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01-12-2023 | Keratomileusis | Original Article

Seven-year corneal densitometry changes after small incision lenticule extraction and femtosecond laser-assisted in situ keratomileusis

Authors: Tian Han, Luoli Zhang, Yangyi Huang, Yang Shen, Xingtao Zhou, Ye Xu

Published in: Lasers in Medical Science | Issue 1/2023

Abstract

This study aims to investigate the 7-year changes in corneal densitometry (CD) after small incision lenticule extraction (SMILE) and femtosecond laser-assisted in situ keratomileusis (FS-LASIK). Forty-two eyes undergoing SMILE and thirty-one undergoing FS-LASIK were included in this retrospective study. CD was measured preoperatively and at 3 and 7 years postoperatively. Three concentric radial zones (0–2, 2–6, and 6–10 mm) of three different corneal depths (anterior 120 μm, posterior 60 μm, and central layer) were analyzed. In all three zones of the three corneal layers, no significant difference in CD was found between the two groups preoperatively and at 3 and 7 years postoperatively (all P > 0.05). All CD values in the three zones of the anterior and central layers significantly declined at 3 years postoperatively (all P < 0.001), and then increased at 7 years postoperatively compared to corresponding 3-year values (all P < 0.01). In the posterior layer, CD values in the 0–2-mm and 2–6-mm zones decreased at 3 years postoperatively (all P < 0.01) and continued to decrease at 7 years postoperatively (all P < 0.01). Similar CD trends were observed after SMILE and FS-LASIK. Posterior layer CD showed a decrease throughout the study period. In the anterior and central layers, CD values decreased and then increased at 7 years postoperatively. The transparency changes might have been due to age-related three-dimensional growth of collagen fibers and wound-healing reactions.

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Title: Seven-year corneal densitometry changes after small incision lenticule extraction and femtosecond laser-assisted in situ keratomileusis
Authors: Tian Han
Luoli Zhang
Yangyi Huang
Yang Shen
Xingtao Zhou
Ye Xu
Publication date: 01-12-2023
Publisher: Springer London
Keywords: Keratomileusis
Incision
Laser
Published in: Lasers in Medical Science / Issue 1/2023
Print ISSN: 0268-8921
Electronic ISSN: 1435-604X
DOI: https://doi.org/10.1007/s10103-023-03850-x

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Seven-year corneal densitometry changes after small incision lenticule extraction and femtosecond laser-assisted in situ keratomileusis

Abstract

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Abstract

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