Skip to main content
Top
Published in: BMC Musculoskeletal Disorders 1/2022

Open Access 01-12-2022 | Knee-TEP | Research

Is there variation in utilization of preoperative tests among patients undergoing total hip and knee replacement in the US, and does it affect outcomes? A population-based analysis

Authors: Mohamed Mosaad Hasan, Raymond Kang, Jungwha Lee, Matthew D. Beal, Abdalrahman G. Ahmed, Yao Tian, Hassan M. K. Ghomrawi

Published in: BMC Musculoskeletal Disorders | Issue 1/2022

Login to get access

Abstract

Study objective

To describe recent practice patterns of preoperative tests and to examine their association with 90-day all-cause readmissions and length of stay.

Design

Retrospective cohort study using the New York Statewide Planning and Research Cooperative System (SPARCS).

Setting

SPARCS from March 1, 2016, to July 1, 2017.

Participants

Adults undergoing Total Hip Replacement (THR) or Total Knee Replacement (TKR) had a preoperative screening outpatient visit within two months before their surgery.

Interventions

Electrocardiogram (EKG), chest X-ray, and seven preoperative laboratory tests (RBCs antibody screen, Prothrombin time (PT) and Thromboplastin time, Metabolic Panel, Complete Blood Count (CBC), Methicillin Resistance Staphylococcus Aureus (MRSA) Nasal DNA probe, Urinalysis, Urine culture) were identified.

Primary and secondary outcome measures

Regression analyses were utilized to determine the association between each preoperative test and two postoperative outcomes (90-day all-cause readmission and length of stay). Regression models adjusted for hospital-level random effects, patient demographics, insurance, hospital TKR, THR surgical volume, and comorbidities. Sensitivity analysis was conducted using the subset of patients with no comorbidities.

Results

Fifty-five thousand ninety-nine patients (60% Female, mean age 66.1+/− 9.8 SD) were included. The most common tests were metabolic panel (74.5%), CBC (66.8%), and RBC antibody screen (58.8%). The least common tests were MRSA Nasal DNA probe (13.0%), EKG (11.7%), urine culture (10.7%), and chest X-ray (7.9%). Carrying out MRSA testing, urine culture, and EKG was associated with a lower likelihood of 90-day all-cause readmissions. The length of hospital stay was not associated with carrying out any preoperative tests. Results were similar in the subset with no comorbidities.

