Skip to main content
Top
Published in: Pediatric Radiology 4/2024

29-08-2023 | Juvenile Rheumatoid Arthritis | ESPR

The role of radiography in diagnosing, monitoring and prognosing juvenile idiopathic arthritis

Authors: Damjana Ključevšek, Vesna Potočnik Tumpaj, Ana Gazikalović

Published in: Pediatric Radiology | Issue 4/2024

Login to get access

Abstract

The current role of conventional radiography in the diagnosis, monitoring and prognosis of juvenile idiopathic arthritis (JIA) is reviewed, as its role has changed with the increasing use of ultrasound and magnetic resonance imaging, as well as with the introduction of biological drugs. Conventional radiography does not play an important role in the diagnosis of JIA, as this is based on history, clinical examination and laboratory findings. The main role of conventional radiography is in the detection and monitoring of growth disorders and chronic structural and morphological changes of the affected joints and bones, in addition to helping with the differential diagnosis of conditions that mimic JIA. Radiographic changes of the joints depend on the age of the child, the type and duration of arthritis and the specific joints affected. There are no standard protocols for arthritis monitoring and most indications for imaging are based on individual case-by-case decisions. The development of degenerative joint changes is considered a poor predictive factor, but there are no clear studies that more precisely define the predictive value of radiographic changes. Conventional radiography remains an important imaging modality in narrowing the differential diagnosis and in evaluating growth disorders and the developing destructive joint changes.

