reference Whiting L: Systematic review protocols: an introduction: Lisa S Whiting looks at the steps necessary to create a review protocol for appraising literature. Nurs Res. 2009, 17: 34-43. 10.7748/nr2009.10.17.1.34.c7337.CrossRef Whiting L: Systematic review protocols: an introduction: Lisa S Whiting looks at the steps necessary to create a review protocol for appraising literature. Nurs Res. 2009, 17: 34-43. 10.7748/nr2009.10.17.1.34.c7337.CrossRef
40.
go back to reference Bowers D, House A, Owens D: Carrying out a Systematic Search. Getting Started in Health Research. 2011, John Wiley & SonsCrossRef Bowers D, House A, Owens D: Carrying out a Systematic Search. Getting Started in Health Research. 2011, John Wiley & SonsCrossRef
41.
go back to reference Bearman M, Dawson P: Qualitative synthesis and systematic review in health professions education. Med Educ. 2013, 47: 252-260. 10.1111/medu.12092.CrossRefPubMed Bearman M, Dawson P: Qualitative synthesis and systematic review in health professions education. Med Educ. 2013, 47: 252-260. 10.1111/medu.12092.CrossRefPubMed
Metadata
Title
Knowledge, attitudes and practices on adolescent vaccination among parents, teachers and adolescents in Africa: a systematic review protocol
Authors
Leila H Abdullahi
Benjamin M Kagina
Tali Cassidy
Esther F Adebayo
Charles S Wiysonge
Gregory D Hussey
Publication date
01-12-2014
Publisher
BioMed Central
Published in
Systematic Reviews / Issue 1/2014
Electronic ISSN: 2046-4053
DOI
https://doi.org/10.1186/2046-4053-3-100

Other articles of this Issue 1/2014

Systematic Reviews 1/2014 Go to the issue