Conclusions

Wide variation exists in preoperative tests before THR and TKR. We identified three preoperative tests that may play a role in reducing readmissions. Further investigation is needed to evaluate these findings using more granular clinical data.
Appendix
Available only for authorised users
Literature
1.
go back to reference Maradit Kremers H, Larson DR, Crowson CS, Kremers WK, Washington RE, Steiner CA, et al. Prevalence of Total Hip and Knee Replacement in the United States. J Bone Joint Surg Am. 2015;97(17):1386–97.CrossRefPubMed Maradit Kremers H, Larson DR, Crowson CS, Kremers WK, Washington RE, Steiner CA, et al. Prevalence of Total Hip and Knee Replacement in the United States. J Bone Joint Surg Am. 2015;97(17):1386–97.CrossRefPubMed
2.
go back to reference King MS. Preoperative evaluation. Am Fam Physician. 2000;62(2):387–96.PubMed King MS. Preoperative evaluation. Am Fam Physician. 2000;62(2):387–96.PubMed
3.
go back to reference Kash BA, Cline KM, Timmons S, Roopani R, Miller TR. International comparison of preoperative testing and assessment protocols and best practices to reduce surgical care costs: a systematic literature review. Adv Health Care Manag. 2015;17:161–94.CrossRefPubMed Kash BA, Cline KM, Timmons S, Roopani R, Miller TR. International comparison of preoperative testing and assessment protocols and best practices to reduce surgical care costs: a systematic literature review. Adv Health Care Manag. 2015;17:161–94.CrossRefPubMed
4.
go back to reference Committee on S, Practice P, Apfelbaum JL, Connis RT, Nickinovich DG, American Society of Anesthesiologists Task Force on Preanesthesia E, et al. Practice advisory for preanesthesia evaluation: an updated report by the American Society of Anesthesiologists Task Force on Preanesthesia Evaluation. Anaesthesia. 2012;116(3):522–38.CrossRef Committee on S, Practice P, Apfelbaum JL, Connis RT, Nickinovich DG, American Society of Anesthesiologists Task Force on Preanesthesia E, et al. Practice advisory for preanesthesia evaluation: an updated report by the American Society of Anesthesiologists Task Force on Preanesthesia Evaluation. Anaesthesia. 2012;116(3):522–38.CrossRef
5.
go back to reference Zhu X, Sun X, Zeng Y, Feng W, Li J, Zeng J, et al. Can nasal Staphylococcus aureus screening and decolonization prior to elective total joint arthroplasty reduce surgical site and prosthesis-related infections? A systematic review and meta-analysis. J Orthop Surg Res. 2020;15(1):60.CrossRefPubMedPubMedCentral Zhu X, Sun X, Zeng Y, Feng W, Li J, Zeng J, et al. Can nasal Staphylococcus aureus screening and decolonization prior to elective total joint arthroplasty reduce surgical site and prosthesis-related infections? A systematic review and meta-analysis. J Orthop Surg Res. 2020;15(1):60.CrossRefPubMedPubMedCentral
6.
go back to reference Czoski-Murray C, Lloyd Jones M, McCabe C, Claxton K, Oluboyede Y, Roberts J, et al. What is the value of routinely testing full blood count, electrolytes and urea, and pulmonary function tests before elective surgery in patients with no apparent clinical indication and in subgroups of patients with common comorbidities: a systematic review of the clinical and cost-effective literature. Health Technol Assess. 2012;16(50):1–159.CrossRef Czoski-Murray C, Lloyd Jones M, McCabe C, Claxton K, Oluboyede Y, Roberts J, et al. What is the value of routinely testing full blood count, electrolytes and urea, and pulmonary function tests before elective surgery in patients with no apparent clinical indication and in subgroups of patients with common comorbidities: a systematic review of the clinical and cost-effective literature. Health Technol Assess. 2012;16(50):1–159.CrossRef
7.
go back to reference Roizen MF. More preoperative assessment by physicians and less by laboratory tests. N Engl J Med. 2000;342(3):204–5.CrossRefPubMed Roizen MF. More preoperative assessment by physicians and less by laboratory tests. N Engl J Med. 2000;342(3):204–5.CrossRefPubMed
8.