Graphical abstract

Appendix
Available only for authorised users
Literature
1.
go back to reference Sudoł-Szopińska I, Matuszewska G, Gietka P et al (2016) Imaging of juvenile idiopathic arthritis. Part I: Clinical classifications and radiographs. J Ultrason 16:225–236CrossRefPubMedPubMedCentral Sudoł-Szopińska I, Matuszewska G, Gietka P et al (2016) Imaging of juvenile idiopathic arthritis. Part I: Clinical classifications and radiographs. J Ultrason 16:225–236CrossRefPubMedPubMedCentral
3.
go back to reference Southwood T (2008) Juvenile idiopathic arthritis: clinically relevant imaging in diagnosis and monitoring. Pediatr Radiol 38:S395–S402CrossRefPubMed Southwood T (2008) Juvenile idiopathic arthritis: clinically relevant imaging in diagnosis and monitoring. Pediatr Radiol 38:S395–S402CrossRefPubMed
4.
go back to reference Hemke R, Herregods N, Jaremko JL et al (2020) Imaging assessment of children presenting with suspected or known juvenile idiopathic arthritis: ESSR-ESPR points to consider. Eur Radiol 30:5237–5249CrossRefPubMedPubMedCentral Hemke R, Herregods N, Jaremko JL et al (2020) Imaging assessment of children presenting with suspected or known juvenile idiopathic arthritis: ESSR-ESPR points to consider. Eur Radiol 30:5237–5249CrossRefPubMedPubMedCentral
5.
go back to reference Breton S, Jousse-Joulin S, Finel E et al (2012) Imaging approaches for evaluating peripheral joint abnormalities in juvenile idiopathic arthritis. Semin Arthritis Rheum 41:698–711CrossRefPubMed Breton S, Jousse-Joulin S, Finel E et al (2012) Imaging approaches for evaluating peripheral joint abnormalities in juvenile idiopathic arthritis. Semin Arthritis Rheum 41:698–711CrossRefPubMed
6.
go back to reference Doria AS, Babyn PS, Feldman B (2006) A critical appraisal of radiographic scoring systems for assessment of juvenile idiopathic arthritis. Pediatr Radiol 36:759–772CrossRefPubMed Doria AS, Babyn PS, Feldman B (2006) A critical appraisal of radiographic scoring systems for assessment of juvenile idiopathic arthritis. Pediatr Radiol 36:759–772CrossRefPubMed
7.
go back to reference Ravelli A (2008) The time has come to include assessment of radiographic progression in juvenile idiopathic arthritis clinical trials. J Rheumatol 35:553–557PubMed Ravelli A (2008) The time has come to include assessment of radiographic progression in juvenile idiopathic arthritis clinical trials. J Rheumatol 35:553–557PubMed
8.
go back to reference Wihlborg C, Babyn P, Ranson M, Laxer R (2001) Radiologic mimics of juvenile rheumatoid arthritis. Pediatr Radiol 31:315–326CrossRefPubMed Wihlborg C, Babyn P, Ranson M, Laxer R (2001) Radiologic mimics of juvenile rheumatoid arthritis. Pediatr Radiol 31:315–326CrossRefPubMed
9.
go back to reference Sheybani EF, Khanna G, White AJ et al (2013) Imaging of juvenile idiopathic arthritis: a multimodality approach. RadioGraphics 33:1253–1273CrossRefPubMed Sheybani EF, Khanna G, White AJ et al (2013) Imaging of juvenile idiopathic arthritis: a multimodality approach. RadioGraphics 33:1253–1273CrossRefPubMed
10.
go back to reference Matuszewska G, Zaniewicz-Kaniewska K, Włodkowska-Korytkowska M et al (2014) Radiological imaging in pediatric rheumatic diseases. Pol. J Radiol 79:51–58 Matuszewska G, Zaniewicz-Kaniewska K, Włodkowska-Korytkowska M et al (2014) Radiological imaging in pediatric rheumatic diseases. Pol. J Radiol 79:51–58
12.
go back to reference Malattia C, Rinaldi M, Martini A (2018) The role of imaging in juvenile idiopathic arthritis. Expert Rev Clin Immunol 14:681–694CrossRefPubMed Malattia C, Rinaldi M, Martini A (2018) The role of imaging in juvenile idiopathic arthritis. Expert Rev Clin Immunol 14:681–694CrossRefPubMed
13.
go back to reference Kjellberg H (2011) Pavlou I (2011) Changes in the cervical spine of children with juvenile idiopathic arthritis evaluated with lateral cephalometric radiographs: a case control study. Angle Orthod. 81:447–452CrossRefPubMedPubMedCentral Kjellberg H (2011) Pavlou I (2011) Changes in the cervical spine of children with juvenile idiopathic arthritis evaluated with lateral cephalometric radiographs: a case control study. Angle Orthod. 81:447–452CrossRefPubMedPubMedCentral
14.
go back to reference Kotecki M, Gietka P, Posadzy M et al (2021) Radiographs and MRI of the cervical spine in juvenile idiopathic arthritis: a cross-sectional retrospective study. J Clin Med 10:5798CrossRefPubMedPubMedCentral Kotecki M, Gietka P, Posadzy M et al (2021) Radiographs and MRI of the cervical spine in juvenile idiopathic arthritis: a cross-sectional retrospective study. J Clin Med 10:5798CrossRefPubMedPubMedCentral
15.
go back to reference Maldonado-Cocco JA, García-Morteo O, Spindler AJ (1980) Carpal ankylosis in juvenile rheumatoid arthritis. Arthritis and Rheumatism 23:1251–1255CrossRefPubMed Maldonado-Cocco JA, García-Morteo O, Spindler AJ (1980) Carpal ankylosis in juvenile rheumatoid arthritis. Arthritis and Rheumatism 23:1251–1255CrossRefPubMed
16.
