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Knee Surgery, Sports Traumatology, Arthroscopy

Published in:

01-09-2020 | Knee-TEP | KNEE

No effect of vancomycin powder to prevent infection in primary total knee arthroplasty: a retrospective review of 976 cases

Authors: Ibrahim Alper Yavuz, Ozdamar Fuad Oken, Ahmet Ozgur Yildirim, Fatih Inci, Erman Ceyhan, Utku Gurhan

Published in: Knee Surgery, Sports Traumatology, Arthroscopy | Issue 9/2020

Abstract

Purpose

Vancomycin powder (VP) has been used to prevent periprosthetic joint infection (PJI). However, studies investigating the efficacy of VP to prevent infection in primary total knee arthroplasty (TKA) are very rare. The purpose of this study was to investigate the efficacy of VP application to prevent PJI in TKA.

Methods

Between 2012 and 2016, 976 consecutive patients who underwent primary TKA were included in the present study. Patients were divided into two groups. There were 474 patients (48.6%) in the VP group and 502 patients in the control group (51.4%). Except for VP, all procedures were the same in both groups. In the VP group, 2 g of VP was poured into the joint just before the fascia was closed. Average follow-up was 53.2 months (24–84 months).

Results

Infection was found in 4 (0.84%) of 474 patients in the VP group and 5 (0.99%) of 502 patients in the control group. There was no statistically significant difference between groups in terms of infection rates (p = 0.535). Staphylococcus aureus was found in 2 patients in the VP group. Two patients had S. aureus and 1 patient had Pseudomonas aeruginosa in the control group. There was no statistically significant difference between groups in terms of demographic parameters (p > 0.05).

Conclusion

Intrawound VP administration doesn’t change the infection rates in primary TKA. The VP administration for preventing PJI is not recommended in primary TKA.

Level of evidence

III.

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Title: No effect of vancomycin powder to prevent infection in primary total knee arthroplasty: a retrospective review of 976 cases
Authors: Ibrahim Alper Yavuz
Ozdamar Fuad Oken
Ahmet Ozgur Yildirim
Fatih Inci
Erman Ceyhan
Utku Gurhan
Publication date: 01-09-2020
Publisher: Springer Berlin Heidelberg
Keywords: Knee-TEP
Wound Debridement
Antibiotic
Knee-TEP
Vancomycin
Joint Infection
Pseudomonas Aeruginosa
Published in: Knee Surgery, Sports Traumatology, Arthroscopy / Issue 9/2020
Print ISSN: 0942-2056
Electronic ISSN: 1433-7347
DOI: https://doi.org/10.1007/s00167-019-05778-8

Keynote webinar | Spotlight on medication adherence

Springer Medicine

No effect of vancomycin powder to prevent infection in primary total knee arthroplasty: a retrospective review of 976 cases

Abstract

Purpose

Methods

Results

Conclusion

Level of evidence

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusion

Level of evidence

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