go back to reference Klein AA, Arrowsmith JE. Should routine pre-operative testing be abandoned? Anaesthesia. 2010;65(10):974–6.CrossRef Klein AA, Arrowsmith JE. Should routine pre-operative testing be abandoned? Anaesthesia. 2010;65(10):974–6.CrossRef
9.
go back to reference Johansson T, Fritsch G, Flamm M, Hansbauer B, Bachofner N, Mann E, et al. Effectiveness of non-cardiac preoperative testing in non-cardiac elective surgery: a systematic review. Br J Anaesth. 2013;110(6):926–39.CrossRefPubMed Johansson T, Fritsch G, Flamm M, Hansbauer B, Bachofner N, Mann E, et al. Effectiveness of non-cardiac preoperative testing in non-cardiac elective surgery: a systematic review. Br J Anaesth. 2013;110(6):926–39.CrossRefPubMed
10.
go back to reference Kinley H, Czoski-Murray C, George S, McCabe C, Primrose J, Reilly C, et al. Effectiveness of appropriately trained nurses in preoperative assessment: randomised controlled equivalence/non-inferiority trial. BMJ. 2002;325(7376):1323.CrossRefPubMedPubMedCentral Kinley H, Czoski-Murray C, George S, McCabe C, Primrose J, Reilly C, et al. Effectiveness of appropriately trained nurses in preoperative assessment: randomised controlled equivalence/non-inferiority trial. BMJ. 2002;325(7376):1323.CrossRefPubMedPubMedCentral
11.
go back to reference Wijeysundera DN, Austin PC, Beattie WS, Hux JE, Laupacis A. Variation in the practice of preoperative medical consultation for major elective noncardiac surgery: a population-based study. Anesthesiology. 2012;116(1):25–34.CrossRef Wijeysundera DN, Austin PC, Beattie WS, Hux JE, Laupacis A. Variation in the practice of preoperative medical consultation for major elective noncardiac surgery: a population-based study. Anesthesiology. 2012;116(1):25–34.CrossRef
12.
go back to reference Chen CL, Lin GA, Bardach NS, Clay TH, Boscardin WJ, Gelb AW, et al. Preoperative medical testing in Medicare patients undergoing cataract surgery. N Engl J Med. 2015;372(16):1530–8.CrossRefPubMedPubMedCentral Chen CL, Lin GA, Bardach NS, Clay TH, Boscardin WJ, Gelb AW, et al. Preoperative medical testing in Medicare patients undergoing cataract surgery. N Engl J Med. 2015;372(16):1530–8.CrossRefPubMedPubMedCentral
13.
go back to reference Shahian DM, He X, O’Brien SM, Grover FL, Jacobs JP, Edwards FH, et al. Development of a clinical registry-based 30-day readmission measure for coronary artery bypass grafting surgery. Circulation. 2014;130(5):399–409.CrossRef Shahian DM, He X, O’Brien SM, Grover FL, Jacobs JP, Edwards FH, et al. Development of a clinical registry-based 30-day readmission measure for coronary artery bypass grafting surgery. Circulation. 2014;130(5):399–409.CrossRef
14.
go back to reference Filliben JJ, Heckert A. NIST/SEMATECH e-Handbook of Statistical Methods. Gaithersburg: NIST; 2002. Filliben JJ, Heckert A. NIST/SEMATECH e-Handbook of Statistical Methods. Gaithersburg: NIST; 2002.
16.
go back to reference Cangur S, Ankarali H, Pasin O. Comparing Performances of Multiple Comparison Methods in Commonly Used 2 × C Contingency Tables. Inter Sci Com Life Sci. 2016;8(4):337–45. Cangur S, Ankarali H, Pasin O. Comparing Performances of Multiple Comparison Methods in Commonly Used 2 × C Contingency Tables. Inter Sci Com Life Sci. 2016;8(4):337–45.
17.
go back to reference Elixhauser A, Steiner C, Harris DR, Coffey RM. Comorbidity Measures for Use with Administrative Data. Med Care. 1998;36(1):8–27.CrossRefPubMed Elixhauser A, Steiner C, Harris DR, Coffey RM. Comorbidity Measures for Use with Administrative Data. Med Care. 1998;36(1):8–27.CrossRefPubMed
18.
go back to reference SAS Institute. SAS 9.4 Output delivery system: user's guide: SAS institute; 2014. SAS Institute. SAS 9.4 Output delivery system: user's guide: SAS institute; 2014.
19.
go back to reference Brown SR, Brown J. Why do physicians order unnecessary preoperative tests? A qualitative study. Fam Med-Kansas City. 2011;43(5):338. Brown SR, Brown J. Why do physicians order unnecessary preoperative tests? A qualitative study. Fam Med-Kansas City. 2011;43(5):338.