go back to reference Posadzy M, Sowińska A, Vanhoenacker F et al (2022) Foot and ankle conventional radiography in juvenile idiopathic arthritis: does it still matter? J Belg Soc Radiol 106:87CrossRefPubMedPubMedCentral Posadzy M, Sowińska A, Vanhoenacker F et al (2022) Foot and ankle conventional radiography in juvenile idiopathic arthritis: does it still matter? J Belg Soc Radiol 106:87CrossRefPubMedPubMedCentral
18.
go back to reference d’Angelo DM, Di Donato G, Breda L et al (2021) Growth and puberty in children with juvenile idiopathic arthritis. Pediatr Rheumatol Online J. 12(19):28CrossRef d’Angelo DM, Di Donato G, Breda L et al (2021) Growth and puberty in children with juvenile idiopathic arthritis. Pediatr Rheumatol Online J. 12(19):28CrossRef
19.
go back to reference Gilsanz V, Ratib O (2012) Hand bone age a digital atlas of skeletal maturity. Berlin, Heidelberg: Springer Berlin Heidelberg. Pages 14 and 15. Gilsanz V, Ratib O (2012) Hand bone age a digital atlas of skeletal maturity. Berlin, Heidelberg: Springer Berlin Heidelberg. Pages 14 and 15.
21.
go back to reference Ravelli A, Ioseliani M, Norambuena X et al (2007) Adapted versions of the Sharp/van der Heijde score are reliable and valid for assessment of radiographic progression in juvenile idiopathic arthritis. Arthritis Rheum 56:3087–3095CrossRefPubMed Ravelli A, Ioseliani M, Norambuena X et al (2007) Adapted versions of the Sharp/van der Heijde score are reliable and valid for assessment of radiographic progression in juvenile idiopathic arthritis. Arthritis Rheum 56:3087–3095CrossRefPubMed
22.
go back to reference Shelmerdine SC, Di Paolo PL, Rieter JFMM et al (2018) A novel radiographic scoring system for growth abnormalities and structural change in children with juvenile idiopathic arthritis of the hip. Pediatr Radiol 48:1086–1095CrossRefPubMedPubMedCentral Shelmerdine SC, Di Paolo PL, Rieter JFMM et al (2018) A novel radiographic scoring system for growth abnormalities and structural change in children with juvenile idiopathic arthritis of the hip. Pediatr Radiol 48:1086–1095CrossRefPubMedPubMedCentral
23.
go back to reference Pettersson H, Rydholm U (1984) Radiologv classification of knee joint destruction in juvenile chronic arthritis. Pediatr Radiol 14:419–431CrossRefPubMed Pettersson H, Rydholm U (1984) Radiologv classification of knee joint destruction in juvenile chronic arthritis. Pediatr Radiol 14:419–431CrossRefPubMed
25.
go back to reference Marteau P, Adamsbaum C, Rossi-Semerano L et al (2018) Conventional radiography in juvenile idiopathic arthritis: joint recommendations from the French societies for rheumatology, radiology and paediatric rheumatology. Eur Radiol 28:3963–3976CrossRefPubMedPubMedCentral Marteau P, Adamsbaum C, Rossi-Semerano L et al (2018) Conventional radiography in juvenile idiopathic arthritis: joint recommendations from the French societies for rheumatology, radiology and paediatric rheumatology. Eur Radiol 28:3963–3976CrossRefPubMedPubMedCentral
26.
go back to reference Giancane G, Pederzoli S, Norambuena X et al (2014) Frequency of radiographic damage and progression in individual joints in children with juvenile idiopathic arthritis. Arthritis Care Res 66:27–33CrossRef Giancane G, Pederzoli S, Norambuena X et al (2014) Frequency of radiographic damage and progression in individual joints in children with juvenile idiopathic arthritis. Arthritis Care Res 66:27–33CrossRef
27.
go back to reference Bertamino M, Rossi F, Pistorio A et al (2010) Development and initial validation of a radiographic scoring system for the hip in juvenile idiopathic arthritis. J Rheumatol 37:432–439CrossRefPubMed Bertamino M, Rossi F, Pistorio A et al (2010) Development and initial validation of a radiographic scoring system for the hip in juvenile idiopathic arthritis. J Rheumatol 37:432–439CrossRefPubMed
28.
go back to reference Magni-Manzoni S, Rossi F, Pistorio A et al (2003) Prognostic factors for radiographic progression, radiographic damage, and disability in juvenile idiopathic arthritis. Arthritis Rheumatism 48:3509–3517CrossRefPubMed Magni-Manzoni S, Rossi F, Pistorio A et al (2003) Prognostic factors for radiographic progression, radiographic damage, and disability in juvenile idiopathic arthritis. Arthritis Rheumatism 48:3509–3517CrossRefPubMed
Metadata
Title
The role of radiography in diagnosing, monitoring and prognosing juvenile idiopathic arthritis
Authors
Damjana Ključevšek
Vesna Potočnik Tumpaj
Ana Gazikalović
Publication date
29-08-2023
Publisher
Springer Berlin Heidelberg
Published in
Pediatric Radiology / Issue 4/2024
Print ISSN: 0301-0449
Electronic ISSN: 1432-1998
DOI
https://doi.org/10.1007/s00247-023-05742-2

Other articles of this Issue 4/2024

Pediatric Radiology 4/2024 Go to the issue

ESPR Belgrade 2023 - Postgraduate Course and Taskforce Lectures

Lung infections in immunocompromised children

ESPR Belgrade 2023 - Postgraduate Course and Taskforce Lectures

Unusual pediatric lung infections: imaging findings