20.
go back to reference Kirkham KR, Wijeysundera DN, Pendrith C, Ng R, Tu JV, Boozary AS, et al. Preoperative Laboratory Investigations: Rates and Variability Prior to Low-risk Surgical Procedures. Anesthesiology. 2016;124(4):804–14.CrossRef Kirkham KR, Wijeysundera DN, Pendrith C, Ng R, Tu JV, Boozary AS, et al. Preoperative Laboratory Investigations: Rates and Variability Prior to Low-risk Surgical Procedures. Anesthesiology. 2016;124(4):804–14.CrossRef
21.
go back to reference Tariq H, Ahmed R, Kulkarni S, Hanif S, Toolsie O, Abbas H, et al. Development, functioning, and effectiveness of a preoperative risk assessment clinic. Health Serv Insights. 2016;9:S40540.CrossRef Tariq H, Ahmed R, Kulkarni S, Hanif S, Toolsie O, Abbas H, et al. Development, functioning, and effectiveness of a preoperative risk assessment clinic. Health Serv Insights. 2016;9:S40540.CrossRef
22.
go back to reference Bozic KJ, Ward L, Vail TP, Maze M. Bundled payments in total joint arthroplasty: targeting opportunities for quality improvement and cost reduction. Clin Orthop Relat Res. 2014;472(1):188–93.CrossRefPubMed Bozic KJ, Ward L, Vail TP, Maze M. Bundled payments in total joint arthroplasty: targeting opportunities for quality improvement and cost reduction. Clin Orthop Relat Res. 2014;472(1):188–93.CrossRefPubMed
23.
go back to reference Barnett ML, Wilcock A, McWilliams JM, Epstein AM, Joynt Maddox KE, Orav EJ, et al. Two-year evaluation of mandatory bundled payments for joint replacement. N Engl J Med. 2019;380(3):252–62.CrossRefPubMedPubMedCentral Barnett ML, Wilcock A, McWilliams JM, Epstein AM, Joynt Maddox KE, Orav EJ, et al. Two-year evaluation of mandatory bundled payments for joint replacement. N Engl J Med. 2019;380(3):252–62.CrossRefPubMedPubMedCentral
24.
go back to reference Stone JL, Hoffman G. Medicare hospital readmissions: issues, policy options and PPACA. Washington, DC: Congressional Research Service; 2010. Stone JL, Hoffman G. Medicare hospital readmissions: issues, policy options and PPACA. Washington, DC: Congressional Research Service; 2010.
25.
go back to reference Fleisher LA, Fleischmann KE, Auerbach AD, Barnason SA, Beckman JA, Bozkurt B, et al. 2014 ACC/AHA guideline on perioperative cardiovascular evaluation and management of patients undergoing noncardiac surgery: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. Circulation. 2014;130(24):e278–333. Fleisher LA, Fleischmann KE, Auerbach AD, Barnason SA, Beckman JA, Bozkurt B, et al. 2014 ACC/AHA guideline on perioperative cardiovascular evaluation and management of patients undergoing noncardiac surgery: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. Circulation. 2014;130(24):e278–333.
26.
go back to reference Fleisher LA, Beckman JA, Brown KA, Calkins H, Chaikof E, Fleischmann KE, et al. ACC/AHA 2007 guidelines on perioperative cardiovascular evaluation and care for noncardiac surgery: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the 2002 Guidelines on Perioperative Cardiovascular Evaluation for Noncardiac Surgery): developed in collaboration with the American Society of Echocardiography, American Society of Nuclear Cardiology, Heart Rhythm Society, Society of Cardiovascular Anesthesiologists, Society for Cardiovascular Angiography and Interventions, Society for Vascular Medicine and Biology, and Society for Vascular Surgery. Circulation. 2007;116(17):e418–99. Fleisher LA, Beckman JA, Brown KA, Calkins H, Chaikof E, Fleischmann KE, et al. ACC/AHA 2007 guidelines on perioperative cardiovascular evaluation and care for noncardiac surgery: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the 2002 Guidelines on Perioperative Cardiovascular Evaluation for Noncardiac Surgery): developed in collaboration with the American Society of Echocardiography, American Society of Nuclear Cardiology, Heart Rhythm Society, Society of Cardiovascular Anesthesiologists, Society for Cardiovascular Angiography and Interventions, Society for Vascular Medicine and Biology, and Society for Vascular Surgery. Circulation. 2007;116(17):e418–99.
27.
go back to reference Gold BS, Young ML, Kinman JL, Kitz DS, Berlin J, Schwartz JS. The utility of preoperative electrocardiograms in the ambulatory surgical patient. Arch Intern Med. 1992;152(2):301–5.CrossRefPubMed Gold BS, Young ML, Kinman JL, Kitz DS, Berlin J, Schwartz JS. The utility of preoperative electrocardiograms in the ambulatory surgical patient. Arch Intern Med. 1992;152(2):301–5.CrossRefPubMed
28.
go back to reference Seymour D, Pringle R, MacLennan W. The role of the routine pre-operative electro-cardiogram in the elderly surgical patient. Age Age. 1983;12(2):97–104.CrossRef Seymour D, Pringle R, MacLennan W. The role of the routine pre-operative electro-cardiogram in the elderly surgical patient. Age Age. 1983;12(2):97–104.CrossRef
29.
go back to reference Kluger M, Tham E, Coleman N, Runciman W, Bullock M. Inadequate pre-operative evaluation and preparation: a review of 197 reports from the Australian Incident Monitoring Study. Anaesthesia. 2000;55(12):1173–8.CrossRef Kluger M, Tham E, Coleman N, Runciman W, Bullock M. Inadequate pre-operative evaluation and preparation: a review of 197 reports from the Australian Incident Monitoring Study. Anaesthesia. 2000;55(12):1173–8.CrossRef
30.
go back to reference Kannaujia AK, Gupta A, Verma S, Srivastava U, Haldar R, Jasuja S. Importance of routine laboratory investigations before elective surgery. Discoveries. 2020;8(3). Kannaujia AK, Gupta A, Verma S, Srivastava U, Haldar R, Jasuja S. Importance of routine laboratory investigations before elective surgery. Discoveries. 2020;8(3).
31.
go back to reference Crowley MP, Fischer B. Routine anaesthesia for joint replacement surgery. Anaes Inten Care Med. 2006;7(3):77–80.CrossRef Crowley MP, Fischer B. Routine anaesthesia for joint replacement surgery. Anaes Inten Care Med. 2006;7(3):77–80.CrossRef
32.
go back to reference Salerno SM, Carlson DW, Soh EK, Lettieri CJ. Impact of perioperative cardiac assessment guidelines on management of orthopedic surgery patients. Am J Med. 2007;120(2):e181–6.CrossRef Salerno SM, Carlson DW, Soh EK, Lettieri CJ. Impact of perioperative cardiac assessment guidelines on management of orthopedic surgery patients. Am J Med. 2007;120(2):e181–6.CrossRef
33.
go back to reference Sadigursky D, Pires HS, Rios SAC, Rodrigues Filho FLB, Queiroz GC, Azi ML. Prophylaxis with nasal decolonization in patients submitted to total knee and hip arthroplasty: systematic review and meta-analysis. Rev Bras Ortop. 2017;52(6):631–7.CrossRefPubMedPubMedCentral Sadigursky D, Pires HS, Rios SAC, Rodrigues Filho FLB, Queiroz GC, Azi ML. Prophylaxis with nasal decolonization in patients submitted to total knee and hip arthroplasty: systematic review and meta-analysis. Rev Bras Ortop. 2017;52(6):631–7.CrossRefPubMedPubMedCentral
34.
go back to reference Zawadzki N, Wang Y, Shao H, Liu E, Song C, Schoonmaker M, et al. Readmission due to infection following total hip and total knee procedures: a retrospective study. Medicine. 2017;96(38). Zawadzki N, Wang Y, Shao H, Liu E, Song C, Schoonmaker M, et al. Readmission due to infection following total hip and total knee procedures: a retrospective study. Medicine. 2017;96(38).
35.
go back to reference Bernatz JT, Tueting JL, Anderson PA. Thirty-day readmission rates in orthopedics: a systematic review and meta-analysis. PLoS ONE. 2015;10(4):e0123593.CrossRefPubMedPubMedCentral Bernatz JT, Tueting JL, Anderson PA. Thirty-day readmission rates in orthopedics: a systematic review and meta-analysis. PLoS ONE. 2015;10(4):e0123593.CrossRefPubMedPubMedCentral
36.
go back to reference Alp E, Cevahir F, Ersoy S, Guney A. Incidence and economic burden of prosthetic joint infections in a university hospital: A report from a middle-income country. J Infect Public Health. 2016;9(4):494–8.CrossRefPubMed Alp E, Cevahir F, Ersoy S, Guney A. Incidence and economic burden of prosthetic joint infections in a university hospital: A report from a middle-income country. J Infect Public Health. 2016;9(4):494–8.CrossRefPubMed
37.
go back to reference Kurtz SM, Lau E, Watson H, Schmier JK, Parvizi J. Economic burden of periprosthetic joint infection in the United States. J Arthroplasty. 2012;27(8):61–65 e61.CrossRefPubMed Kurtz SM, Lau E, Watson H, Schmier JK, Parvizi J. Economic burden of periprosthetic joint infection in the United States. J Arthroplasty. 2012;27(8):61–65 e61.CrossRefPubMed
38.
go back to reference Peel T, Dowsey M, Buising K, Liew D, Choong P. Cost analysis of debridement and retention for management of prosthetic joint infection. Clin Microbiol Infect. 2013;19(2):181–6.CrossRefPubMed Peel T, Dowsey M, Buising K, Liew D, Choong P. Cost analysis of debridement and retention for management of prosthetic joint infection. Clin Microbiol Infect. 2013;19(2):181–6.CrossRefPubMed
39.
go back to reference Tubb CC, Polkowksi GG, Krause B. Diagnosis and prevention of periprosthetic joint infections. JAAOS-J Amer Acad Ortho Surgeons. 2020;28(8):e340–8.CrossRef Tubb CC, Polkowksi GG, Krause B. Diagnosis and prevention of periprosthetic joint infections. JAAOS-J Amer Acad Ortho Surgeons. 2020;28(8):e340–8.CrossRef
40.
go back to reference Mayne AIW, Davies PSE, Simpson JM. Antibiotic treatment of asymptomatic bacteriuria prior to hip and knee arthroplasty; a systematic review of the literature. Surgeon. 2018;16(3):176–82. Mayne AIW, Davies PSE, Simpson JM. Antibiotic treatment of asymptomatic bacteriuria prior to hip and knee arthroplasty; a systematic review of the literature. Surgeon. 2018;16(3):176–82.
41.
go back to reference Gallegos Salazar J, O’Brien W, Strymish JM, Itani K, Branch-Elliman W, Gupta K. Association of Screening and Treatment for Preoperative Asymptomatic Bacteriuria With Postoperative Outcomes Among US Veterans. JAMA Surg. 2019;154(3):241–8.CrossRefPubMed Gallegos Salazar J, O’Brien W, Strymish JM, Itani K, Branch-Elliman W, Gupta K. Association of Screening and Treatment for Preoperative Asymptomatic Bacteriuria With Postoperative Outcomes Among US Veterans. JAMA Surg. 2019;154(3):241–8.CrossRefPubMed
42.
go back to reference Zhang Q, Liu L, Sun W, Gao F, Cheng L, Li Z. Research progress of asymptomatic bacteriuria before arthroplasty: a systematic review. Medicine. 2018;97(7). Zhang Q, Liu L, Sun W, Gao F, Cheng L, Li Z. Research progress of asymptomatic bacteriuria before arthroplasty: a systematic review. Medicine. 2018;97(7).
43.
go back to reference Gomez-Ochoa SA, Espin-Chico BB, Garcia-Rueda NA, Vega-Vera A, Osma-Rueda JL. Risk of Surgical Site Infection in Patients with Asymptomatic Bacteriuria or Abnormal Urinalysis before Joint Arthroplasty: Systematic Review and Meta-Analysis. Surg Infect (Larchmt.). 2019;20(3):159–66.CrossRef Gomez-Ochoa SA, Espin-Chico BB, Garcia-Rueda NA, Vega-Vera A, Osma-Rueda JL. Risk of Surgical Site Infection in Patients with Asymptomatic Bacteriuria or Abnormal Urinalysis before Joint Arthroplasty: Systematic Review and Meta-Analysis. Surg Infect (Larchmt.). 2019;20(3):159–66.CrossRef
44.
go back to reference Osborne TF, Suarez P, Edwards D, Hernandez-Boussard T, Curtin C. Patient electronic health records score for preoperative risk assessment before total knee arthroplasty. JBJS Open Access. 2020;5(2). Osborne TF, Suarez P, Edwards D, Hernandez-Boussard T, Curtin C. Patient electronic health records score for preoperative risk assessment before total knee arthroplasty. JBJS Open Access. 2020;5(2).
Metadata
Title
Is there variation in utilization of preoperative tests among patients undergoing total hip and knee replacement in the US, and does it affect outcomes? A population-based analysis
Authors
Mohamed Mosaad Hasan
Raymond Kang
Jungwha Lee
Matthew D. Beal
Abdalrahman G. Ahmed
Yao Tian
Hassan M. K. Ghomrawi
Publication date
01-12-2022
Publisher
BioMed Central
Published in
BMC Musculoskeletal Disorders / Issue 1/2022
Electronic ISSN: 1471-2474
DOI
https://doi.org/10.1186/s12891-022-05945-y

Other articles of this Issue 1/2022

BMC Musculoskeletal Disorders 1/2022 Go to the issue